Results 111 to 120 of about 3,919,853 (296)

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Feral pigs as a reservoir for zoonotic and transboundary diseases in the Western Pacific Region

open access: yesWestern Pacific Surveillance and Response
Feral pigs are known as triple-threat pests due to their impact on health, agriculture and the ecosystem. Recent emerging infectious disease outbreaks have emphasized their role as reservoirs and amplifiers of disease and highlight the need for increased
Andrew M Adamu   +5 more
doaj   +1 more source

Animal agency, animal awareness and animal welfare

open access: yesAnimal Welfare, 2019
AbstractIn nature, animals need to actively engage with the environment in order to prosper in survival and reproduction. Hence, agency is a central adaptive characteristic of animal life. In this paper, I propose that from the adaptive/functional point of view, four levels of agency can be distinguished, namely passive/reactive agency (animal being ...
openaire   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Balenes i altres animals marins [PDF]

open access: yes, 2011
Ensino Fundamental::Séries Iniciais::Ciências NaturaisL'objecte de les obres d'educació amb els animals marins i les seves diverses classificacionsCal que l'estudiant té el coneixement sobre els animals ...
Viñals Serra, Lídia
core   +2 more sources

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

EXPERIMENTAL STUDY OF THE DIURETIC ACTIVITY AMONG 7-SUBSTITUTED-3-METHYL-8- MORPHLINOXANTHINES [PDF]

open access: yesAnnals of Mechnikov's Institute, 2013
The experimental study of influence on functional activityof kidney of 14 compounds among 7-substituted-3-methyl-8-morpholinoxanthines synthesized for the firsttime and also some mechanisms of this action were stud-ied.
Bakumenko M.G.
doaj  

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Home - About - Disclaimer - Privacy