Results 121 to 130 of about 6,118,059 (309)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Animal poisonings in Belgium: a review of the past decade [PDF]
, 2010 This review focuses on poisonings in companion animals, including horses, farm animals and wildlife, investigated and recorded during the past ten years at the Laboratory of Toxicology of the Faculty of Veterinary Medicine (Ghent University) and the ...
Croubels, Siska +3 more
core +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Frontiers in Veterinary ScienceIntroductionDespite its endemic status and socioeconomic impacts, the spatial-temporal variation in rabies risk and its underlying determinants in Kazakhstan animal populations remain poorly understood.
Alberto Gomez-Buendia +9 more
doaj +1 more source
Reduction of slaughterhouse stress in beef cattle by facilitating animal tameness [PDF]
, 2011 The relationship between animals and humans is important for animal husbandry and welfare. Loosehousing and grazing systems with low management input often result in frail relationships between humans and animals.
Hillmann, Edna +4 more
core
Physical Review EHere we introduce simple structures for the analysis of complex hypergraphs, hypergraph animals. These structures are designed to describe the local node neighbourhoods of nodes in hypergraphs. We establish their relationships to lattice animals and network motifs, and we develop their combinatorial properties for sparse and uncorrelated hypergraphs ...
openaire +3 more sources
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
THE FINAL (MISSIONS) FRONTIER: EXTRATERRESTRIALS, EVANGELISM, AND THE WIDE CIRCLE OF HUMAN EMPATHY
Zygon, 2019 The possible existence of extraterrestrials has provoked more than five centuries of theological speculation on how these beings, if they exist, relate to God.
doaj +2 more sources
Two Views of Animals in Environmental Ethics [PDF]
, 2016 This chapter concerns the role accorded to animals in the theories of the English-speaking philosophers who created the field of environmental ethics in the latter half of the twentieth century.
Gary, Comstock
core