Results 131 to 140 of about 6,118,059 (309)
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Animals as reflexive thinkers: The aponoian paradigm [PDF]
The ability to engage in reflexive thought—in thought about thought or about other mental states more generally—is regarded as a complex intellectual achievement that is beyond the capacities of most nonhuman animals. To the extent that reflexive thought
Monsó, Susana, Rowlands, Mark
core
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
One of the most significant contributions to the field in recent times, David Clough's work On Animals: Volume 1, Systematic Theology, should ensure that theologies of creation, redemption, and eschatological fulfillment give proper attention to animals.
doaj +2 more sources
Expanding Global Justice: The International Protection of Animals [PDF]
This article examines and rejects the view that nonhuman animals cannot be recipients of justice, and argues that the main reasons in favor of universal human rights and global justice also apply in the case of the international protection of the ...
Horta, Oscar
core
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
ON THINKING THEOLOGICALLY ABOUT ANIMALS: A RESPONSE
In response to evaluations of On Animals: Volume 1, Systematic Theology by Margaret Adams, Christopher Carter, David Fergusson, and Stephen Webb, this article argues that the theological reappraisals of key doctrines argued for in the book are important
doaj +2 more sources
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Animal agency, animal awareness and animal welfare
AbstractIn nature, animals need to actively engage with the environment in order to prosper in survival and reproduction. Hence, agency is a central adaptive characteristic of animal life. In this paper, I propose that from the adaptive/functional point of view, four levels of agency can be distinguished, namely passive/reactive agency (animal being ...
openaire +1 more source
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source

