Results 171 to 180 of about 9,120,435 (385)

Anti-EMT and anti-fibrosis effects of protocatechuic aldehyde in renal proximal tubular cells and the unilateral ureteral obstruction animal model [PDF]

, 2022
Yu-Teng Chang, Mu‐Chi Chung, Chi-Hao Chang, Kuan-Hsun Chiu, Jeng‐Jer Shieh, Ming‐Ju Wu   +5 more
openalex   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Transcranial magnetic stimulation in animal models of neurodegeneration

, 2021
Shahid Bashir, Mohammad Uzair, Turki Abualait, Arshad Muhammad, Woo‐Kyoung Yoo, Ali Mir, ReemFahd Bunyan   +6 more
openalex   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Disentangling the relative roles of resource acquisition and allocation on animal feed efficiency: insights from a dairy cow model [PDF]

, 2016
Laurence Puillet, Denis Réale, N.C. Friggens   +2 more
openalex   +1 more source

Structure-based discovery of potent WD repeat domain 5 inhibitors that demonstrate efficacy and safety in preclinical animal models

, 2022
Kevin B. Teuscher, Somenath Chowdhury, Kenneth M. Meyers, Jianhua Tian, Jiqing Sai, Mayme Van Meveren, Taylor M. South, John Sensintaffar, Tyson A. Rietz, Soumita Goswami, Jing Wang, Brian C. Grieb, Shelly L. Lorey, Gregory C. Howard, Qi Liu, William Moore, Gordon M. Stott, William P. Tansey, Taekyu Lee, Stephen W. Fesik   +19 more
openalex   +2 more sources

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Mitoapocynin Treatment Protects Against Neuroinflammation and Dopaminergic Neurodegeneration in a Preclinical Animal Model of Parkinson’s Disease

, 2016
Anamitra Ghosh, Monica R. Langley, Dilshan S. Harischandra, Matthew L. Neal, Huajun Jin, Vellareddy Anantharam, Joy Joseph, Timothy M. Brenza, Balaji Narasimhan, Arthi Kanthasamy, Balaraman Kalyanaraman, Anumantha G. Kanthasamy   +11 more
openalex   +1 more source

Cardiac dysfunction in an animal model of neonatal asphyxia is associated with increased degradation of MLC1 by MMP-2 [PDF]

, 2009
Adrian Doroszko, Dorota Polewicz, Jolanta Sawicka, J. Steven Richardson, Po‐Yin Cheung, Grzegorz Sawicki   +5 more
openalex   +1 more source

Guide for the Care and Use of Laboratory Animals

, 1996
Andrew N. Rowan
semanticscholar   +1 more source