Results 241 to 250 of about 8,895,509 (405)

Invertebrate animals of the Lake District [PDF]

, 1938
Macan, T.T.
core  

Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management

Molecular Oncology, EarlyView.
DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez, Asieh Naderi, Kim‐Tuyen Huynh‐Dam, Vitali Sikirzhytski, Ioulia Chatzistamou, Hippokratis Kiaris   +5 more
wiley   +1 more source

A call to action to address critical flaws and bias in laboratory animal experiments and preclinical research. [PDF]

Sci Rep
Townsend HGG, Osterrieder K, Jelinski MD, Morck DW, Waldner CL, Cox WR, Gerdts V, Potter AA, Babiuk LA, Cross JC.   +9 more
europepmc   +1 more source

Raphin‐1 mediates the survival and sensitivity to radiation of pediatric‐type diffuse high‐grade glioma via phosphorylated eukaryotic initiation factor 2α‐dependent and ‐independent processes

Molecular Oncology, EarlyView.
Raphin‐1 reduces the survival of PED‐DHGG cells and enhances their radiation sensitivity through both PeIF2α‐dependent and PeIF2α‐independent mechanisms. Raphin‐1 sustains elevated levels of PeIF2α, contributing to its PeIF2α‐dependent effects. Additionally, raphin‐1 interacts with CReP to mediate a separate radiosensitizing pathway that operates ...
Karin Eytan, Moshe Leitner, Amos Toren, Shoshana Paglin, Michal Yalon   +4 more
wiley   +1 more source

Effectiveness of electrical stunning and bleeding in finishing pigs: a case study from procedures to practice at two modern Colombian abattoirs. [PDF]

Trop Anim Health Prod
Pastrana-Camacho AP, Estévez-Moreno LX, Huanca-Marca NF, la Lama GCM.   +3 more
europepmc   +1 more source

On the origin and destiny of cholesterol in the animal organism. Part XII.—On the excretion of sterols in man

, 1921
John A. Gardner, F. W. Fox
openalex   +1 more source

Bryozoa as Food for Other Animals [PDF]

, 1921
Raymond C. Osburn
openalex   +1 more source

Intracellular innate immune surveillance devices in plants and animals

Science, 2016
Jonathan D. G. Jones, R. Vance, J. Dangl
semanticscholar   +1 more source

Targeting carbonic anhydrase IX/XII prevents the anti‐ferroptotic effect of stromal lactic acid in prostate carcinoma

Molecular Oncology, EarlyView.
In prostate carcinoma, lactic acid, secreted by highly glycolytic cancer‐associated fibroblasts, is imported into tumor cells through the MCT1 transporter and prevents RSL3 and erastin‐induced ferroptosis (A). Targeting of carbonic anhydrase IX/XII, the main extracellular pH regulators, in tumor and stromal cells reduces microenvironmental acidosis and
Elisa Pardella, Giuseppina Comito, Luigi Ippolito, Erica Pranzini, Marta Iozzo, Giulia Gangarossa, Francesca Virgilio, Silvia Bua, Alessio Nocentini, Giada Sandrini, Nicla Lorito, Marina Bacci, Gabriella Nesi, Pietro Spatafora, Sergio Serni, Claudiu T. Supuran, Andrea Morandi, Paola Chiarugi, Elisa Giannoni   +18 more
wiley   +1 more source

The kinase GSK-3 alters the RNA-binding protein landscape of lipid metabolism transcripts leading to altered expression in the C. elegans nervous system. [PDF]

Nucleic Acids Res
Mahapatra A, Mohankumar M, Hundley HA.
europepmc   +1 more source