Results 281 to 290 of about 9,215,153 (385)

A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy

Molecular Oncology, EarlyView.
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti, Giovanni Germano, Pietro Paolo Vitiello, Alberto Bardelli   +3 more
wiley   +1 more source

Disconnexion syndromes in animals and man. I.

Brain : a journal of neurology, 1965
N. Geschwind
semanticscholar   +1 more source

The conserved outer mitochondrial membrane protein Mtch regulates mitophagy during Drosophila intestinal development. [PDF]

PLoS Biol
Restrepo LJ, Graslie JK, Fortier TM, Baehrecke EH.   +3 more
europepmc   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Large-particle aerosol exposure to the Bangladesh or Malaysia strain of Nipah virus results in markedly divergent disease presentation in African Green Monkeys. [PDF]

PLoS Pathog
Cong Y, Bearss J, Mani V, Lackemeyer M, Pahar B, Huzella LM, Kollins E, Mazur S, Dixit S, Lembirik S, Drawbaugh D, Sayre PJ, Laux J, Solomon J, Hammoud DA, Lee JH, Calcagno C, Byrum R, St Claire M, Wada J, Munster V, Holbrook MR.   +21 more
europepmc   +1 more source

Invertebrate animals of the Lake District [PDF]

, 1938
Macan, T.T.
core  

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Food Animals and Antimicrobials: Impacts on Human Health

Clinical Microbiology Reviews, 2011
B. Marshall, S. Levy
semanticscholar   +1 more source

Transplanted gene-modified placental cells boost FVIII activity in pediatric sheep without eliciting immunity, toxicity, or adverse events. [PDF]

Front Immunol
Trevisan B, Rodriguez M, Ramamurthy R, George S, Babatunde OO, Dizon J, Shields J, Lankford S, Schwahn D, Gautreaux M, Farland A, Owen J, Atala A, Doering CB, Spencer HT, Porada CD, Almeida-Porada G.   +16 more
europepmc   +1 more source

Raiva animal na cidade do Rio de Janeiro: emergência da doença em morcegos e novos desafios para o controle

, 2000
Priscilla Gomes de Souza, Barbara Maria Padão Montes do AMARAL, Clayton Bernardinelli Gitti   +2 more
openalex   +2 more sources