Results 131 to 140 of about 373,177 (393)
Marine Drugs, 2017 This study examined the urinary excretion of tetrodotoxin (TTX) modeled in a porcine renal proximal tubule epithelial cell line, LLC-PK1. Time course profiles of TTX excretion and reabsorption across the cell monolayers at 37 °C showed that the amount of
Takuya Matsumoto +6 more
doaj +1 more source
Journal of Immunology, 1994 Tenidap is a novel anti-inflammatory and antiarthritic agent that in clinical studies of rheumatoid arthritis patients, displays symptomatic efficacy superior to nonsteroidal anti-inflammatory drugs (NSAIDs) and equivalent to combinations of NSAIDs and ...
P. McNiff +3 more
semanticscholar +1 more source
TLR Agonist Nano Immune Therapy Clears Peritoneal and Systemic Ovarian Cancer
Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.Intraperitoneal administration of immunogenic Toll‐like receptor agonist‐modified mesoporous silica nanoparticles leads to rapid internalization by ascites myeloid cells with trafficking to fat‐associated lymphoid clusters. Activation of myeloid cells counters suppressive immune mechanisms associated with peritoneal metastasis, leading to regional and ...
Ben Marwedel +15 more
wiley +1 more source
Pharmaceutics, 2011 Antiretrovirals are prone to drug-drug and drug-food interactions that can result in subtherapeutic or supratherapeutic concentrations. Interactions between antiretrovirals and medications for other diseases are common due to shared metabolism through ...
R. Chris Rathbun, Michelle D. Liedtke
doaj +1 more source
Recent Applications of Mesoporous Silica Nanoparticles in Gene Therapy
Advanced Healthcare Materials, EarlyView.The review summarizes the synthesis of mesoporous silica nanoparticles (MSNs) with modifiable surface properties, functionalization strategies, mechanism of therapeutic payload release, and current applications in gene therapy, focusing on their capabilities in the targeted delivery of therapeutic nucleic acids, CRISPR‐Cas systems, and other genetic ...
Tamanna Binte Huq +4 more
wiley +1 more source
Molecular and Functional Analyses of Transport Proteins for Organic Anions
, 2006 The blood-cerebrospinal fluid (CSF)-barrier (CSFB) is formed by the Choroid Plexūs (CP). Together with the blood brain barrier it represents an important barrier between brain and circulating blood. Since it can only be passed by small, lipid-soluble and uncharged molecules it is of particular interest to study active transport processes for charged ...
openaire +2 more sources
Advanced Healthcare Materials, EarlyView.Negative‐ and positive‐staining TEM is essential for rapid nanometer‐resolution characterization of organic specimens ranging from nanoparticles to cells. Uranyl salts are widely used negative‐/positive‐stains but are radioactive and highly toxic to users and the environment.
Vera M. Kissling +4 more
wiley +1 more source
The Scaled-Charge Additive Force Field for Amino Acid Based Ionic Liquids
, 2014 . Ionic liquids (ILs) constitute an emerging field of research. New ILs are continuously introduced involving more and more organic and inorganic ions.
Chaban, Vitaly V., Fileti, Eudes Eterno
core +1 more source
Rat Erythrocytes Express the Anionic Amino Acid Transport Protein EAAC1
Blood Cells, Molecules, and Diseases, 2002 EAAC1 is a widely expressed protein which transports anionic amino acids in a Na(+)-dependent fashion. Rat erythrocytes have generally been thought to be impermeant to anionic amino acids. Utilizing immunoelectron microscopy, we have demonstrated the presence of EAAC1-immunoreactive protein within rat erythrocytes.
Department of Pediatrics, University of Florida College of Medicine, Gainesville, Florida ( host institution ) +3 more
openaire +4 more sources