Results 1 to 10 of about 904,466 (167)

Investigating the Properties of ABS-Based Plastic Composites Manufactured by Composite Plastic Manufacturing

open access: yesJournal of Manufacturing and Materials Processing, 2022
Additive manufacturing (AM) technologies have revolutionized the manufacturing sector due to their benefits, such as design flexibility, ease of operation, and wide material selection.
Raghunath Bhaskar   +2 more
doaj   +1 more source

Mechanistic in vitro studies indicate that the clinical drug–drug interactions between protease inhibitors and rosuvastatin are driven by inhibition of intestinal BCRP and hepatic OATP1B1 with minimal contribution from OATP1B3, NTCP and OAT3

open access: yesPharmacology Research & Perspectives, 2023
Previous use of a mechanistic static model to accurately quantify the increased rosuvastatin exposure due to drug–drug interaction (DDI) with coadministered atazanavir underpredicted the magnitude of area under the plasma concentration–time curve ratio ...
Robert Elsby   +5 more
doaj   +1 more source

Quantitative phase microscopy for non-invasive live cell population monitoring

open access: yesScientific Reports, 2021
We present here a label-free development based on preexisting Quantitative Phase Imaging (QPI) that allows non-invasive live monitoring of both individual cells and cell populations.
Sherazade Aknoun   +7 more
doaj   +1 more source

Bidirectional regulation of glial potassium buffering – glioprotection versus neuroprotection

open access: yeseLife, 2021
Glia modulate neuronal excitability and seizure sensitivity by maintaining potassium and water homeostasis. A salt inducible kinase 3 (SIK3)-regulated gene expression program controls the glial capacity to buffer K+ and water in Drosophila, however ...
Hailun Li   +2 more
doaj   +1 more source

Metabolome of Cerebral Thrombi Reveals an Association between High Glycemia at Stroke Onset and Good Clinical Outcome

open access: yesMetabolites, 2020
Despite the fact that glucose is the main fuel of the brain, hyperglycemia at hospital admission is generally associated with a poor functional outcome in stroke patients.
Laurent Suissa   +8 more
doaj   +1 more source

Genome and Evolutionary Analysis of Nosema ceranae: A Microsporidian Parasite of Honey Bees

open access: yesFrontiers in Microbiology, 2021
Microsporidia comprise a phylum of single cell, intracellular parasites and represent the earliest diverging branch in the fungal kingdom. The microsporidian parasite Nosema ceranae primarily infects honey bee gut epithelial cells, leading to impaired ...
Qiang Huang   +10 more
doaj   +1 more source

Extracellular Production of Glutathione by Recombinant Escherichia coli K-12

open access: yesMicrobiology Research, 2023
The goal of this study was to produce a sufficient amount of glutathione in the fermentation medium without the addition of cysteine. This would simplify and reduce the cost of its purification.
Hideyuki Suzuki   +2 more
doaj   +1 more source

Untargeted Metabolomics Uncovers the Essential Lysine Transporter in Toxoplasma gondii

open access: yesMetabolites, 2021
Apicomplexan parasites are responsible for devastating diseases, including malaria, toxoplasmosis, and cryptosporidiosis. Current treatments are limited by emerging resistance to, as well as the high cost and toxicity of existing drugs.
Joachim Kloehn   +4 more
doaj   +1 more source

Organic Cation Transporter 3 (OCT3) Is Localized to Intracellular and Surface Membranes in Select Glial and Neuronal Cells Within the Basolateral Amygdaloid Complex of Both Rats and Mice [PDF]

open access: yes, 2016
Organic cation transporter 3 (OCT3) is a high-capacity, low-affinity transporter that mediates corticosterone-sensitive uptake of monoamines including norepinephrine, epinephrine, dopamine, histamine and serotonin. OCT3 is expressed widely throughout the
Chan, June   +3 more
core   +2 more sources

Control of erythroid differentiation: asynchronous expression of the anion transporter and the peripheral components of the membrane skeleton in AEV- and S13-transformed cells [PDF]

open access: yes, 1986
Chicken erythroblasts transformed with avian erythroblastosis virus or S13 virus provide suitable model systems with which to analyze the maturation of immature erythroblasts into erythrocytes.
Boyer, Brigitte   +3 more
core   +1 more source

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