Results 231 to 240 of about 373,177 (393)

Mutation of Trp1254 in the Multispecific Organic Anion Transporter, Multidrug Resistance Protein 2 (MRP2) (ABCC2), Alters Substrate Specificity and Results in Loss of Methotrexate Transport Activity

, 2001
Ken‐ichi Ito, Curtis Oleschuk, Chris Westlake, Monika Vasa, Roger G. Deeley, Susan P.C. Cole   +5 more
openalex   +1 more source

Bioorthogonal Reaction of o‐Quinone with Furan‐2(3H)‐One for Site‐Selective Tyrosine Conjugation and Construction of Bispecific Antibody Complexes

Advanced Science, EarlyView.
A site‐selective, efficient, and mild tyrosine conjugation via tyrosinase oxidation and nucleophilic addition, allowing for site‐selective functionalization of peptides, recombinant proteins, and IgGs. Site‐selective mono‐functionalization of IgGs at Y296 enables the construction of immunoliposomes.
Hongfei Chen, Zhiyi Xu, Yishu Bao, Farshad Shiri, Dingdong Yuan, Yuke Hu, Biquan Li, Bin Zeng, Xiaojing Li, Hao Kong, Zikang Wang, Wilson Chun‐Yu Lau, Zhenyang Lin, Jiang Xia   +13 more
wiley   +1 more source

Autophagy Regulates Putative Anion Transporter 1 Expression in Intestinal Epithelial Cells. [PDF]

J Cell Mol Med
Priyamvada S, Jayawardena D, Anbazhagan AN, Kumar A, Saksena S, Gill RK, Borthakur A, Alrefai WA, Dudeja PK.   +8 more
europepmc   +1 more source

Salt induced protein dynamics in young rice roots of osmybcc-1 mutant and its involvement in salt stress

Plant Stress
Plants experiencing salt stress often exhibit an ionic homeostasis disorder as a primary symptom. Transcription factor OsMYBc positively regulates OsHKT1;1 to control Na+ accumulation in rice shoots. In this study, root tissues from a T-DNA insert mutant
Rebecca Njeri Damaris, Fengxue Tang, Xiaorong Fan, Zhongming Fang, PingFang Yang, Ming Li   +5 more
doaj  

Interindividual Variability in Hepatic Organic Anion-Transporting Polypeptides and P-Glycoprotein (ABCB1) Protein Expression: Quantification by Liquid Chromatography Tandem Mass Spectroscopy and Influence of Genotype, Age, and Sex [PDF]

, 2013
Bhagwat Prasad, Raymond Evers, Anshul Gupta, Cornelis E. C. A. Hop, Laurent Salphati, Suneet Shukla, Suresh V. Ambudkar, Jashvant D. Unadkat   +7 more
openalex   +1 more source

Camouflaged Nanozymes with Oxidation‐Promoting Activities Triggering Ferroptosis for Radio‐Immunotherapy

Advanced Science, EarlyView.
This study develops a cancer cell membrane‐coated nanozyme that enhances radiotherapy and reshapes the immunosuppressive microenvironment by generating oxygen in situ and disrupting tumor antioxidant defenses, offering a new strategy for breast cancer radioimmunotherapy.
Kun Qiao, Yongbiao Huang, Shipeng Ning, Meng Lyu, Jieqiong Xie, Shiyuan Zhang, Xiuxin Lu, Yuan Yu, Wei Jiang, Bo Liu, Kelong Fan, Tong Liu   +11 more
wiley   +1 more source

The Impact of Organic Anion-Transporting Polypeptide (OATP) Variants on the Side Effects of Direct-Acting Antivirals in Hepatitis C Patients. [PDF]

Cureus
Altintas Z, Altintas E.
europepmc   +1 more source

Protein Kinase C Activation Downregulates Human Organic Anion Transporter 1-Mediated Transport through Carrier Internalization

, 2003
Natascha A. Wolff, Karen M. Thies, N Kuhnke, Glen Reid, Björn Friedrich, Florian Läng, Gerhard Burckhardt   +6 more
openalex   +1 more source

Nedd4-2 but not Nedd4-1 is critical for protein kinase C-regulated ubiquitination, expression, and transport activity of human organic anion transporter 1 [PDF]

, 2016
Da Xu, Haoxun Wang, Qiang Zhang, Guofeng You   +3 more
openalex   +1 more source

Virome and Experimental Analysis Reveal Tryptophan‐Like Dissolved Organic Matter Contributes to the Persistence of Plant Viruses in River Water

Advanced Science, EarlyView.
Tryptophan‐like dissolved organic matter (Try‐like DOM), a key component of organic matter in river ecosystems, demonstrates significant protective effects against plant viruses. The protective mechanism operates via a “swimming firewall” mode, whereby free Try‐like DOM attenuates ultraviolet (UV) radiation and scavenges reactive oxygen species ...
Yujie Wang, Ming Chen, Liu Yang, Jun Ma, Jian Tang, Shengjun Wu, Chi He, J. Paul Chen   +7 more
wiley   +1 more source