Results 241 to 250 of about 3,774,880 (304)

TH/TRs–COL11A2 Axis Mediates Loss of a Differentiated Astrocyte State in Hypogyrified Brains

Advanced Science, EarlyView.
Using a gyrencephalic congenital hypothyroidism pig model, this study reveals cerebral atrophy and cortical hypogyrification. Single‐cell sequencing identifies astrocytes as major TH‐responsive cells, with the COL11A2‐enriched Astro‐2 state nearly absent.
Ying Zhang, Xiao Wang, Hongyan Ma, Pengcheng Lyu, Shuangjie Tian, Ruojun Zong, Jiani Chen, Gang Ren, Yongjiang Yang, Zichen Yang, Guosong Qin, Naishi Li, Yanfang Wang, Jianwei Jiao, Jianguo Zhao   +14 more
wiley   +1 more source

ALMT12: A dual regulator of S-type anion transport in guard cells? [PDF]

Plant Physiol
Xu B.
europepmc   +1 more source

Biomimetic Scaffold‐Based 3D Models for Decoding Cancer Biology and Advancing Therapy

Advanced Science, EarlyView.
A timeline of the research history of 3D biomimetic scaffold materials and platforms. With advances in biomimetic materials and 3D scaffold technologies, their functional scope has expanded from mimicking basic physical and biochemical properties to increasingly replicating complex pathophysiological processes.
Haitao Zhao, Yuechen Han, Jie Li, Peng Luo, Lin Qi, Zhiwei Xia, Xiaosong Li, Quan Cheng, Chenshen Huang, Wantao Wu, Hao Zhang   +10 more
wiley   +1 more source

Putative Modulation of OATP1A2 and P-gp Expression at the Blood-Brain Barrier by Nrf2-PXR: An Associative Hypothesis for Amyloid-β Transport in Alzheimer's Disease. [PDF]

Int J Mol Sci
Li L, Zhang Y, Li S, Zhao M, Hu W, Xiao Y, Wen J.   +6 more
europepmc   +1 more source

Molecular Bases and Genetic Design of Rice Disease Resistance for Optimized Yield and Sustainable Agriculture

Advanced Science, EarlyView.
This study integrates rice immune perception, signal transduction, and resistance output into a multi‐omics framework. By combining high‐throughput sequencing, phenomics, and AI‐assisted design with marker‐assisted selection, gene editing, and rapid domestication, we aim to accelerate the precise breeding of disease‐resistant rice varieties by ...
Xinyue Hou, Yuanjiang Cui, Chaoqing Ding, Qian Qian, Deyong Ren   +4 more
wiley   +1 more source

Genome-wide identification and functional characterization of the Magnesium Transporter (MGT) gene family and its expression patterns to different anionic magnesium stresses in Yinshania henryi. [PDF]

BMC Genomics
Fang H, Duan Y, Li Y, Huang X, Tang J, Zhang X, Yi Y, Tang M.   +7 more
europepmc   +1 more source

A pore is a pore is a pore (or a hub?): VDAC oligomerization in mitochondrial connectivity and modulation. [PDF]

Biochem Soc Trans
De Pinto V, Battiato G, Conti-Nibali S, Cubisino SAM.   +3 more
europepmc   +1 more source

RcAlb-PepII Perturbs the Proteomic Profile of <i>Cryptococcus neoformans</i>, Shutting Down Proteins Involved in Fungal Survival. [PDF]

Microorganisms
Filho NSDS, Silva L, Cordeiro RA, Lima PG, Neto NADS, Lima PVDR, Gomes FIR, Mororó JLT, Filho JHA, Mesquita FP, Souza PFN.   +10 more
europepmc   +1 more source

The effects of androgens on drug metabolism and transport: clinical pharmacologic considerations for people assigned female at birth. [PDF]

Expert Opin Drug Metab Toxicol
Hunter MJ, Cirrincione LR.
europepmc   +1 more source

Selectivity of OATs and OATPs for Endogenous Metabolites and Signaling Molecules <i>In Vivo</i>. [PDF]

ACS Omega
Nigam AK, Falah K, Momper JD, Nigam SK.
europepmc   +1 more source