Results 231 to 240 of about 80,553 (266)

Fluorescent stilbene (BADS) binding proteins in anion-transporting epithelia

American Journal of Physiology-Cell Physiology, 1990
Chloride transport occurs at the interface between the internal and external environments of a cell where chloride uptake or efflux is regulated through a variety of mechanisms that involve cotransport of cations, exchange mechanism with anions, or movement through channels.
S F, Pearce, J A, Zadunaisky
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Anion transport in relation to proteolytic dissection of band 3 protein

Biochimica et Biophysica Acta (BBA) - Biomembranes, 1978
Sulfate efflux was measured in inside-out vesicles obtained from human red cells. Inhibition was observed in vesicles derived from cells pretreated with DIDS (4,4'-diisothiocyano-2,2'-stilbene disulfonate) or after addition of dipyridamole to the vesicles, both agents being specific and potent inhibitors of anion transport in cells.
S, Grinstein, S, Ship, A, Rothstein
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Transepithelial Transport of Organic Anions across the Choroid Plexus: Possible Involvement of Organic Anion Transporter and Multidrug Resistance-Associated Protein

The Journal of Pharmacology and Experimental Therapeutics, 1999
Transport characteristics of 17beta-estradiol 17beta-D-glucuronide (E217betaG), a dual substrate of the transporters for cellular uptake (organic anion-transporting polypeptide 1 or oatp1) and cellular excretion (multidrug resistance-associated protein 1or MRP1), in the rat choroid plexus were studied in vivo and in vitro.
J, Nishino, H, Suzuki, D, Sugiyama, T, Kitazawa, K, Ito, M, Hanano, Y, Sugiyama   +6 more
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Macromolecular conjugates of transport inhibitors: new tools for probing topography of anion transport proteins

American Journal of Physiology-Cell Physiology, 1991
Macromolecular-conjugated, water-soluble, membrane-impermeant compounds were designed and assessed as topological probes for chloride-transporting agencies. The novel compounds were derivatives of either disulfonic stilbene (DS) and benzylaminoethylsulfonate (BS), "classical" inhibitors of erythrocyte chloride-bicarbonate exchange, or of ...
O, Eidelman, P, Yani, H C, Englert, H G, Lang, R, Greger, Z I, Cabantchik   +5 more
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Structure and Function of the Red Blood Cell Anion Transport Protein

Annual Review of Biophysics and Biophysical Chemistry, 1989
PHYSIOLOGICAL FUNCTION . Role of Chloride-Bicarbonate Exchange in Carbon Dioxide Transport .. Other Substrates of Red Cell Band 3 . . Transport Functions Other Than Anion Exchange . . Band 3 Homologs in Nonerythroid Cells ..
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Asymmetry of functional sites of the erythrocyte anion transport protein

Trends in Biochemical Sciences, 1978
The accessibility of functional sites of the anion transport system of the red blood cell to inhibitory probes differs depending on the side of the membrane to which they are applied. These effects are discussed in terms of the asymmetric arrangement of the transport protein, Band 3, in the membrane.
A. Rothstein, S. Grinstein, S. Ship, P.A. Knauf   +3 more
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Immunologic distribution of an organic anion transport protein in rat liver and kidney

American Journal of Physiology-Gastrointestinal and Liver Physiology, 1996
A Na(+)-independent organic anion transport protein was recently cloned from rat liver using a Xenopus laevis oocyte expression system [E. Jacquemin, B. Hagenbuch, B. Stieger, A.W. Wolkoff, and P.J. Meier, Proc. Natl. Acad. Sci. USA 91: 133-137, 1994].
Bergwerk, A. J., Shi, X., Ford, A. C., Kanai, N., Jacquemin, E., Burk, R. D., Bai, S., Novikoff, P. M., Stieger, B., Meier, P. J., Schuster, V. L., Wolkoff, A. W.   +11 more
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Interaction of phloretin with the anion transport protein of the red blood cell membrane

Biochimica et Biophysica Acta (BBA) - Biomembranes, 1982
Phloretin is an inhibitor of anion exchange and glucose and urea transport in human red cells. Equilibrium binding the kinetic studies indicate that phloretin binds to band 3, a major integral protein of the red cell membrane. Equilibrium phloretin binding has been found to be competitive with the binding of the anion transport inhibitor, 4,4 ...
S A, Forman, A S, Verkman, J A, Dix, A K, Solomon   +3 more
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Computational Analysis of Organic Anion Transport Proteins

2020
This project will use ancestral sequence reconstruction and computational modeling to inform the design of novel function in human OATP proteins with the dual goal of enhanced uptake of MRI contrast agents and non-immunogenic properties. These new functions will allow cells introduced into the body, such as stem cells or immunotherapies to be ...
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Dichotomous development of the organic anion transport protein in liver and choroid plexus

American Journal of Physiology-Cell Physiology, 1998
Both adult liver and choroid plexus express the organic anion transport protein (oatp1) and transport [35S]bromosulfophthalein (BSP). Studies of the developing rat liver reveal that oatp1 mRNA and protein do not begin to be expressed until 15 days postnatal and are at adult levels by 30 days. Uptake of [35S]BSP follows the same time course.
R H, Angeletti, A J, Bergwerk, P M, Novikoff, A W, Wolkoff   +3 more
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