Results 151 to 160 of about 53,461 (270)

Serious Infection in Crohn's Disease Patients Treated With Ustekinumab: US Food and Drug Administration Active Postmarket Risk Identification and Analysis in the Sentinel Initiative

Clinical Pharmacology &Therapeutics, Volume 119, Issue 6, Page 1514-1521, June 2026.
The U.S. Food and Drug Administration (FDA) used an Active Postmarket Risk Identification and Analysis (ARIA) system to address a safety issue (serious infection) identified during clinical review of an application to market ustekinumab as a treatment for Crohn's disease (CD). FDA used an active‐comparator new‐user cohort design, data from six Sentinel
Joel L. Weissfeld, Geetha S. Iyer, Suna C. Seo, Andrew Giffin, Andrew L. Simon, Sheryl A. Kluberg, Emma R. Hoffman, Jamal T. Jones, Sarah K. Dutcher, Joyce A. Korvick   +9 more
wiley   +1 more source

Bone Mineral Density in Ankylosing Spondylitis

, 2003
Ankylosing Spondylitis (AS), a chronic inflammatory rheumatic disease. One of the most frequent and important complications in these patients is osteoporosis.
Hidayet Sarı, Bahar Çakmak
core  

Ankylosing spondylitis. [PDF]

BMJ, 1962
openaire   +3 more sources

The Role of Endothelin‐1 in Autoimmune Diseases: Mechanistic Insights and Therapeutic Targets

iNew Medicine, Volume 2, Issue 2, June 2026.
The Role of Endothelin‐1 in Autoimmune Diseases. NF‐κB: nuclear factor kappa‐B; MAPK: mitogen‐activated protein kinase; PI3K: phosphoinositide 3‐kinase; ROS: reactive oxygen species; CTGF: connective tissue growth factor; TGF‐β: transforming growth factor‐β.
Xun Gong, Zhenyu Wang, Suyin Yang, Kaige Gao, Xin Yang, Min Tang   +5 more
wiley   +1 more source

Synovial Fluid Biomarkers Reflect Pre‐ and Postoperative Clinical Features in Rotator Cuff Tears, Independent of Tear Size

Journal of Orthopaedic Research, Volume 44, Issue 6, June 2026.
ABSTRACT Synovitis is a major contributor to pain and dysfunction in rotator cuff tears (RCTs), yet it remains unclear whether routine synovial fluid (SF) parameters reflect clinical features independent of tear size, operation method, and patient age.
Seungmin Jeong, Jong Min Lee, Jeong‐Hyun Koh, Doohyung Lee   +3 more
wiley   +1 more source

Patients With Chronic Low Back Pain Without Advanced Disk Degeneration Exhibit Gut Microbiome Dysbiosis: Evidence From an Age‐, Sex‐, and BMI‐Matched Pilot Study

JOR SPINE, Volume 9, Issue 2, June 2026.
Chronic low back pain in patients without advanced disc degeneration is associated with gut microbiome dysbiosis, marked by reduced microbial diversity and altered bacterial composition. These findings support a gut–disk axis in which impaired gut barrier integrity and systemic inflammation may contribute to disc inflammation, nociceptive fiber ...
Stone Sima, Thomas Jeffries, Alisha Sial, Suhani Sharma, Neha Chopra, Fan Zhang, Georgina Hold, Wentian Li, Ji Tu, Victor Chen, Ashish Diwan   +10 more
wiley   +1 more source

Lateral Decubitus Transradial Carotid Artery Stenting in Ankylosing Spondylitis: A Novel Positioning Strategy. [PDF]

Am J Case Rep
Tang W, Liu J.
europepmc   +1 more source

Explainable Supervised Learning Classification Model Using Diffusion Tensor Imaging Predicts Postoperative Outcomes in Cervical Spondylotic Myelopathy: A Preliminary Study

JOR SPINE, Volume 9, Issue 2, June 2026.
ABSTRACT Background Cervical spondylotic myelopathy (CSM) is common in older adults. Some patients may experience incomplete neurological recovery after surgery, or even deterioration. Accurate prognosis is essential for patients, yet current tools use subjective scores and fail to detect early spinal cord microstructural changes.
Yifei Peng, Zixuan Zhang, Zhikun Zhang, Kaiyi Shi, Ruoyu Wang, Yue Liu, Li Zhang   +6 more
wiley   +1 more source

Fat infiltration is moderately associated with disease activity in ankylosing spondylitis: a cross-sectional study: Lumbar paraspinal muscles in ankylosing spondylitis. [PDF]

Medicine (Baltimore)
Toprak M, Toprak N.
europepmc   +1 more source

Clinical Features and Therapeutic Outcomes in Pyoderma Gangrenosum: A Prospective Cohort Study

JEADV Clinical Practice, Volume 5, Issue 2, Page 495-501, June 2026.
ABSTRACT Background Pyoderma gangrenosum (PG) is a rare neutrophilic dermatosis highly associated with systemic comorbidities. Accurate diagnosis and treatment remain challenging due to its rarity and clinical mimickers. Objectives To evaluate demographic, clinical features and treatment outcomes in patients referred with suspected PG at a tertiary ...
David Croitoru, Nesrine Brahimi, Haleh Zabihi, Cathryn Sibbald, Kyle Seigel, Delaram Shojaei, Eric McMullen, Afsaneh Alavi, Lily Archaempong, Aaron M. Drucker, Adam Weizman, Kenneth Croitoru, Robert Inman, Vincent Piguet   +13 more
wiley   +1 more source