Results 171 to 180 of about 58,843 (270)

Comparative Safety Analysis of Targeted Synthetic and Biologic Disease‐Modifying Antirheumatic Drugs Among Patients With Rheumatoid Arthritis: A Nationwide Cohort Study in Japan

open access: yesInternational Journal of Rheumatic Diseases, Volume 29, Issue 9, September 2026.
ABSTRACT Aim To compare risks of malignancy, opportunistic infections, and venous thromboembolism between the targeted synthetic disease‐modifying antirheumatic drugs (tsDMARDs) and biologic DMARDs (bDMARDs) at the 2nd and 3rd lines of therapy (LOT). Methods We conducted a cohort study using the National Database of Health Insurance Claims (2013–2021).
Shiori Nishimura   +13 more
wiley   +1 more source

Biologic and targeted synthetic therapies in ankylosing spondylitis: a pharmacological review. [PDF]

open access: yesFront Pharmacol
Ameer OZ   +5 more
europepmc   +1 more source

Online Andrology: Real‐World Status Quo of Patients’ Online Information Sources and Comparison With Large Language Models in Germany

open access: yesAndrology, Volume 14, Issue 6, Page 1823-1830, September 2026.
ABSTRACT Background The internet, including websites and large language models (LLMs), is an increasingly important information resource for medical patients. However, information quality varies, potentially leading to misinformation. Andrological patients may particularly rely on online sources due to the sensitive nature of their conditions ...
Traeger Max   +7 more
wiley   +1 more source

Targeting m6A Modifications Regulating Ferroptosis Offers Novel Therapy in Diseases

open access: yesCell Proliferation, Volume 59, Issue 9, September 2026.
m6A RNA modification regulates ferroptosis by balancing iron metabolism, lipid peroxidation, and antioxidant defenses. Dysregulated m6A signaling disrupts pro‐ and anti‐ferroptotic factors, leading to excess ROS, Fe3+ accumulation, and lipid peroxidation–driven cell death. Targeting m6A‐mediated ferroptotic regulation represents a promising therapeutic
Lida Du   +7 more
wiley   +1 more source

Impact of socioeconomic status on disability in a longitudinal rheumatoid arthritis cohort

open access: yesInternal Medicine Journal, Volume 56, Issue 9, Page 1644-1648, September 2026.
Abstract The impact of socioeconomic status (SES) on health outcomes in Australians living with rheumatoid arthritis (RA) is not known. We aimed to determine whether differences in disability trajectory were present according to individuals' SES using longitudinal data from the Australian Rheumatology Association Database.
Oscar Russell   +9 more
wiley   +1 more source

Mapping the Altered Landscape of TCR Repertoire in Autoimmune Diseases

open access: yesImmunological Reviews, Volume 342, Issue 1, September 2026.
ABSTRACT Autoimmune diseases arise from the breakdown of immune tolerance through complex interactions between genetic predisposition, environmental exposures, and adaptive immune responses. High‐throughput T‐cell receptor (TCR) repertoire sequencing has transformed our ability to characterize these responses, providing unprecedented insights into ...
Celine Albalaa   +3 more
wiley   +1 more source

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