Results 171 to 180 of about 58,843 (270)
ABSTRACT Aim To compare risks of malignancy, opportunistic infections, and venous thromboembolism between the targeted synthetic disease‐modifying antirheumatic drugs (tsDMARDs) and biologic DMARDs (bDMARDs) at the 2nd and 3rd lines of therapy (LOT). Methods We conducted a cohort study using the National Database of Health Insurance Claims (2013–2021).
Shiori Nishimura +13 more
wiley +1 more source
Biologic and targeted synthetic therapies in ankylosing spondylitis: a pharmacological review. [PDF]
Ameer OZ +5 more
europepmc +1 more source
ABSTRACT Background The internet, including websites and large language models (LLMs), is an increasingly important information resource for medical patients. However, information quality varies, potentially leading to misinformation. Andrological patients may particularly rely on online sources due to the sensitive nature of their conditions ...
Traeger Max +7 more
wiley +1 more source
A Rigid Spine at Risk: Chalk-Stick Fracture With Dural Sac Entrapment After Ground-Level Fall. [PDF]
Wetzel DJ, Nguyen LN, Wrubel GL.
europepmc +1 more source
Targeting m6A Modifications Regulating Ferroptosis Offers Novel Therapy in Diseases
m6A RNA modification regulates ferroptosis by balancing iron metabolism, lipid peroxidation, and antioxidant defenses. Dysregulated m6A signaling disrupts pro‐ and anti‐ferroptotic factors, leading to excess ROS, Fe3+ accumulation, and lipid peroxidation–driven cell death. Targeting m6A‐mediated ferroptotic regulation represents a promising therapeutic
Lida Du +7 more
wiley +1 more source
Trigger finger and the risk of systemic inflammatory and autoimmune rheumatic diseases: real-world evidence. [PDF]
Lin ZH +4 more
europepmc +1 more source
Impact of socioeconomic status on disability in a longitudinal rheumatoid arthritis cohort
Abstract The impact of socioeconomic status (SES) on health outcomes in Australians living with rheumatoid arthritis (RA) is not known. We aimed to determine whether differences in disability trajectory were present according to individuals' SES using longitudinal data from the Australian Rheumatology Association Database.
Oscar Russell +9 more
wiley +1 more source
Changing Patterns of Hospitalisation and Orthopaedic Procedure Profiles in Major Inflammatory Rheumatic Diseases in Germany: a Nationwide Analysis of Hospital Discharge Data. [PDF]
Anees H +4 more
europepmc +1 more source
Mapping the Altered Landscape of TCR Repertoire in Autoimmune Diseases
ABSTRACT Autoimmune diseases arise from the breakdown of immune tolerance through complex interactions between genetic predisposition, environmental exposures, and adaptive immune responses. High‐throughput T‐cell receptor (TCR) repertoire sequencing has transformed our ability to characterize these responses, providing unprecedented insights into ...
Celine Albalaa +3 more
wiley +1 more source

