Results 121 to 130 of about 136,777 (328)

OSTEOPOROSIS IN PATIENTS WITH ANKYLOSING SPONDYLITIS

Фундаментальная и клиническая медицина, 2019
Currently, rheumatologists consider osteoporosis as a complication of ankylosing spondylitis, however, in recent years, it is discussed as a comorbidity but not a complication.
TATIANA A. Raskina, OLGA S. Malyshenko, OKSANA A. Pirogova, INESSA I. Grigorieva   +3 more
doaj  

Ankylosing spondylitis risk factors: a systematic literature review

Clinical Rheumatology, 2021
M. Hwang, Lauren K Ridley, J. Reveille
semanticscholar   +1 more source

Impact of Tumor Necrosis Factor Inhibitor Versus Nonsteroidal Antiinflammatory Drug Treatment on Radiographic Progression in Early Ankylosing Spondylitis: Its Relationship to Inflammation Control During Treatment

Arthritis & Rheumatology, 2018
To investigate the impact of tumor necrosis factor inhibitor (TNFi) treatment and inflammation control on radiographic progression in early ankylosing spondylitis (AS) over 4 years.
Jun Won Park, Min Jung Kim, J. Lee, Y. Ha, J. Park, E. Kang, Y. Lee, Y. Song, E. Lee   +8 more
semanticscholar   +1 more source

Role of HLA-B27 in the pathogenesis of ankylosing spondylitis

Molecular Medicine Reports, 2017
The study of ankylosing spondylitis (AS) has made significant progress over the last decade. Genome-wide association studies have identified and further substantiated the role of susceptibility genes outside the major histocompatibility complex locus ...
Bin Chen, Jia Li, Chong-ru He, Dahe Li, W. Tong, Yuming Zou, Weidong Xu   +6 more
semanticscholar   +1 more source

Effects of psoriatic arthritis‐targeted drugs on bone remodeling: Clinical evidence and molecular pathways

Rheumatology &Autoimmunity, EarlyView.
Mechanisms and therapeutic targets in psoriatic arthritis: balancing inflammatory bone resorption and bone formation. Abstract Psoriatic arthritis (PsA) is a chronic inflammatory disease characterized by diverse clinical manifestations. Of particular concern, osteopenia and osteoporosis are prevalent in 45.27% and 12.94% of PsA patients, respectively ...
Yingchao Sun, Cheng Xu, Mingli Ouyang, Yongmei Han   +3 more
wiley   +1 more source

ERAP1 and ankylosing spondylitis

Current Opinion in Immunology, 2013
The strong genetic association of ERAP1 (endoplasmic reticulum aminopeptidase 1) with ankylosing spondylitis (AS), which is restricted to HLA-B27 positive cases, has profound pathogenetic implications. ERAP1 is involved in trimming peptides to optimal length for binding to HLA class 1 molecules, thereby not only affecting the stability and processing ...
Keidel, S, Chen, L, Pointon, J, Wordsworth, B   +3 more
openaire   +4 more sources

Comparative Effectiveness and Safety of Adalimumab, Secukinumab, and Upadacitinib in Psoriatic Arthritis: A Prospective Cohort Study Based on PARWCH Cohort

The Journal of Dermatology, EarlyView.
ABSTRACT Psoriatic arthritis (PsA) is a chronic inflammatory disease, with prevalence among psoriasis patients ranging from 6% to 42% across populations. Although targeted therapies such as adalimumab (ADA), secukinumab (SEC), and upadacitinib (UPA) have demonstrated efficacy in randomized controlled trials, real‐world head‐to‐head comparisons remain ...
Yiyi Wang, Jingya Gao, Furong Li, Luyuan Li, Yue Xiao, Hongxiang Hu, Xiya Peng, Min Yang, Dan Hao, Wei Yan, Dengmei Xia, Wei Li   +11 more
wiley   +1 more source

Surgical anesthesia with a combination of T12 paravertebral block and lumbar plexus, sacral plexus block for hip replacement in ankylosing spondylitis: CARE-compliant 4 case reports

BMC Anesthesiology, 2017
Background Anesthesia management for patients with severe ankylosing spondylitis scheduled for total hip arthroplasty is challenging due to a potential difficult airway and difficult neuraxial block.
Xijian Ke, Ji Li, Yong Liu, Xi Wu, Wei Mei   +4 more
doaj   +1 more source

HLA-B27 Positivity: associated health implications [PDF]

, 2011
HLA-B27 positivity makes the onset of autoimmune diseases such as uveitis, ankylosing spondylitis and Crohn's disease more likely to occur. Ankylosing spondylitis and Crohn's disease are two types of HLA-B27 positive diseases that demonstrate a direct ...
Cox, C. L., Evans, P., Gibbons, H., Titmus, K., Withers, T.   +4 more
core   +1 more source

Effect of secukinumab on clinical and radiographic outcomes in ankylosing spondylitis: 2-year results from the randomised phase III MEASURE 1 study

Annals of the Rheumatic Diseases, 2016
Objective To evaluate the effect of secukinumab, an interleukin-17A inhibitor, on clinical signs and symptoms and radiographic changes through 2 years in patients with ankylosing spondylitis (AS).
J. Braun, X. Baraliakos, A. Deodhar, D. Baeten, J. Sieper, P. Emery, A. Readie, R. Martin, S. Mpofu, H. Richards   +9 more
semanticscholar   +1 more source