Results 201 to 210 of about 41,338 (239)

Superfamily of ankyrin repeat proteins in tomato

Gene, 2013
The ankyrin repeat (ANK) protein family plays a crucial role in plant growth and development and in response to biotic and abiotic stresses. However, no detailed information concerning this family is available for tomato (Solanum lycopersicum) due to the limited information on whole genome sequences.
Xiaowei, Yuan, Shizhong, Zhang, Xiaohe, Qing, Meihong, Sun, Shiyang, Liu, Hongyan, Su, Huairui, Shu, Xinzheng, Li   +7 more
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Functional role of proteins containing ankyrin repeats

Cell and Tissue Biology, 2008
This review describes and discusses new data about the structure and function of proteins which contain ankyrin-like repeats in their structure. These proteins have been found in cells of different organisms but they are not belonging to the cytoskeletal proteins.
D A, Voronin, E V, Kiseleva
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Two C-terminal ankyrin repeats form the minimal stable unit of the ankyrin repeat protein p18INK4c

Journal of Molecular Modeling, 2008
Ankyrin repeat proteins (ARPs) appear to be abundant in organisms from all phyla, and play critical regulatory roles, mediating specific interactions with target biomolecules and thus ordering the sequence of events in diverse cellular processes. ARPs possess a non-globular scaffold consisting of repeating motifs named ankyrin (ANK) repeats, which ...
Petr, Sklenovský, Pavel, Banás, Michal, Otyepka   +2 more
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Development of LRRK2 designed ankyrin-repeat proteins

2023
AbstractLeucine rich repeat kinase 2 (LRRK2) is a large multidomain protein containing two catalytic domains, a kinase and a GTPase, as well protein interactions domains, including a WD40 domain. The association of increased LRRK2 kinase activity with both the familial and sporadic forms of Parkinson’s disease (PD) has led to intense interest in ...
Verena Dederer, Marta Sanz Murillo, Eva P Karasmanis, Kathryn S Hatch, Deep Chatterjee, Franziska Preuss, Kamal R Abdul Azeez, Landon Vu Nguyen, Christian Galicia, Birgit Dreier, Andreas Plückthun, Wim Versees, Sebastian Mathea, Andres E Leschziner, Samara L Reck-Peterson, Stefan Knapp   +15 more
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Novel actions of cardiac ankyrin repeat protein

International Congress Series, 2007
Abstract Gene expression profiling of mouse skin wounds has led to the discovery of numerous target genes that may have therapeutic or diagnostic value. Cardiac ankyrin repeat protein (CARP, ankrd1 ) expression is markedly and persistently elevated in cutaneous wounds. This article provides a summary and perspective on CARP with particular reference
Susan E. Samaras, Yubin Shi, Jeffrey M. Davidson   +2 more
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Biophysical Characterisation of the Small Ankyrin Repeat Protein Myotrophin

Journal of Molecular Biology, 2007
The 118 residue protein myotrophin is composed of four ankyrin repeats that stack linearly to form an elongated, predominantly alpha-helical structure. The protein folds via a two-state mechanism at equilibrium. The free energy change of unfolding in water (DeltaG(U-N)(H(2)O)) is 5.8 kcal.mol(-1).
Alan R, Lowe, Laura S, Itzhaki
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A New Role for Ankyrin Repeats

Science's STKE, 2007
Transient receptor potential (TRP) channels are nonselective cation channels that act as sensors of heat and noxious chemicals and thus are important in pain perception. One member of this family, TRPV1, responds to such stimuli as heat, low pH, and capsaicin, the ingredient of chili peppers that makes them "hot." Two mechanisms are known ...
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Ankyrin‐repeat proteins from sponge symbionts modulate amoebal phagocytosis

Molecular Ecology, 2013
AbstractBacteria–eukaryote symbiosis occurs in all stages of evolution, from simple amoebae to mammals, and from facultative to obligate associations. Sponges are ancient metazoans that form intimate symbiotic interactions with complex communities of bacteria. The basic nutritional requirements of the sponge are in part satisfied by the phagocytosis of
Mary T H D, Nguyen, Michael, Liu, Torsten, Thomas   +2 more
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Methyl-Lysine Recognition by Ankyrin-Repeat Proteins

2015
The ankyrin repeats (ANKs) of the methyltransferases G9a and GLP bind methyllysine (meK) in a surface aromatic cage. Binding the methylation product with the very same polypeptide that generates it seems essential for some G9a/GLP functions, but it is dispensable for others.
Robert E. Collins, Xiaodong Cheng
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Ankyrin repeat-containing N-Ank proteins shape cellular membranes

Nature Cell Biology, 2019
Cells of multicellular organisms need to adopt specific morphologies. However, the molecular mechanisms bringing about membrane topology changes are far from understood-mainly because knowledge of membrane-shaping proteins that can promote local membrane curvatures is still limited.
David Wolf, Sarah Ann Hofbrucker-MacKenzie, Maryam Izadi, Eric Seemann, Frank Steiniger, Lukas Schwintzer, Dennis Koch, Michael Manfred Kessels, Britta Qualmann   +8 more
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