Results 231 to 240 of about 202,359 (295)

Ultrasound‐Activated Nanoinhibitors Blocking the Chemo‐Immune Checkpoint to Overcome Chemotherapy‐Induced Immune Resistance

Advanced Science, EarlyView.
A sono‐responsive chemo‐immune checkpoint nanoinhibitor (Sono‐TT8) co‐delivering TPZ chemotherapy and siXkr8 simultaneously kills tumor cells and blocks PS externalization, reversing chemotherapy‐induced immunosuppression and enhancing antitumor immunity. ABSTRACT Breast cancer features an immunosuppressive tumor microenvironment following chemotherapy
Yunfan Liu, Chier Du, Leilei Zhu, Hongjin An, Shengzhe Hou, Yi Lan, Xuemei Tang, Min Xu, Peng Luo, Hua Teng, Hao Yang, Xun Guo, Jianli Ren, Zhiyi Zhou   +13 more
wiley   +1 more source

Human Histatin 5 Exerts Anti-Trypanosomal Activity Against <i>Trypanosoma cruzi</i> and Induces Ultrastructural Damage, Apoptosis-like Cell Death, and Oxidative/Nitrosative Stress. [PDF]

Int J Mol Sci
Blancas-Luciano BE, Becker I, Sánchez-Chávez MA, Gómez-Guzmán A, Lara-Martínez R, Jiménez-García LF, Zamora-Chimal J, Delgado-Dominguez J, Fernández-Presas AM.   +8 more
europepmc   +1 more source

An Unbiased Geometry‐Resolved Membrane Platform for Proteome‐Scale Discovery of Membrane Curvature Sensors

Advanced Science, EarlyView.
A novel geometry‐resolved membrane platform provides a seamlessly integrated pipeline for studying curvature‐sensing proteins. By linking shotgun proteomics with quantitative imaging, this approach enables both the unbiased discovery and rigorous validation of novel sensors across the entire curvature range—positive, negative, and zero.
Takumi Komikawa, Rikuto Kawakami, Kunanon Chattrairat, Tatsuya Niwa, Taiga Ajiri, Takao Yasui, Masayoshi Tanaka   +6 more
wiley   +1 more source

Annexin A2 associated with bevacizumab resistance and infiltrative escape in glioblastoma. [PDF]

J Neurooncol
Ezaki T, Tamura R, Yamamoto Y, Takei J, Teshigawara A, Tomoto K, Akasaki Y, Murayama Y, Toda M, Sasaki H, Miyake K, Tanaka T.   +11 more
europepmc   +1 more source

Helicobacter pylori‐Induced Persistent IGF2BP1 Activation Promotes Ferroptosis Resistance in Gastric Tumorigenesis

Advanced Science, EarlyView.
Helicobacter pylori infection induces sustained upregulation of the RNA‐binding protein IGF2BP1 in gastric epithelial cells, establishing a persistent epitranscriptomic program. IGF2BP1 stabilizes SLC7A11 mRNA in an m6A‐dependent manner to suppress ferroptosis and promote epithelial survival under oxidative stress. Pharmacological inhibition of IGF2BP1
Jing Ning, Xin Guan, Xinyu Hao, Jing Zhang, Deyao Li, Ying Xiong, Wenlin Zhang, Xiurui Han, Yanfei Lang, Meiling Zhou, Mengjie Yang, Zhi Huang, Tinghui Qu, Ming Zu, Qiao Meng, Weiwei Fu, Fengmin Lu, Jing Zhang, Xiangmei Chen, Tong Liu, Shigang Ding   +20 more
wiley   +1 more source

DRAQ7 overcomes the complications associated with autofluorescence of doxorubicin during flow cytometric analyses. [PDF]

Biol Methods Protoc
Çiftçi YC, Erdoğan Vatansever İ, Akgül B.   +2 more
europepmc   +1 more source

Effects of triethylene glycol dimethacrylate and bisphenol A-glycidyl methacrylate on annexin A proteins in human mesangial cells. [PDF]

Eur J Oral Sci
Doğan AN, Bala N, Shahzad Z, Galban ES, Alli AA.   +4 more
europepmc   +1 more source

Redistribution of peripheral blood immune cell subsets and remodeling of intercellular communication in rare Behçet's disease: a single-cell transcriptomics study. [PDF]

Front Med (Lausanne)
Yang Y, Chen Y.
europepmc   +1 more source

Salvianolic Acid a Disrupts the HSP90α-AKT-PERK Ternary Complex to Alleviate Atherosclerosis by Activating Endoplasmic Reticulum Stress of Senescent Vascular Smooth Muscle Cells. [PDF]

Adv Sci (Weinh)
Guan X, Lu M, Cui X, Zhang D, Zhang L, Lin L, Li Y, Hu Y, Li C.   +8 more
europepmc   +1 more source

Nucleolin Alterations and ROS Production Associate With Sensitivity of AML Cells to Venetoclax. [PDF]

FASEB J
Wolfová K, Otevřelová P, Brodská B.
europepmc   +1 more source