Results 171 to 180 of about 6,682 (198)

Annexin A5: an imaging biomarker of cardiovascular risk

Basic Research in Cardiology, 2008
Apoptosis, a form of programmed cell death (PCD), plays an important role in the initiation and progression of a number of cardiovascular disease, such as heart failure, myocardial infarction, and atherosclerosis. One of the most prominent characteristics of apoptosis is the externalisation of phosphatidylserine (PS), a plasma cell membrane ...
Edward M, Laufer, Chris P M, Reutelingsperger, Jagat, Narula, Leonard, Hofstra   +3 more
openaire   +2 more sources

Immunohistochemical expression of Annexin A5 in preeclamptic placentas

Placenta, 2011
To study the expression of Annexin A5 (A5) in relation to preeclampsia using immunohistochemical Tissue Microarray (TMA) technique.Case-control study of 66 singleton preeclamptic (PE) patients matched for gestational age (GA) at delivery with 63 normotensive controls with normally grown fetuses. Immunohistochemical expression of A5 and other population
ORNAGHI, SARA, VERGANI, PATRIZIA, URBAN, GABRIELE, GIARDINI, VALENTINA, MOLTRASIO, FRANCESCA, LEONE, BIAGIO EUGENIO   +5 more
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Annexin A5 suppression promotes the progression of cervical cancer

Archives of Gynecology and Obstetrics, 2022
Cervical cancer is a common malignant gynecological disease that threatens the health of women all over the world. The abnormal expression of Annexin A5 (ANXA5) is closely related to the biological behavior of various malignant tumors, however, the relationship between ANXA5 and cervical cancer is still unclear. Therefore, the effects of low expression
Xiaojie Wang, Yarui Dai, Jialu Zhang, Xin Li   +3 more
openaire   +2 more sources

The −1C>T mutation in the annexin A5gene does not affect plasma levels of annexin A5

Blood, 2003
Gonzalez-Conejero and coworkers describe how the −1C>T mutation, located in the Kozak sequence of the annexin A5 gene (formerly named annexin V), reduced the risk of myocardial infarction in young patients.[1][1] They postulated and showed supporting evidence that −1C>T in the Kozak sequence ...
Heerde, W.L. van, Kenis, H., Schoormans, S.C.M., Lap, P., Reutelingsperger, C.P.M.   +4 more
openaire   +3 more sources

Annexin-A5 and membrane repair in the placenta

Placenta, 2014
s / Placenta 35 (2014) A1eA112 A5 PL3.2. MIRNA NANO-PACKAGES FOR MATERNAL-PLACENTAL-FETAL COMMUNICATION Yingshi Ouyang , Jean-Francois Mouillet , Guojing Chang , Tianjiao Chu , Elena Sadovsky , Avraham Bayer , Takuya Mishima , Carolyn Coyne , Yoel Sadovsky a,b Magee-Womens Research Institute, University of Pittsburgh Dept of OBGYN-Reproductive Sciences,
Alain Brisson, Anthony Bouter, Romain Carmeille, Sisareuth Tan, Celine Gounou, Severine Degrelle, Guillaume Pidoux, Daniele Evain-Brion   +7 more
openaire   +1 more source

Eukaryotic expression and secretion of EGFP-labeled annexin A5

Protein Expression and Purification, 2008
The Ca2+-dependent binding of annexin A5 to phosphatidylserine on cell surfaces is a reliable marker for apoptosis that is widely used in flow cytometry based apoptosis assays. In this approach, annexin A5 must be coupled to a fluorescent dye, but standard dyes such as fluorescein are photolabile, and the heterogeneous chemical linkage partially ...
Michael, Stöcker, Alessa, Pardo, Christian, Hetzel, Chris, Reutelingsperger, Rainer, Fischer, Stefan, Barth   +5 more
openaire   +2 more sources

Annexin A5 Protein as a Potential Biomarker for the Diagnosis of Asthma

Lung, 2018
Annexin A5 (ANXA5) has a potential role in cellular signal transduction, inflammation, and fibrosis. However, the exact role of ANXA5 in asthma remains to be clarified. The aims of the present study were to investigate ANXA5 protein expression in a mouse model of asthma and pollutant exposure and to elucidate the relationships between clinical ...
Sun-Hye Lee, Pureun-Haneul Lee, Byeong-Gon Kim, Jisu Hong, An-Soo Jang   +4 more
openaire   +2 more sources

Effect of lipoprotein (a) on annexin A5 binding to cell membrane

Clinica Chimica Acta, 2010
High blood lipoprotein (a) [Lp(a)] concentration is a risk factor for a thrombotic event. Annexin A5 is involved in anticoagulation on the endothelial surface. How Lp(a) affects the annexin A5 function is not clear. This study investigates annexin A5 binding on the cell membrane in the presence of Lp(a).Lp(a) was isolated from human blood plasma by ...
Yi-Chi, Fu, Jen-Tsung, Yang, Hui-Wen, Chen, June Hsieh, Wu   +3 more
openaire   +2 more sources

Annexin A5 Multitasking: A Potentially Novel Antiatherothrombotic Agent?

Drug News & Perspectives, 2007
Atherothrombosis, formed on an underlying atherosclerotic plaque, is the key pathogenic mechanism behind the majority of clinically evident cardiovascular ischemic diseases including acute coronary artery disease, cerebrovascular and peripheral arterial occlusion.
Anna, Cederholm, Johan, Frostegård
openaire   +2 more sources

Assessment of annexin A5 and annexin A2 levels as biomarkers for pre-eclampsia: A pilot study

Pregnancy Hypertension: An International Journal of Women's Cardiovascular Health, 2017
Deficient anticoagulant activity of annexin A5 and deficient profibrinolytic activity of annexin A2 have been linked to increased risk of thrombotic events. Placental dysfunction due to fibrin deposition/microthrombi has been implicated in the pathogenesis of pre-eclampsia (PE).
Marwa, Abd El-Latif, Hanan, Azzam, Maha, Othman, Osama, Warda, Solafa, El-Sharawy, Hayam, Ghoneim   +5 more
openaire   +2 more sources