Results 91 to 100 of about 3,398,936 (266)
CEACAM1 participation in breast cancer progression
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
The Mortara Center for International Studies Annual Report 2010-2011
Annual report describing the activities, initiatives, and events undertaken by the Mortara Center throughout the academic ...
The Mortara Center for International Studies
core
Observations on the phenology of the threatened Alameda whipsnake
Jeff A. Alvarez +3 more
doaj +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
The Mortara Center for International Studies Annual Report 2009-2010
Annual report describing the activities, initiatives, and events undertaken by the Mortara Center throughout the academic ...
The Mortara Center for International Studies
core
PANoptosis in the pathogenesis of myelodysplastic syndromes
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
The Mortara Center for International Studies Annual Report 2013-2014
Annual report describing the activities, initiatives, and events undertaken by the Mortara Center throughout the academic ...
The Mortara Center for International Studies
core
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Annual Report of the Department of Education for the year ending March 31st, 1967
Annual Report of the Department of Education, 1966-1967Letter of transmittal -- Personnel of department -- Part I: annual report -- Details of provincial expenditure on education -- Report of the Division of Community Leadership Development -- Report of ...
Newfoundland. Department of Education
core
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source

