Results 101 to 110 of about 2,658,760 (317)
The Mortara Center for International Studies Annual Report 2006-07
, 2007 Annual report describing the activities, initiatives, and events undertaken by the Mortara Center throughout the academic ...
The Mortara Center for International Studies
core
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
The Mortara Center for International Studies Annual Report 2009-2010
, 2010 Annual report describing the activities, initiatives, and events undertaken by the Mortara Center throughout the academic ...
The Mortara Center for International Studies
core
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
The Mortara Center for International Studies Annual Report 2010-2011
, 2011 Annual report describing the activities, initiatives, and events undertaken by the Mortara Center throughout the academic ...
The Mortara Center for International Studies
core
Observations on the phenology of the threatened Alameda whipsnake
California Fish and Wildlife Journal, 2021 Jeff A. Alvarez +3 more
doaj +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
The Mortara Center for International Studies Annual Report 2008-09
, 2009 Annual report describing the activities, initiatives, and events undertaken by the Mortara Center throughout the academic ...
The Mortara Center for International Studies
core
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source