Results 81 to 90 of about 2,658,760 (317)
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Annual Report of the Department of Education, Newfoundland, 1923-1924
, 1925 Annual Report of the Department of Education, 1923-1924Report year ends June ...
Newfoundland. Department of Education
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Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Annual Report of the Department of Education, Newfoundland, 1921-1922
, 1921 Annual Report of the Department of Education, 1921-1922Report year ends June ...
Newfoundland. Department of Education
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Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
, 2015 Submitted by Janet Brown (brown@psc.edu) on 2015-07-22T06:40:06Z No. of bitstreams: 1 XSEDE PY4 Annual Report.pdf: 18561220 bytes, checksum: e0dea487614a707623a9c2745515c5c6 (MD5)Made available in DSpace on 2015-07-22T06:40:06Z (GMT). No.
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Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
, 2017 Nutrients are a building block of life. Yet millions of people suffer from undernutrition and micronutrient malnutrition globally. The scope of impact is staggering: a lack of nourishment can lead to a lifetime of challenges, including stunted cognitive ...
International Food Policy Research Institute (IFPRI)
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Frontiers in Plant Science, 2017 Spike-related traits such as spike length (Sl), fertile spikelet number (Fsn), sterile spikelet number (Ssn), grain number per spike (Gns), and thousand-kernel weight (Tkw) are important factors influencing wheat yield.
Zhiying Deng +5 more
doaj +1 more source