Results 81 to 90 of about 3,398,936 (266)

2014 Annual report

open access: yes, 2017
Nutrients are a building block of life. Yet millions of people suffer from undernutrition and micronutrient malnutrition globally. The scope of impact is staggering: a lack of nourishment can lead to a lifetime of challenges, including stunted cognitive ...
International Food Policy Research Institute (IFPRI)
core  

Discovery of Consistent QTLs of Wheat Spike-Related Traits under Nitrogen Treatment at Different Development Stages

open access: yesFrontiers in Plant Science, 2017
Spike-related traits such as spike length (Sl), fertile spikelet number (Fsn), sterile spikelet number (Ssn), grain number per spike (Gns), and thousand-kernel weight (Tkw) are important factors influencing wheat yield.
Zhiying Deng   +5 more
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

The Mortara Center for International Studies Annual Report 2011-2012

open access: yes, 2012
Annual report describing the activities, initiatives, and events undertaken by the Mortara Center throughout the academic ...
The Mortara Center for International Studies
core  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

The Mortara Center for International Studies Annual Report 2007-08

open access: yes, 2008
Annual report describing the activities, initiatives, and events undertaken by the Mortara Center throughout the academic ...
The Mortara Center for International Studies
core  

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

The Mortara Center for International Studies Annual Report 2012-2013

open access: yes, 2013
Annual report describing the activities, initiatives, and events undertaken by the Mortara Center throughout the academic ...
The Mortara Center for International Studies
core  

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

The Mortara Center for International Studies Annual Report 2008-09

open access: yes, 2009
Annual report describing the activities, initiatives, and events undertaken by the Mortara Center throughout the academic ...
The Mortara Center for International Studies
core  

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