Results 71 to 80 of about 23,791 (265)

Direct Computation of an Annular Liquid Jet

open access: yesJournal of Algorithms & Computational Technology, 2007
An Eulerian approach with mixed-fluid treatment has been used to study the flow field of an annular liquid jet in a compressible gas medium. A mathematical formulation is developed which is capable of representing the two-phase flow system with the gas ...
Xi Jiang, George A. Siamas
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

The method of fundamental solutions for annular shaped domains

open access: yesJournal of Computational and Applied Mathematics, 2009
In order to solve the 2D Dirichlet problem for Laplace's equation the author utilizes the collocation Trefftz method. One uses the fundamental solutions as admissible functions. A group of fundamental solutions (sources) are unifomly located on an outside circle of the bounded simply-connected domain and two groups of fundamental solutions are ...
openaire   +2 more sources

Expanding Annular Domain Algorithm to Estimate Domains of Attraction for Power System Stability Analysis

open access: yesCSEE Journal of Power and Energy Systems
This paper presents an Expanding Annular Domain (EAD) algorithm combined with Sum of Squares (SOS) programming to estimate and maximize the domain of attraction (DA) of power systems.
Yuqing Lin   +3 more
doaj   +1 more source

The ubiquitin system in normal and infected germinal center B cells

open access: yesFEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis   +2 more
wiley   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

A Critical Domain for the First Normalized Nontrivial Steklov Eigenvalue Among Planar Annular Domains

open access: yes, 2023
We describe a shape derivative approach to provide a candidate for an optimal domain among non-simply connected planar domains with two boundary components. This approach is an adaptation of the work on the extremal eigenvalue problem for the Wentzell-Laplace operator developed by Dambrine, Kateb and Lamboley.
openaire   +2 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

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