Results 161 to 170 of about 1,327,897 (226)

TECTB Variants Reveal Tectorial Membrane Vulnerability in Dominant Non‐Syndromic Hearing Loss

open access: yesAdvanced Science, EarlyView.
TECTB is a non‐collagenous protein of the tectorial membrane – an extracellular matrix of the cochlea. This study identifies dominant missense variants in TECTB linked to human hereditary deafness in two unrelated families. Genetically engineered mice homozygous for one of the variants are profoundly deaf, whereas heterozygous mice have normal hearing ...
Evan B. Hale   +23 more
wiley   +1 more source

Mitochondria‐Targeted Multimodal Nanotherapeutics Suppress Oxidized mtDNA‐Driven Inflammation at the Source

open access: yesAdvanced Science, EarlyView.
Ox‐mtDNA fragments escaping from mitochondria drive robust inflammatory responses. A targeted nanoplatform simultaneously inhibits mitochondrial FEN1‐mediated mtDNA cleavage and scavenges ROS, preventing the generation of immunogenic Ox‐mtDNA fragments. The released SeNPs further promote autophagic clearance of cytosolic mtDNA. Consequently, cGAS‐STING,
Wen‐Ling Li   +7 more
wiley   +1 more source

Aggregation of adult parasitic nematodes in sex-mixed groups analysed by transient anomalous diffusion formalism. [PDF]

open access: yesJ R Soc Interface
Leben R   +8 more
europepmc   +1 more source

Deposition Rate‐Controlled Functional Evolution of p‐Type Selenium‐Alloyed Tellurium–Tellurium Oxide Films for Thin‐Film Transistors

open access: yesAdvanced Science, EarlyView.
This study investigates the effects of thermal deposition rate on next‐generation p‐type amorphous oxide semiconductor SeTe–TeOx films. Deposition rate governs the chemical states, microstructure, and electrical characteristics of the films, resulting in tunable device properties.
Seongmo Kang   +8 more
wiley   +1 more source

Anomalous Diffusion Characterization by Fourier Transform-FRAP with Patterned Illumination. [PDF]

open access: yesBiophys J, 2020
Geiger AC   +5 more
europepmc   +1 more source

Programmable Guest‐Induced 5‐Phase‐Transition Topological Reconstructions of Cobalt Formate Metal–Organic Frameworks

open access: yesAdvanced Science, EarlyView.
A reversible five‐phase topological cycle is achieved in a minimalist cobalt formate metal–organic framework. The amorphous phase functions as a programmable reactive hub, selectively reconstructing into four distinct crystalline architectures through cationic templates, humidity, or CO2.
Zhiyu Tao   +6 more
wiley   +1 more source

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