Results 41 to 50 of about 2,747 (174)

Late Cognitive or Mood Alterations With ‘Status Cribrosum’ and Diffuse White Matter Lesions: A New Cerebral Small Vessel Disease Phenotype Associated With Rare COL4A1 Variants Located Within Exon 23

open access: yesEuropean Journal of Neurology, Volume 33, Issue 7, July 2026.
We report four unrelated patients carrying rare COL4A1 glycine variants encoded by exon 23 and presenting with late‐onset cognitive and/or psychiatric symptoms. Brain MRI was characterised by a severe cerebral small vessel disease with diffuse white matter hyperintensities and prominent enlargement of basal ganglia perivascular spaces leading to a ...
Hélène Morel   +9 more
wiley   +1 more source

Association of Anxiety Awareness with Risk Factors of Cognitive Decline in MCI

open access: yesBrain Sciences, 2021
Studies demonstrate that anxiety is a risk factor for cognitive decline. However, there are also study findings regarding anxiety incidence among people with mild cognitive impairment (MCI), which mostly examined general anxiety evaluated by subjective ...
Ariela Gigi, Merav Papirovitz
doaj   +1 more source

Examining Anosognosia of Neglect [PDF]

open access: yesOTJR: Occupational Therapy Journal of Research, 2017
Unilateral neglect (neglect) and anosognosia often co-occur post stroke. It is unknown whether anosognosia of neglect varies for different types of daily activities. The objective is to examine the frequency of anosognosia of neglect for items on the Catherine Bergego Scale (CBS) and to determine the level of agreement between participant/assessor item
Emily S, Grattan   +2 more
openaire   +2 more sources

Self‐Reported Driving Problems Predict Future Traffic Crashes in Older Men: Prevalence and Determinants of Unrecognized Imminent Risk

open access: yesJournal of the American Geriatrics Society, Volume 74, Issue 7, Page 2011-2020, July 2026.
Drivers with low education and slow TMT‐B performance had a more than twofold higher crash risk than the high‐education, fast TMT‐B reference group. ABSTRACT Background Older drivers exhibit elevated crash risk per distance driven, yet accurately identifying high‐risk individuals without unjustly restricting mobility remains challenging.
Ji Won Han   +13 more
wiley   +1 more source

Improving the clinical trial landscape for patients with atypical variants of Alzheimer's disease: a call to action

open access: yesAlzheimer's &Dementia, Volume 22, Issue 6, June 2026.
Abstract Patients with atypical variants of Alzheimer's disease (AD) often present at a younger age with predominantly non‐amnestic impairments and a more aggressive disease course. Historically, individuals with atypical presentations have not been included in large‐scale clinical trials, which typically focus on late‐onset, sporadic amnestic ...
Nick Corriveau‐Lecavalier   +36 more
wiley   +1 more source

Questionnaire «Opioid anosognosia» is a new tool for assessment anosognosia in opioid-dependent patients

open access: yesОбозрение психиатрии и медицинской психологии имени В.М. Бехтерева
The absence of reliable, valid, and widely accepted measurement tools hinders the study of opioid anosognosia. The aim of this study: to develop, validate, and standardize a self-report questionnaire for the rapid and comprehensive assessment of opioid ...
R. D. Ilyuk   +7 more
doaj   +1 more source

Awareness of Cognitive Decline in Patients With Alzheimer's Disease: A Systematic Review and Meta-Analysis

open access: yesFrontiers in Aging Neuroscience, 2021
Background: Identifying a poor degree of awareness of cognitive decline (ACD) could represent an early indicator of Alzheimer's disease (AD).Objectives: (1) to understand whether there is evidence of poor ACD in the pre-dementia stages of AD; (2) to ...
Federica Cacciamani   +29 more
doaj   +1 more source

Stress, stress systems, and Alzheimer's disease

open access: yesAlzheimer's &Dementia, Volume 22, Issue 6, June 2026.
Abstract Stress is increasingly recognized as an important, modifiable factor for Alzheimer's disease (AD), yet its roles in initiation, progression, and outcomes remain incompletely elucidated. Epidemiologic studies link chronic stress, early‐life adversity, and trauma to increased AD risk, while experimental models have uncovered mechanisms by which ...
Stephanie G. Eberly   +5 more
wiley   +1 more source

Brain regions associated with anosognosia for memory disturbance in Alzheimer’s disease: a magnetic resonance imaging study

open access: yesNeuropsychiatric Disease and Treatment, 2017
Hiroshi Fujimoto,1 Teruyuki Matsuoka,1 Yuka Kato,1 Keisuke Shibata,1 Kaeko Nakamura,1 Kei Yamada,2 Jin Narumoto1 1Department of Psychiatry, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan; 2Department of ...
Fujimoto H   +6 more
doaj  

Falls and Fear of Falling in Minor Stroke Patients With Vestibular Symptoms: A Longitudinal Observational Study

open access: yesBrain and Behavior, Volume 16, Issue 6, June 2026.
This prospective study reveals that persistent vestibular symptoms, cerebral small vessel disease, and anxiety/depression predict long‐term fall risk in minor stroke patients. Early identification and intervention within the first 3 months poststroke may help mitigate balance impairment and improve outcomes.
Yao Zhong   +5 more
wiley   +1 more source

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