Results 51 to 60 of about 2,747 (174)

Anosognosia is associated with increased prevalence and faster development of neuropsychiatric symptoms in mild cognitive impairment

Frontiers in Aging Neuroscience
IntroductionBoth the loss of awareness for cognitive decline (a. k.a anosognosia) and neuropsychiatric symptoms (NPS) are common in patients with Alzheimer's disease (AD) dementia, even in prodromal stages, and may exacerbate functional impairment and ...
Sharon Wang, Kayden Mimmack, Federica Cacciamani, Federica Cacciamani, Federica Cacciamani, Federica Cacciamani, Michael Elnemais Fawzy, Michael Elnemais Fawzy, Catherine Munro, Catherine Munro, Catherine Munro, Jennifer Gatchel, Jennifer Gatchel, Jennifer Gatchel, Gad A. Marshall, Gad A. Marshall, Gad A. Marshall, Geoffroy Gagliardi, Geoffroy Gagliardi, Geoffroy Gagliardi, Patrizia Vannini, Patrizia Vannini, Patrizia Vannini   +22 more
doaj   +1 more source

Exploring stigma in Huntington's disease: A scoping review of methods and conceptualizations for understanding experiences of gene expansion carriers and at‐risk individuals

Journal of Genetic Counseling, Volume 35, Issue 3, June 2026.
Abstract Many individuals affected by the hereditary neurological condition Huntington's disease (HD) have reported experiences of stigmatization, yet the extant literature is currently theoretically and methodologically underdeveloped. Therefore, this scoping review aimed to examine the methodological approaches and theoretical conceptualizations of ...
Tierney Tindall, Jane Simpson, Maria Dale, Sarah Gunn   +3 more
wiley   +1 more source

Capturing Behavioral Symptoms in Huntington's Disease Using the Huntington's Disease‐Behavioral Questionnaire

Movement Disorders Clinical Practice, Volume 13, Issue 6, Page 1513-1517, June 2026.
Abstract Background The Huntington's Disease Behavioral Questionnaire (HD‐BQ) captures behavioral symptoms arising from cognitive, psychiatric, and functional domains. Recognizing the high prevalence of anosognosia in HD, the HD‐BQ incorporates patient‐ and companion‐reported versions.
Siena Rigatuso, Krisha Bagga, Shelby Hughes, Japleen Kaur, Paul E. Gilbert, Jody Corey‐Bloom   +5 more
wiley   +1 more source

Writing Errors and Anosognosia in Amyotrophic Lateral Sclerosis with Dementia

Behavioural Neurology, 2008
Amyotrophic lateral sclerosis (ALS) with dementia (ALS-D) is known to exhibit characteristics of frontotemporal dementia. However, in clinical situations, it is often difficult to evaluate their cognitive functions because of impaired voluntary speech ...
Hiroo Ichikawa, Shinichi Koyama, Hideki Ohno, Kenji Ishihara, Kiyomi Nagumo, Mitsuru Kawamura   +5 more
doaj   +1 more source

The Self-Awareness Multilevel Assessment Scale, a New Tool for the Assessment of Self-Awareness After Severe Acquired Brain Injury: Preliminary Findings

Frontiers in Psychology, 2020
Self-awareness (SA) is frequently impaired after severe acquired brain injury (sABI) and may lead to reduced subject’s compliance to treatment, worse functional outcome, and high caregiver distress.
Umberto Bivona, Paola Ciurli, Giulia Ferri, Tiziana Fontanelli, Susanna Lucatello, Teresa Donvito, Dolores Villalobos, Dolores Villalobos, Laura Cellupica, Fabiana Mungiello, Paola Lo Sterzo, Amalia Ferraro, Eleonora Giandotti, Giorgio Lombardi, Eva Azicnuda, Carlo Caltagirone, Carlo Caltagirone, Rita Formisano, Alberto Costa, Alberto Costa   +19 more
doaj   +1 more source

STUB1 (SCA48)/TBP (SCA17): A Frequent Association Still Not Fully Explained and a Lower Threshold for Intermediate Expanded TBP Alleles

Movement Disorders, Volume 41, Issue 7, Page 1661-1665, July 2026.
Cecilia Marelli, Quentin Charret, Cyril Goizet, Julien Thevenon, Virginie Bernard, Fabienne Ory Magne, Manon Degoutin, Patricia Fergelot, Mathilde Renaud, Michel Koenig, Francis Ramond   +10 more
wiley   +1 more source

Psychological care for Huntington's disease: A qualitative study exploring interventions in the Netherlands

Psychology and Psychotherapy: Theory, Research and Practice, Volume 99, Issue 2, Page 443-462, June 2026.
Abstract Objectives Huntington's disease (HD) is a hereditary neurodegenerative disorder characterized by a range of motor, cognitive, and psychiatric symptoms. Psychological symptoms can arise from being at risk for the disease and from its manifestation, necessitating psychological interventions to address the evolving burden, even before onset. This
Kasper F. Van der Zwaan, Laura C. M. Kuijper, Pearl J. C. van Lonkhuizen, Raymund A. C. Roos, Susanne T. de Bot   +4 more
wiley   +1 more source

Activities of daily living and their neural correlates across the Alzheimer's disease continuum: Evidence from a Latin American cohort

Alzheimer's &Dementia, Volume 22, Issue 5, May 2026.
Abstract INTRODUCTION Functional decline in activities of daily living (ADL)—advanced (AADL), instrumental (IADL), and basic (BADL)—is a hallmark of Alzheimer's disease (AD). However, integrated clinical–neuroanatomical evidence on progression across the AD continuum remains limited, particularly in Latin American populations.
Fernando Henríquez, Patricio Riquelme, Gonzalo Forno, Joaquín Migeot, Rodrigo Henríquez, Patricia Lillo, Daniela Thumala‐Dockendorff, Cecilia Okuma, Cecilia González Campo, Michael Hornberger, Francisco Aboitiz, Andrea Slachevsky   +11 more
wiley   +1 more source

Mandarin speech‐based early detection of SCD: a feature‐fusion residual network method

Alzheimer's &Dementia, Volume 22, Issue 5, May 2026.
Abstract INTRODUCTION Alzheimer's disease (AD) poses a global health challenge. Early intervention during the stage of subjective cognitive decline (SCD) – a potential window for delaying disease progression – is crucial. This study aims to assess an exploratory speech‐based model for rapid SCD screening.
Zhou Liu, Chao Che, Guimei He, Hanyu Wu, Lei Cai, Lili Cui, Lizhong Liang   +6 more
wiley   +1 more source

Underprescription of Clozapine: A Narrative Review Regarding ‘Clozaphobia’

Human Psychopharmacology: Clinical and Experimental, Volume 41, Issue 3, May 2026.
ABSTRACT This review aims to examine the appropriateness of the term ‘clozaphobia’ to characterise the obstacles contributing to the underprescription of clozapine (CLZ). English‐language, peer‐reviewed studies addressing clinicians', patients' and/or carers' attitudes toward CLZ were considered eligible for full‐text review.
Rafael Brito Castro, Joaquim J. Ferreira, João Gama‐Marques   +2 more
wiley   +1 more source