Results 71 to 80 of about 3,679,149 (318)

Barriers and facilitators to HIV index contact testing in facility and community settings

open access: yesSouthern African Journal of HIV Medicine
Background: The WHO emphasises contact investigation of people with HIV for case finding. However, satisfactory implementation of index contact testing remains challenging in Johannesburg.
Nyeleti Pretty Chauke   +4 more
doaj   +1 more source

Examining research productivity of Chinese TEFL academics across departments and institutes [PDF]

open access: yes, 2010
This study aims to benchmark Chinese TEFL academics’ research productivities, as a way to identify and, subsequently, address research productivity issues.
Bai, Li, Hudson, Peter
core   +2 more sources

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Differentiated antiretroviral distribution: Implementation in five South African districts

open access: yesAfrican Journal of Primary Health Care & Family Medicine
Background: The National Department of Health introduced Differentiated Service Delivery (DSD) models to improve retention in care and decongest healthcare facilities.
Justin Engelbrecht   +3 more
doaj   +1 more source

Optimal randomized multilevel algorithms for infinite-dimensional integration on function spaces with ANOVA-type decomposition

open access: yes, 2012
In this paper, we consider the infinite-dimensional integration problem on weighted reproducing kernel Hilbert spaces with norms induced by an underlying function space decomposition of ANOVA-type.
Baldeaux J.   +7 more
core   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Baseline CD4 and mortality trends in the South African human immunodeficiency virus programme: Analysis of routine data

open access: yesSouthern African Journal of HIV Medicine, 2019
Background: Despite widespread availability of antiretroviral therapy (ART) in South Africa, there remains a considerable burden of human immunodeficiency virus (HIV)-related morbidity and mortality.
Rivka R. Lilian   +5 more
doaj   +1 more source

Pseudo Bayesian Estimation of One-way ANOVA Model in Complex Surveys

open access: yes, 2020
We devise survey-weighted pseudo posterior distribution estimators under 2-stage informative sampling of both primary clusters and secondary nested units for a one-way ANOVA population generating model as a simple canonical case where population model ...
Savitsky, Terrance D.   +1 more
core  

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

Pengaruh penambahan tepung agar terhadap komposisi kimia serbuk agar dari kolang-kaling

open access: yesJLI: Jurnal Litbang Industri, 2019
Pemanfaatan kolang-kaling sebagai produk pangan dalam bentuk serbuk memberikan nilai tambah bagi buah tersebut. Buah ini memiliki kandungan mineral yang cukup banyak, seperti: potassium, besi dan kalsium yang bermanfaat dan dapat memperlancar proses ...
Inda Three Anova, K Kamsina
doaj   +1 more source

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