Results 81 to 90 of about 3,271,002 (290)

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

The role of health and advocacy organisations in assisting female sex workers to gain access to health care in South Africa

BMC Health Services Research, 2019
Background Globally, female sex workers (FSWs) are considered a key population group due to the high HIV prevalence. Studies show that there are various factors in some contexts that render FSWs marginalised, which limits their access to sexual ...
Nosipho Faith Makhakhe, Anna Meyer-Weitz, Helen Struthers, James McIntyre   +3 more
doaj   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

The heterogeneity among people re‐engaging in antiretroviral therapy highlights the need for a differentiated approach: results from a cross‐sectional study in Johannesburg, South Africa

Journal of the International AIDS Society
Introduction Disengagement and re‐engagement with antiretroviral therapy (ART) are common in South Africa, but routine monitoring is insufficient to inform policy development. To address this gap, Anova implemented the 2020 National Adherence Guidelines’
Chipo Mutyambizi, Kate Rees, Anna Grimsrud, Rendani Ndou, Lynne S. Wilkinson   +4 more
doaj   +1 more source

La participación voluntaria en situaciones de emergencia

Papers, 2010
El desastre ecológico sufrido en las costas gallegas después del hundimiento del Prestige generó un cambio de actitud hacia la participación activa en defensa del medio ambiente.
Pilar García Soidán, Herminia Dios Poceiro, Rebeca Villaverde López, Óscar Rubiños López   +3 more
doaj   +1 more source

Using authentic 3D product visualisation for an electrical online retailer [PDF]

, 2009
This study investigates the effects of authentic three dimensional (3D) product visualisation versus 3D telepresence on consumers’ virtual experience.
Algharabat, R, Dennis, C
core  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

PERBEDAAN PRESTASI BELAJAR SISWA ANTARA KELAS UMUM DAN KELAS OLAHRAGA BERDASARKAN TINGKAT PENDIDIKAN ORANGTUA PADA KELAS VII SMP N 4 PURBALINGGA [PDF]

, 2012
Penelitian ini bertujuan untuk mengetahui apakah ada perbedaan prestasi belajar siswa antara kelas umum dengan kelas olahraga kelas VII SMP N 4 Purbalingga, kelas manakah yang lebih baik dan dari pendidikan orangtua tingkat apa.
AUDY AKID, HIBATULLOH
core  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Disclosure of human immunodeficiency virus status to children in South Africa: A comprehensive analysis

Southern African Journal of HIV Medicine, 2019
Background: The extent of disclosure of HIV status to children and adolescents and the context facilitating their disclosure process have received little attention.
Sabine L. van Elsland, Remco P.H. Peters, Cornelis Grobbelaar, Patiswa Ketelo, Maarten O. Kok, Mark F. Cotton, A. Marceline van Furth   +6 more
doaj   +1 more source