Results 71 to 80 of about 3,271,002 (290)

Pseudo Bayesian Estimation of One-way ANOVA Model in Complex Surveys

, 2020
We devise survey-weighted pseudo posterior distribution estimators under 2-stage informative sampling of both primary clusters and secondary nested units for a one-way ANOVA population generating model as a simple canonical case where population model ...
Savitsky, Terrance D., Williams, Matthew R.   +1 more
core  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

ANOVA în cercetrările de marketing [PDF]

In order to make an analysis of the variation regarding ANOVA, we considered the commercial society S.C. RUCOM S.A. from Craiova, Dolj, 107 Caracal Street, dealer in the sale of cars mark Opel, even from 2002. Starting with 2004, S.C. RUCOM S.A.
Tomescu Dumitrescu, C.
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Public Men’s Clinic: Men’s experiences of healthcare professionals and environment

African Journal of Primary Health Care & Family Medicine
Background: Men often face social barriers linked to norms and systemic issues when engaging with public healthcare services. South Africa’s first Public Men’s Clinic (PMC) was established in 2020, and now, 20 more clinics operate across the country ...
Lawrence L. Mamabolo, Isaac Sibiya, Fezile Buthelezi   +2 more
doaj   +1 more source

Multi-institutional Registry for Prostate Cancer Radiosurgery: An Observational Clinical Trial

Frontiers in Oncology, 2015
Title: Multi-institutional Registry for Prostate Cancer Radiosurgery: An Observational Clinical TrialAuthors: Debra Freeman, MD*; Gregg Dickerson, MD; Mark Perman, MDObjective: To report on the design, methodology and early outcome results of a multi ...
Debra eFreeman, Gregg eDickerson, Mark ePerman   +2 more
doaj   +1 more source

Implementation of a PMTCT programme in a high HIV prevalence setting in Johannesburg, South Africa: 2002–2015

Southern African Journal of HIV Medicine, 2020
Background: Great strides have been made in decreasing paediatric human immunodeficiency virus (HIV) infections, especially in sub-Saharan Africa. In South Africa, new paediatric HIV infections decreased by 84% between 2009 and 2015.
Coceka Mnyani, Carol L. Tait, Remco P.H. Peters, Helen Struthers, Avy Violari, Glenda Gray, Eckhart J. Buchmann, Matthew F. Chersich, James A. McIntyre   +8 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Providing HIV care to men who have sex with men in South African state sector clinics

Southern African Journal of HIV Medicine, 2014
-
Kevin Brian Rebe, James McIntyre
doaj   +1 more source