Results 61 to 70 of about 1,934,581 (253)
Analisi della varianza (ANOVA): One-Way ANOVA, One-Way ANOVA per campioni appaiati, Two-Way ANOVA.
Plazzi, Federico
core
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
A robust procedure for comparing multiple means under heteroscedasticity in unbalanced designs. [PDF]
Investigating differences between means of more than two groups or experimental conditions is a routine research question addressed in biology. In order to assess differences statistically, multiple comparison procedures are applied.
Esther Herberich +8 more
core +1 more source
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
6. Übung (27.06.2018): ANOVA [PDF]
Seminarinhalte: Grundbegriffe ANOVA; Funktionsprinzip ANOVA ( idee des t-Tests, Idee der ANalysis Of VAriance); Einfaktorielle ANOVA; Einfaktorielle ANOVA: R; Varianten der ANOVA (zweifaktorielle ...
Toussaint, Julie, Multimediazentrum
core
El model ANOVA unifactorial [PDF]
The one-factor ANOVA modelEl modelo ANOVA unifactorialEl model ANOVA unifactorial7936.mp4 7936 ...
core
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source

