Diapause and Anoxia-Induced Quiescence Are Unique States in Embryos of the Annual Killifish, Austrofundulus limnaeus [PDF]
Diapause is a state of developmental and metabolic dormancy that precedes exposure to environmental stresses. Yet, diapausing embryos are typically stress-tolerant.
Patrick R. Clouser +3 more
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Spontaneous running wheel exercise during pregnancy prevents later neonatal-anoxia-induced somatic and neurodevelopmental alterations [PDF]
Introduction: About 15–20 % of babies that suffer perinatal asphyxia die and around 25 % of the survivors exhibit permanent neural outcomes. Minimization of this global health problem has been warranted.
Vitor Yonamine Lee +6 more
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Surviving without oxygen involves major tissue specific changes in the proteome of crucian carp (Carassius carassius) [PDF]
The crucian carp (Carassius carassius) can survive complete oxygen depletion (anoxia) for several months at low temperatures, making it an excellent model for studying molecular adaptations to anoxia.
Anette Johansen +3 more
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The role of MEF2 transcription factors in dehydration and anoxia survival in Rana sylvatica skeletal muscle [PDF]
The wood frog (Rana sylvatica) can endure freezing of up to 65% of total body water during winter. When frozen, wood frogs enter a dormant state characterized by a cessation of vital functions (i.e., no heartbeat, blood circulation, breathing, brain ...
Myriam P. Hoyeck +2 more
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The anoxia-tolerant crucian carp (Carassius carassius) has been studied in detail for numerous years, with particular focus on unravelling the underlying physiological mechanisms of anoxia tolerance.
Helge-Andre Dahl +3 more
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Anoxia/reoxygenation injury in hepatocytes is not prevented by calcium channel blockers [PDF]
Azzarone, A +7 more
core +2 more sources
Avoidance of apoptosis in embryonic cells of the annual killifish Austrofundulus limnaeus exposed to anoxia. [PDF]
Embryos of the annual killifish Austrofunduluslimnaeus have unequalled ability among vertebrates to survive long-term anoxia. Surprisingly, these embryos can survive for months in anoxia despite a large-scale decrease in ATP levels during the initial ...
Camie L Meller, Jason E Podrabsky
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Environmental and genetic preconditioning for long-term anoxia responses requires AMPK in Caenorhabditis elegans. [PDF]
Preconditioning environments or therapeutics, to suppress the cellular damage associated with severe oxygen deprivation, is of interest to our understanding of diseases associated with oxygen deprivation. Wildtype C.
Bobby L LaRue, Pamela A Padilla
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Multiple lines of evidence suggest that an inability of the ventricle to contract in coordination with the pacemaker during anoxia exposure may suppress cardiac pumping rate in anoxia-tolerant turtles. To determine under what extracellular conditions the
Molly Garner, Jonathan A.W. Stecyk
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Characterization of pyruvate kinase from the anoxia tolerant turtle, Trachemys scripta elegans: a potential role for enzyme methylation during metabolic rate depression [PDF]
Background Pyruvate kinase (PK) is responsible for the final reaction in glycolysis. As PK is a glycolytic control point, the analysis of PK posttranslational modifications (PTM) and kinetic changes reveals a key piece of the reorganization of energy ...
Amanda M.S. Mattice +3 more
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