Results 141 to 150 of about 85,813 (299)

sj-docx-1-anp-10.1177_00048674241235849 – Supplemental material for Examining the relationships between cognition and auditory hallucinations: A systematic review

Supplemental material, sj-docx-1-anp-10.1177_00048674241235849 for Examining the relationships between cognition and auditory hallucinations: A systematic review by Adrienne Bell, Wei Lin Toh, Paul Allen, Matteo Cella, Renaud Jardri, Frank Larøi, Peter ...
Peter Moseley (547302), Matteo Cella (4968856), Frank Larøi (8489385), Adrienne Bell (18149136), Renaud Jardri (310610), Paul Allen (10927290), Wei Lin Toh (10209906), Susan L Rossell (5197346)   +7 more
core   +1 more source

An intracellular recombinant single‐chain variable antibody fragment as a new class of phosphodiesterase type 5 inhibitors

British Journal of Pharmacology, EarlyView.
Background and Purpose Cyclic guanosine monophosphate (cGMP) is a ubiquitous second messenger involved in human (patho‐)physiology. Phosphodiesterase 5 (PDE5) is a major cGMP hydrolyzing enzyme in many cell types including vascular smooth muscle cells (VSMCs). Several highly selective PDE5 inhibitors are in clinical use. However, there are currently no
Kürsat Kirkgöz, Sophie Sprenger, Olga Schweigert, Sanika Mohagaonkar, Matti Walsdorff, Tanja Zeller, Filip Berisha, Viacheslav O. Nikolaev, Sergei D. Rybalkin   +8 more
wiley   +1 more source

Cancer pain: current practice and emerging targets

British Journal of Pharmacology, EarlyView.
Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye, Marcin Chwistek, Zhiting Gong, Vanessa Uzonwanne, Xiaojie Shi, Arpad Szallasi   +5 more
wiley   +1 more source

Atrial natriuretic peptide counteracts aldosterone secretion by preventing acute angiotensin II‐induced cAMP signalling

British Journal of Pharmacology, EarlyView.
Background and Purpose Aldosterone plays a key role in blood pressure and volume regulation. Enhanced aldosterone secretion contributes to cardiovascular and renal diseases. Therefore, inhibitors of aldosterone receptors and synthase are essential drugs for the treatment of hypertension and heart failure.
Sanika Mohagaonkar, Egor B. Skryabin, Bettina M. Buchholz, Michaela Kuhn, Celso E. Gomez‐Sanchez, Stepan Gambaryan, Viacheslav O. Nikolaev   +6 more
wiley   +1 more source

Population interest in and adequacy of the information on the safety of antineoplastic agents in the Spanish edition of Wikipedia.

PLoS ONE
ObjectiveTo analyse the trend in use of the main antineoplastic agents (ANP) in Spain, to determine the association of this trend with the number of visits to the related pages in the Spanish edition of Wikipedia and to verify the existence of ...
Seira Climent-Ballester, Pedro García-Salom, Javier Sanz-Valero   +2 more
doaj   +1 more source

sGC stimulator BAY 41‐8543 improves survival and ventricular function in a rat model of doxorubicin‐induced cardiomyopathy with nephrotic syndrome

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Anthracyclines such as doxorubicin (DOXO) remain a cornerstone of cancer therapy but are associated with a high risk of cardiotoxicity and subsequent heart failure (HF). Impairment of NO/soluble guanylyl cyclase (sGC)/cGMP pathway has been reported in anthracycline‐induced cardiomyopathy.
Olga Gawrys, Petra Škaroupková, Soňa Kikerlová, Zdeňka Vaňourková, Martina Hüttl, Olga Lenčová, Kasin Yadunandam Anandam, Svenja Stomberg, Sönke Behrends, Barbara Szeiffová Bačová, Matúš Sykora, Lisa Dietz, Peter Sandner, Luděk Červenka, Martin Štěrba   +14 more
wiley   +1 more source

Bridging the implementation gap in MCABC inventory management: from a taxonomy to practical archetypes

International Transactions in Operational Research, EarlyView.
Abstract Despite increasing demands for resilient and sustainable supply chains, inventory management often relies on outdated single‐criterion analyses. While multi‐criteria ABC (MCABC) analyses provide a theoretically mature assessment of resilience‐sustainability‐benefit trade‐offs in inventory, their adoption remains limited due to fragmented ...
Lukas Grützner, Michael H. Breitner
wiley   +1 more source

Safety Risk assessment in Motor vehicle industries by using William fine and ANP-DEMATEL

Salāmat-i kār-i Īrān, 2017
Background and aims: Risk assessment is one of the most important issues in making safety industrial environments. Motor vehicle industries  are one  of the most unsafe industries that  have many annual accident.
Zahra Navaie aznave, Manouchehr Omidvari
doaj  

A spectral analysis extension to DEMATEL for strategic leverage points identification

International Transactions in Operational Research, EarlyView.
Abstract Efforts to intervene in complex systems often emphasize influential factors, yet system behavior is equally shaped by the relationships among them. Methods such as Decision‐Making Trial and Evaluation Laboratory (DEMATEL) map causal structures but remain descriptive and do not identify which relationships provide the greatest leverage for ...
Pavlos Delias, Kerasia Kalkitsa
wiley   +1 more source

Challenges to artificial intelligence‐enabled digital technology adoption in farms: a multi‐method approach

International Transactions in Operational Research, EarlyView.
Abstract Artificial intelligence (AI)‐enabled digital technologies have the potential to transform agriculture by supporting decision‐making and automating operations. However, their limited adoptions and scholars’ atheoretical explorations constrain our understanding.
Guoqing Zhao, Shaofeng Liu, Xiaoning Chen, Huilan Chen, Xinyi Li, Guoste Pivoraite   +5 more
wiley   +1 more source