Results 151 to 160 of about 28,060 (254)

The Role of Inflammation and Immunity in Cardiovascular Disease: Molecular Mechanisms and Therapeutic Targets

MedComm, Volume 7, Issue 8, August 2026.
Inflammation in cardiovascular disease is a dynamic and context‐dependent network rather than a secondary response to injury. Mitochondrial danger signaling links metabolic stress to immune activation through TLR priming, NLRP3 inflammasome amplification, cGAS–STING signaling, and immunometabolic gating, providing a basis for more precise therapeutic ...
Jiaxiang Rong, Zhen Wang, Xiaoxiao Lin, Ziwen Lei, Qianqian Huang, Hang Liu, Fei Luan, Junbo Zou, Yajun Shi   +8 more
wiley   +1 more source

Age-friendly design of health detection integrated machine: A user requirement-driven approach. [PDF]

Sci Rep
Shi Y, Xie Y.
europepmc   +1 more source

Numerical Modeling of Geological Fault Reactivation Using Sequential Coupling Strategies

International Journal for Numerical and Analytical Methods in Geomechanics, Volume 50, Issue 11, Page 4339-4359, 10 August 2026.
ABSTRACT The interaction between fluid flow and mechanical deformation in fault zones can lead to processes of fault reactivation, triggering potential geomechanical problems such as seismicity, well collapse, fluid migration to shallower layers, and aggravated surface subsidence.
Julio Rueda, Cristian Mejia, Roberto Quevedo, Deane Roehl   +3 more
wiley   +1 more source

Pathogenic KIF1A R350 mutations disrupt a conserved and conformation-dependent kinesin-tubulin salt bridge. [PDF]

Nat Commun
Shatarupa A, Rao L, Asenjo AB, Gennerich A, Sosa H.   +4 more
europepmc   +1 more source

Assessing the Effects of Biodiesel Production on Sustainability: A Bayesian Two‐Stage Data Envelopment Analysis Approach

Sustainable Development, Volume 34, Issue 4, Page 5648-5668, August 2026.
ABSTRACT Sustainable development transforms production systems, requiring integrated environmental, social, and economic strategies. Energy systems are key agro‐industrial supply chains in developing countries. Brazil's soybean supply chain impacts Gross Domestic Product, mainly through exports.
Aline Veronese da Silva, Camila Veneo Campos Fonseca, Pedro Gerber Machado, Marcelo Azevedo Costa   +3 more
wiley   +1 more source

Atrial TRPM2 Channel-Mediated Ca²⁺ Influx Regulates ANP Secretion and Protects Against Isoproterenol-Induced Cardiac Hypertrophy and Fibrosis. [PDF]

Cells
Numata T, Tagashira H, Sato-Numata K, Hermosura MC, Abe F, Sakai A, Yamamoto S, Watanabe H.   +7 more
europepmc   +1 more source

Targeting of Pentraxin 3 Alleviated Cardiac Hypertrophy in Mice Induced by Angiotensin II

Clinical and Experimental Pharmacology and Physiology, Volume 53, Issue 8, August 2026.
ABSTRACT Pentraxin 3 (PTX3) responds rapidly to inflammatory signals. This study investigated the functional involvement of PTX3 in angiotensin II (Ang II)‐mediated cardiac hypertrophy pathogenesis, with particular focus on its potential regulation through inflammatory pathways and oxidative stress mechanisms.
Qiming Tan, Xiaoxuan Gong, Tian Wu, Chen Li, Kun Liu, Daorong Hou   +5 more
wiley   +1 more source

Bifidobacterium adolescentis attenuates cardiac remodeling in HFD/STZ-induced obesity-associated diabetic cardiomyopathy. [PDF]

Sci Rep
Bolandparvaz A, Amoozegar H, Pouyan P, Rahmani A, Naqiloo F, Ali Zadeh S, Alizad Z, Abdoli Rezaei S, Mehboodi M, Rahimi A, Ghafari M, Ghalehnoo SR.   +11 more
europepmc   +1 more source

A Service Evaluation of a Specialist Multi‐Disciplinary Weight Management Service Based in Primary Care Including Long‐Term Follow‐Up Data

Clinical Obesity, Volume 16, Issue 4, August 2026.
ABSTRACT This service evaluation of a primary care‐based specialist weight management service reports data from 1094 patients over 5 years (2014–2019), including weight data at 1‐year post‐discharge. The results show clinically and statistically significant improvements in weight, diet, physical activity, quality of life, blood pressure and blood ...
Helen M. Parretti, Carly A. Hughes, Sally Erskine, Nicholas Steel, Amy Jennings   +4 more
wiley   +1 more source

Differentiation of ecological niche patterns between sympatric lemurs in northwestern Madagascar: Implications for their conservation. [PDF]

PLoS One
Mercado Malabet F, Randimbiarison FT, Razafimampiandra JC, Andriatsitohaina B, Chell C, Razafitsalama M, Steffens TS, Lehman SM.   +7 more
europepmc   +1 more source