Results 31 to 40 of about 136,013 (165)

Impaired Intracellular Transport and Cell Surface Expression of Nonpolymorphic HLA-E [PDF]

, 1992
The assembly of the classical, polymorphic major histocompatibility complex class I molecules in the endoplasmic reticulum requires the presence of peptide ligands and ~2-microglobulin (~2m). Formation of this trimolecular complex is a prerequisite for e~
Kellermann, Josef, Johnson, Judith P., Matthias Ulbrecht, Ulbrecht, Matthias, Josef Kellermann, Judith P. Johnson, Weiss, Elisabeth H., Elisabeth H. Weiss   +7 more
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O sistema HLA

Semina: Ciências Agrárias, 1981
  Revisão bibliográfica, apresentando algumas características do complexo principal de histocompatibilidade humana (HLA). Discussão dos mecanismos mais prováveis para explicar as associações encontradas entre os antígenos do sistema HLA e algumas ...
Aldo Waldrigues
doaj   +1 more source

Replication of the association of HLA-B7 with Alzheimer's disease: a role for homozygosity? [PDF]

, 2006
Background: There are reasons to expect an association with Alzheimer's disease (AD) within the HLA region. The HLA-B & C genes have, however, been relatively understudied.
Smith, AD, Horton Roger, Barnardo Martin CNM, Stephan Beck, Warden Donald R, Warden, DR, Martin CNM Barnardo, Barnetson, L, Smith A David, Andrew Sutherland, Lehmann, DJ, Beck Stephan, Barnardo, MC, Isabel Quiroga, Fuggle Susan, Barnetson Lin, Barnardo, MCNM, Quiroga Isabel, Lehmann Donald J, Roger Horton, Beck, S, Susan Fuggle, Donald R Warden, Fuggle, S, Sutherland Andrew, Sutherland, A, Donald J Lehmann, Lin Barnetson, A David Smith, Quiroga, I, Horton, R   +30 more
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CÉLULAS CAR-T EXPRESSANDO UMA NOVA CONSTRUÇÃO CONTRA O ANTÍGENO INTRACELULAR MAGE-A4 INDUZEM REGRESSÃO TUMORAL COMPLETA EM MODELO DE MIELOMA MÚLTIPLO

Hematology, Transfusion and Cell Therapy, 2023
Introdução/Objetivo: Os receptores de antígenos quiméricos (CARs) convencionais reconhecem apenas antígenos de superfície celular em sua conformação nativa.
RM Silveira, IP Furtado, DMC Fantacini, R Rossetti, AUQ Ferreira, L Tsyrenov, H Shiku, DT Covas, LEB Souza   +8 more
doaj   +1 more source

High-throughput high-resolution class I HLA genotyping in East Africa. [PDF]

, 2010
HLA, the most genetically diverse loci in the human genome, play a crucial role in host-pathogen interaction by mediating innate and adaptive cellular immune responses. A vast number of infectious diseases affect East Africa, including HIV/AIDS, malaria,
Leonard Maboko, Eller, Michael, Jerome Kim, Rebecca N Koehler, Francine E McCutchan, Michael Eller, Christian T Bautista, Hoelscher Michael, Eller, Leigh Anne, Jeffrey R Currier, Currier Jeffrey R., Nelson L Michael, Michael, Nelson L., Kijak, Gustavo H, Maboko Leonard, Michael, Nelson L, McCutchan, Francine E., Michael Nelson L., Maboko, Leonard, Walsh, Anne M, Wabwire-Mangen Fred, Fred Wabwire-Mangen, Wabwire-Mangen, Fred, Currier, Jeffrey R, Eller Michael, McCutchan, Francine E, Eric E Sanders-Buell, Sanders-Buell, Eric E., Robb, Merlin L, Robb Merlin L., Kijak Gustavo H., Leigh Anne Eller, Kim Jerome, Robb, Merlin L., Bautista Christian T., Anne M Walsh, Hoelscher, Michael, Kijak, Gustavo H., Bautista, Christian T, Michael Hoelscher, McCutchan Francine E., Kim, Jerome, Eller Leigh Anne, Koehler, Rebecca N, Merlin L Robb, Bautista, Christian T., Koehler, Rebecca N., Koehler Rebecca N., Sanders-Buell, Eric E, Sanders-Buell Eric E., Walsh, Anne M., Currier, Jeffrey R., Gustavo H Kijak, Walsh Anne M.   +53 more
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Allogeneic Hematopoietic Stem Cell Transplant recipients in Spain: Human Leucocyte Antigen characteristics and diversity by high-resolution analysis

There are many studies on the polymorphism of the HLA system in healthy donor populations, such as registries of unrelated bone marrow donors. Investigations on the characterization of the HLA complex in hematopoietic stem cell transplant (HSCT) patients,
Solano Vercet, Carlos, Planelles Silvestre, Dolores, Piñana, José Luis, Guerreiro, Manuel   +3 more
core   +1 more source

Contributions of vitamin D response elements and HLA promoters to multiple sclerosis risk [PDF]

, 2012
Objective: The identification of a vitamin D-responsive (VDRE) motif within the HLA-DRB1*15:01 promoter region provides an attractive explanation for the combined effects of HLA-DR inheritance and vitamin D exposure on multiple sclerosis (MS) risk.
Qiu, W., Nolan, D., Kermode, A., Tschochner, M., Mastaglia, F., Christiansen, F.T., Witt, C., Castley, A., James, I., Sayer, D., Carroll, W.   +10 more
core  

The HLA-DRA*0102 allele: correct nucleotide sequence and associated HLA haplotypes

, 2002
Here we correct the nucleotide sequence of a single known variant of the HLA-DRA gene. We show that the coding regions of the HLA-DRA*0101 and HLA-DRA*0102 alleles do not differ at two codons as reported previously, but only in codon 217.
Marsh, SGE, Marsh, S. G., Kralovicova, J, Hammarstrom, L, Kralovicova, J., Hammarstrom, L., Vorechovsky, I, Waller, M. J., Vorechovsky, I., Waller, MJ   +9 more
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AVALIAÇÃO DO GRAU DE SENSIBILIZAÇÃO A ANTICORPOS ANTI-HLA EM PACIENTES PRÉ-TRANSPLANTE DE CÉLULAS-TRONCO HEMATOPOIÉTICAS (TCTH) CADASTRADOS NO LABORATÓRIO DE HLA DA FUNDAÇÃO HEMOCENTRO DE RIBEIRÃO PRETO

Hematology, Transfusion and Cell Therapy
Objetivos: Avaliar o grau de sensibilização a anticorpos anti-HLA dos pacientes candidatos a Transplante de Células-Tronco Hematopoiéticas (TCTH) cadastrados no laboratório de HLA da Fundação Hemocentro de Ribeirão Preto, no período de janeiro de 2010 a ...
VT Santos, NHS Deghaide, GV Martins, MS Domeneghetti, EDSF Cruz   +4 more
doaj   +1 more source

Discovery of the HLA-DQB1*06:465 allele, a variant of HLA-DQB1*06:04:01:01

HLA-DQB1*06:465 differs from HLA-DQB1*06:04:01:01 by a non-synonymous nucleotide substitution in codon ...
John Jeongseok Yang, Heung-Bum Oh
core   +1 more source