Results 121 to 130 of about 21,869 (254)

In Situ Synthesis of Covalent Organic Frameworks Inside Cells for Triggering Ferroptosis and Immunotherapy

open access: yesAdvanced Materials, Volume 38, Issue 16, 17 March 2026.
We have developed an intracellular crystalline polymerization strategy involving acid‐catalyzed imine condensation to synthesize COFs in lysosomes. The generation of COFs in lysosomes damages their integrity, activates iron species, and induces immunogenic ferroptosis, thereby enhancing antitumor immunotherapy.
Qun Guan   +5 more
wiley   +1 more source

Bio‐Inspired Hierarchical Nanoreactor With Hetero‐Coordinated Fe–P–Co Bridges for Whole‐Pathway‐Regulated Electrocatalytic Oxygen Reduction

open access: yesAdvanced Materials, Volume 38, Issue 15, 12 March 2026.
A bioinspired Co‐doped Fe2P on N‐doped carbon with a hierarchical eucalyptus‐like nanoarchitecture is engineered to regulate oxygen across the entire electrochemical pathway, achieving a half‐wave potential of 0.938 V vs. RHE, sustaining 373 h of discharge in Al‐air batteries, and delivering an energy density of 3487 Wh/kg.
Qiaoling Xu   +7 more
wiley   +1 more source

The return-to-entrepreneurship puzzle. [PDF]

open access: yes
The returns to entrepreneurship are monetary and non-monetary. We offer new evidence on these returns using a large sample of genetically identical male twins.
Hyytinen, Ari   +2 more
core  

Perfluorooctanoic Acid Exposure Causes Macrophage Ammonia Retention and Induces Spontaneous Miscarriages

open access: yesAdvanced Science, Volume 13, Issue 16, 18 March 2026.
PFOA exposure induces pregnancy loss by promoting glutaminolysis, which further causes ammonia accumulation in macrophages. Cellular ammonia retention results in damage to mitochondria and lysosomes, which leads to cell death eventually. Impaired lysosomes also decrease the secretion of the Cathepsin B (CTSB), and attenuate macrophage infiltration and ...
Yongbo Zhao   +6 more
wiley   +1 more source

Prospective evaluation of low-dose ketoconazole plus hydrocortisone in docetaxel pre-treated castration-resistant prostate cancer patients. [PDF]

open access: yes, 2015
BackgroundKetoconazole is a well-known CYP17-targeted systemic treatment for castration-resistant prostate cancer (CRPC). However, most of the published data has been in the pre-chemotherapy setting; its efficacy in the post-chemotherapy setting has not ...
Beckett, LA   +6 more
core  

Navigating the Ethereal Tightrope: The Nanogenerator Manipulates Neurons for Immune Equilibrium

open access: yesAdvanced Science, Volume 13, Issue 14, 9 March 2026.
This review explores how nanogenerators modulate neuroimmune responses, offering innovative strategies for treating neurological disorders. By interfacing with neural pathways, they enable precise control of immune activity, especially via vagus nerve stimulation.
Jia Du   +5 more
wiley   +1 more source

Pearl‐Like Bioinspired Coating Enables Regulation of Mg Degradation for Osteoporotic Bone Repair

open access: yesAdvanced Science, Volume 13, Issue 13, 3 March 2026.
In this study, inspired by pearl architecture, we developed a layered Ca–P “brick” and Fn‐mimetic peptide “mortar” coating on Mg alloys. The Ca–P layer moderates corrosion and offers mineral cues, while the peptide enhances adhesion and regulates immune‐vascular responses.
Siming Zhang   +12 more
wiley   +1 more source

Influence of the Degree of Substitution of Carboxymethyl Cellulose Binders on the Properties and Performance of Aqueously Processed LiNi0.6Mn0.2Co0.2O2‐Based Positive Electrodes—A Comparative Study

open access: yesAdvanced Energy and Sustainability Research, Volume 7, Issue 3, March 2026.
Aqueous processing of positive electrodes is a crucial step toward sustainable production of lithium ion batteries. Therein, the individual properties of the binding agent can largely influence processing, the physical electrode properties, and thus, the electrochemical performance and cycle life.
Johanna Kauling   +3 more
wiley   +1 more source

CO2 Electroreduction to Multicarbon Products in Acidic Electrolyte via Structural Reconstruction of a Molybdenum Porphyrin Dimer

open access: yesAdvanced Energy and Sustainability Research, Volume 7, Issue 3, March 2026.
A novel oxo‐bridged molybdenum porphyrin dimer electrocatalyst undergoes potential‐driven structural reconstruction in acidic electrolyte, forming MoMo bonded active sites. This dynamic transformation enables selective electrochemical CO2 reduction to multicarbon products: methanol with 74% Faradaic efficiency at −1.0 V versus RHE, and ethanol with 45%
Tesfaye Alamirew Dessie   +11 more
wiley   +1 more source

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