Results 131 to 140 of about 14,145 (233)

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, Volume 38, Issue 51, 11 September 2026.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

The Prescription Patterns of Antacids in the Ambulatory Care of NHI

, 2007
在台灣人民普遍的想法看病就是要拿藥，且一直習慣認為胃藥是一種領藥時的附贈品，也幾乎在很多處方中常常都會加開胃藥。所以在服藥時，常常都配上胃藥（制酸劑）併服。很多醫師開處方時，應病人要求，也喜歡加入制酸劑，胃藥---制酸劑反而變成了一種不是很確定病人醫療需求的一種型態。再加上健保給付胃藥的幾乎全不設限，更是推波助瀾了胃藥的使用。然而有些藥物是不宜和制酸劑併服的，因此藥物與制酸劑的交互作用存在於一些藥物治療中。而如果藥品所引起的腸胃不良反應，不是因為胃酸分泌因素引起的，使用制酸劑的幫忙有限 ...
陳志明, Chen, Chih-Ming
core  

Targeting the HSPA8‐CMA‐ATP6V1A Axis Triggers Lysosomal Hyperacidification and Catastrophic Vacuolation in Prostate Cancer

Advanced Science, Volume 13, Issue 51, 14 September 2026.
Our experimental evidence supports a model in which ALO targets the HSPA8‐CMA‐ATP6V1A axis to induce lysosomal hyperacidification and initiate osmotic and lipidomic stress. These changes are associated with LMP and loss of lysosomal integrity in prostate cancer cells.
Bingzheng An, Ze Gao, Shuo Chen, Liwei Meng, Chen Zhang, Kefan Song, Haochen Cui, Lei Yan, Zhiqing Fang   +8 more
wiley   +1 more source

Nano‐Heterostructured TiO2‐TiO‐TiN/MoO3‐x‐Mo2N Composite LIB Anode With Enhanced Li+ Storage via Glycine‐assisted Anodization and Cathodic Deposition

Advanced Energy Materials, Volume 16, Issue 35, 16 September 2026.
A scalable, binder‐ and additive‐free strategy combining glycine‐assisted anodization and cathodic deposition is developed to fabricate a nano‐heterostructured composite LIB anode directly on titanium. Benefiting from its fully electrochemically active thick architecture, the anode delivers an outstanding areal capacity of 2639 µAh cm−2, nearly ...
Peng Wang, Hikaru Kaai, Jiacheng Liu, Shun Itatsu, Kohya Matsuhira, Erli Lin, Mengmeng Zhang, Shaoli Fang, Yoko Sakurai, Takashi Matsubara, Takehiko Hihara, Long Pan, Wei Zhang, ZhengMing Sun, Xiaopei Li, Song‐Zhu Kure‐Chu   +15 more
wiley   +1 more source

Effects of Different Drying Methods on the Meat Quality and Characteristic Flavor Compounds of Pacific White Shrimp

Food Frontiers, Volume 7, Issue 5, September 2026.
Different drying strategies regulated meat quality and characteristic flavor formation in Litopenaeus vannamei through distinct thermal and dehydration effects. HAFD enhanced non‐volatile umami compounds by promoting free amino acids, GMP, and EUC accumulation, whereas HAD and AFD intensified roasted‐aroma formation through pyrazines, aldehydes, esters,
Yiming Li, Nan Wang, Li Zhou, Weibin Cheng, Jiamin Song, Yanan Sun   +5 more
wiley   +1 more source

Citric Acid‑Assisted Microwave Degradation of Hericium erinaceus β‑Glucan Enhances Gastroprotective Efficacy

Food Frontiers, Volume 7, Issue 5, September 2026.
A citric acid‐assisted microwave degradation strategy was provided to enhance the therapeutic potential of H. erinaceus β‐glucan for gastric protection. ABSTRACT The gastroprotective bioactivity of high molecular‐weight β‐glucan from Hericium erinaceus is often constrained by its poor solubility and low oral bioavailability.
Peng Liu, Minjie Du, Zhong Zhang, Wanchao Chen, Wen Li, Zhengpeng Li, Dapeng Sun, Wenjian Yang, Di Wu, Yan Yang   +9 more
wiley   +1 more source

Interactions of antifungal drugs with food, beverages, antacids, and mineral supplements - protocol of a systematic review with meta-analyses

The main objectives of this systematic review are: - to investigate the impact of food, beverages, antacids, and mineral supplements on the pharmacokinetic (PK) parameters and pharmacokinetic/pharmacodynamic (PK/PD) indices of orally taken antifungal ...
Paweł Zagrodzki, Paweł Paśko, Agnieszka Wiesner   +2 more
core   +1 more source

PPI Misuse in Bangladesh: Confronting a Silent Epidemic Through Deprescribing and Regulatory Reform—A Policy Perspective

Health Science Reports, Volume 9, Issue 9, September 2026.
ABSTRACT Background and Aims Proton pump inhibitors (PPIs) are subject to rampant global misuse, posing a significant public health challenge. This issue is particularly acute in low‐ and middle‐income countries like Bangladesh, where preliminary data indicate alarmingly high rates of inappropriate prescribing, driven by systemic factors within the ...
Abdullaha Al Mamun, Md Rabiul Awual, K. A. M. Inzamul Islam   +2 more
wiley   +1 more source

Prenatal and/or childhood acid-suppressive medication use and risk of serious infections in children: A retrospective analysis of Taiwanese medical claims data. [PDF]

BMC Med
Yao TC, Hsu YL, Huang JL, Chang YC, Chang SM, Pan JJ, Hong X, Wang JY, Tsai HJ.   +8 more
europepmc   +1 more source

Inhibition of NHE1 Overcomes Temozolomide‐Resistance in Glioblastoma via ROS‐AKT/ERK Axis‐Mediated Autophagy Suppression

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 9, September 2026.
NHE1 inhibition via HOE‐642 suppresses autophagy through the ROS‐AKT/ERK axis, reversing temozolomide resistance in glioblastoma by disrupting the autophagy‐apoptosis balance and enhancing TMZ sensitivity in vitro and in vivo. ABSTRACT Glioblastoma (GBM) is the most aggressive primary brain tumor in adults, with temozolomide (TMZ) resistance being a ...
Dan Li, Yuhui Li, Xuan Zheng, Zhuo Wang, Yang Wang, Jun Zhang, Jianxiong Guo, Lei Wang, Jingwu Li, Yongliang Liu, Yufeng Li   +10 more
wiley   +1 more source