Results 271 to 280 of about 154,064 (296)
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Antibiotic Synergism and Antagonism
New England Journal of Medicine, 1951THE chemotherapeutic armamentarium of the physician has recently grown considerably. The question is no longer merely whether to give penicillin; the choice must now be made among half a dozen or more efficient antimicrobial agents that can be used to advantage in many infectious processes. With the availability of several good drugs the idea naturally
Ernest Jawetz +2 more
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Antagonism of Guanethidine by Chlorpromazine
American Journal of Psychiatry, 1973Chlorpromazine was found to reverse the antihypertensive effects of guanethidine six times in use with four moderately or severely hypertensive psychiatric patients. Haloperidol and thiothixene caused similar effects. It is postulated that this drug-drug interaction occurs because chlorpromazine blocks the neuronal amine-guanethidine uptake pump ...
William E. Fann +3 more
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Benzodiazepine antagonism by aminophylline
Acta Anaesthesiologica Scandinavica, 1989A double–blind, randomised study was performed to investigate whether aminophylline could reverse the sedative effect of benzodiazepine and if it could shorten the observation time necessary after benzodiazepine sedation. Forty patients undergoing minor abdominal, urogenital or lower extremity surgery were given benzodiazepine to maintain a state of ...
C. Pedersen +4 more
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Digitoxin Antagonism by Visnadin
Journal of Pharmaceutical Sciences, 1962Visnadin, a lactone derived from bishop's weed, has been found to have marked antidotal properties in animals poisoned with digitoxin. It increases survival on acute and chronic administration of the glycoside, prevents the appearance of bradycardia, and reverses cardiac arrhythmias.
D.D. Varonos +2 more
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World Futures, 1994
Abstract Distributed artificial intelligence (DAI) aims to solve problems using cooperation between real or abstract entities. The transition from artificial intelligence (AI) to distributed artificial intelligence poses the problem of transition from an individualistic to a collective concept.
Ph. Benhamou, J. Erceau
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Abstract Distributed artificial intelligence (DAI) aims to solve problems using cooperation between real or abstract entities. The transition from artificial intelligence (AI) to distributed artificial intelligence poses the problem of transition from an individualistic to a collective concept.
Ph. Benhamou, J. Erceau
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2006
This chapter discusses how the real time relative kinetics of agonist and antagonist offset from the receptor determines whether or not orthosteric antagonists produce competitive, a hemi-equilibrium state or non-competitive antagonism. These kinetics effects also are discussed in terms of the target coverage produced in vivo.
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This chapter discusses how the real time relative kinetics of agonist and antagonist offset from the receptor determines whether or not orthosteric antagonists produce competitive, a hemi-equilibrium state or non-competitive antagonism. These kinetics effects also are discussed in terms of the target coverage produced in vivo.
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Endothelin Receptor Antagonism
1995Following the original report by Yanagisawa et al. (1988) more than 7 years ago, compelling evidence that ET plays an important role in the local regulation of smooth muscle tone and cell growth has been reported. In addition, many studies point to a significant role for endothelin in nonvascular function. The investigation of the endothelin system has
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