Results 61 to 70 of about 182,741 (305)
Frontiers in Microbiology, 2020 The invasive ascomycete Hymenoscyphus fraxineus has been threatening Fraxinus excelsior populations throughout Europe for over two decades. Since the infection and first colonization by the pathogen occurs in leaves, leaf-colonizing microorganisms have ...
Regina Becker +4 more
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Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Sexual antagonism in sequential hermaphrodites [PDF]
, 2023 Funding: H2020 European Research Council - European Research Council Consolidator Grant (771387; Natural Environment Research Council - Independent Research Fellowship (NE/K009524/1); RIKEN - Special Postdoctoral Researchers Program; University of St ...
Hitchcock, Thomas James, Gardner, Andy
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Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Class, contradiction and antagonism
, 2023 The indistinction between contradiction and antagonism also characterizes the conceptualization of class in open Marxism. In this chapter we recover the notion of class as an antagonistic social relation, but we try to show that its most fruitful ...
Piva, Adrián
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European Review of Latin American and Caribbean Studies, 2009 In many countries of Latin America, and particularly in Argentina, the 1990s are commonly characterized by the so-called triumph of the ideology of neoliberalism. This inclination was highly counteracted in rhetoric as well as in action. Free markets and
María Antonia Muñoz
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Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Herbicide Antagonism at the Whole Plant Level
, 1989 Antagonistic interactions between herbicides or between herbicides and nonherbicides are common and prevent the use of certain mixtures. Although antagonism is detrimental when it reduces weed control, the degree of antagonism is critical to determine ...
Jerome M. Green
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Acta Agronómica, 2008 El efecto de las épocas de lluvia y sequía sobre la absorción de potasio y fósforo en plantaciones de plátano (Musa AAB) Simmonds se evaluó en cuatro unidades geomorfológicas de suelo en el municipio de Moñitos (Córdoba) utilizando un muestreo al azar ...
José L. Barrera V +3 more
doaj
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source