Results 1 to 10 of about 1,040,427 (369)

Luteinizing hormone profiles during ovarian stimulation in assisted reproductive treatment [PDF]

open access: yesFrontiers in Endocrinology
IntroductionFew data is available on the natural course of luteinizing hormone (LH) during ovarian stimulation, but it has been suggested that ‘oversuppressed’ LH could decrease fertility outcomes. Our aim with this study is to evaluate the changes in LH
Hannah Verschuere   +7 more
doaj   +2 more sources

First Molecular Characterization of sp. and sp. Isolated from Mangrove in Mexico and the Antagonist Effect of as an Effective Biocontrol Agent [PDF]

open access: yesThe Plant Pathology Journal, 2021
The aim of this study was to characterize potential fungal species affecting mangrove species in Mexico. The phytopathogens were identified based on morphological and molecular characteristics using internal transcribed spacer (ITS1/ITS4) primers then ...
Mayra I. Grano-Maldonado   +6 more
doaj   +1 more source

Filling the Gaps in Antagonist CCR5 Binding, a Retrospective and Perspective Analysis

open access: yesFrontiers in Immunology, 2022
The large number of pathologies that position CCR5 as a central molecular determinant substantiates the studies aimed at understanding receptor-ligand interactions, as well as the development of compounds that efficiently block this receptor.
Yerkezhan Amerzhanova, Luca Vangelista
doaj   +1 more source

Generation of KS-133 as a Novel Bicyclic Peptide with a Potent and Selective VIPR2 Antagonist Activity that Counteracts Cognitive Decline in a Mouse Model of Psychiatric Disorders

open access: yesFrontiers in Pharmacology, 2021
Worldwide, more than 20 million people suffer from schizophrenia, but effective and definitive new therapeutic drugs/treatments have not been established.
Kotaro Sakamoto   +16 more
doaj   +1 more source

Design, synthesis and biological evaluation of novel biphenylsulfonamide derivatives as selective AT2 receptor antagonists

open access: yesFrontiers in Chemistry, 2022
A novel series of benzenesulfonamide derivatives that selectively act on the AT2 receptor have been designed and synthesized. The binding affinity and functional activity were evaluated by radio-ligand binding analysis and cell neurite outgrowth assay ...
Danhui Wang   +7 more
doaj   +1 more source

Sleep-promoting activity of lotus (Nelumbo nucifera) rhizome water extract via GABAA receptors

open access: yesPharmaceutical Biology, 2022
Context The sleep-promoting activity of Nelumbo nucifera Gaertn. (Nymphaeaceae) alkaloids in leaves or seeds are well known. However, the sleep-promoting activity of the lotus rhizome (LE), which is used mainly as food, has not yet been evaluated ...
Yejin Ahn   +5 more
doaj   +1 more source

Prolactin receptor signaling: A novel target for cancer treatment - Exploring anti-PRLR signaling strategies

open access: yesFrontiers in Endocrinology, 2023
Prolactin (PRL) is a peptide hormone mainly secreted from the anterior pituitary gland. PRL is reported to play a role in pregnancy, mammary gland development, immune modulation, reproduction, and differentiation of islet cells. PRL binds to its receptor
David Standing   +2 more
doaj   +1 more source

ACTH Antagonists [PDF]

open access: yesFrontiers in Endocrinology, 2016
Adrenocorticotropin (ACTH) acts via a highly selective receptor that is a member of the melanocortin receptor subfamily of type 1 G protein-coupled receptors. The ACTH receptor, also known as the melanocortin 2 receptor (MC2R), is unusual in that it is absolutely dependent on a small accessory protein, melanocortin receptor accessory protein (MRAP) for
Clark, AJ   +6 more
openaire   +4 more sources

Targeting TNFR2 in Cancer: All Roads Lead to Rome

open access: yesFrontiers in Immunology, 2022
TNF receptor 2 (TNFR2) has become one of the best potential immune checkpoints that might be targeted, mainly because of its vital role in tumor microenvironments (TMEs).
Jingchao Bai   +8 more
doaj   +1 more source

Inhibitory effects of antagonistic bacteria inhabiting the rhizosphere of the sugarbeet plants, on Cercospora beticola Sacc., the causal agent of Cercospora leaf spot disease on sugarbeet

open access: yesJournal of Plant Protection Research, 2016
In the present study, the antagonistic capability of bacterial agents inhabiting the rhizosphere of sugarbeet plants were evaluated against Cercospora beticola Sacc. under laboratory and greenhouse conditions.
Arzanlou Mahdi   +4 more
doaj   +1 more source

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