Results 1 to 10 of about 1,549,522 (343)
Frontiers in Pharmacology, 2023 Background and purpose: GPR35, a member of the orphan G-protein-coupled receptor, was recently implicated in colorectal cancer (CRC). However, whether targeting GPR35 by antagonists can inhibit its pro-cancer role has yet to be answered.Experimental ...
Wuxiyar Otkur +9 more
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Frontiers in Pharmacology, 2021 Worldwide, more than 20 million people suffer from schizophrenia, but effective and definitive new therapeutic drugs/treatments have not been established.
Kotaro Sakamoto +16 more
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Frontiers in Endocrinology, 2023 Prolactin (PRL) is a peptide hormone mainly secreted from the anterior pituitary gland. PRL is reported to play a role in pregnancy, mammary gland development, immune modulation, reproduction, and differentiation of islet cells. PRL binds to its receptor
David Standing +2 more
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Frontiers in Endocrinology, 2023 BackgroundAndrogen deprivation therapy is the mainstay of medical treatment for prostate cancer (Pca); however, it is associated with an increased risk of adverse cardiovascular (CV) events and death.
Li Gu, Xurui Li, Wentao Liu
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First Molecular Characterization of sp. and sp. Isolated from Mangrove in Mexico and the Antagonist Effect of as an Effective Biocontrol Agent [PDF]
The Plant Pathology Journal, 2021 The aim of this study was to characterize potential fungal species affecting mangrove species in Mexico. The phytopathogens were identified based on morphological and molecular characteristics using internal transcribed spacer (ITS1/ITS4) primers then ...
Mayra I. Grano-Maldonado +6 more
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Modern aspects in anesthesia of small laboratory animals
Южно-Российский онкологический журнал, 2022 Experiments with small laboratory animals are required for better understanding of a disease flow, for studying the mechanisms of it’s development and for the development of new therapeutic strategies.
S. V. Gurova +2 more
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Frontiers in Immunology, 2023 Chemokine G-protein coupled receptors are validated drug targets for many diseases, including cancer, neurological, and inflammatory disorders. Despite much time and effort spent on therapeutic development, very few chemokine receptor antagonists are ...
Patrick Grudzien +3 more
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Structure, Function, and Pharmaceutical Ligands of 5-Hydroxytryptamine 2B Receptor
Pharmaceuticals, 2021 Since the first characterization of the 5-hydroxytryptamine 2B receptor (5-HT2BR) in 1992, significant progress has been made in 5-HT2BR research. Herein, we summarize the biological function, structure, and small-molecule pharmaceutical ligands of the 5-
Qing Wang +3 more
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Interaction of GABA and Excitatory Amino Acids in the Basolateral Amygdala: Role in Cardiovascular Regulation [PDF]
, 1997 Activation of the amygdala in rats produces cardiovascular changes that include increases in heart rate and arterial pressure as well as behavioral changes characteristic of emotional arousal.
Cook, Jennifer C. +3 more
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Frontiers in Molecular Neuroscience, 2018 The Wingless (Wnt)-mediated signals are involved in many important aspects of development of the mammalian cerebral cortex. How Wnts interact with their modulators in cortical development is still unclear.
Nan Miao +8 more
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