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First Molecular Characterization of sp. and sp. Isolated from Mangrove in Mexico and the Antagonist Effect of as an Effective Biocontrol Agent [PDF]
The Plant Pathology Journal, 2021 The aim of this study was to characterize potential fungal species affecting mangrove species in Mexico. The phytopathogens were identified based on morphological and molecular characteristics using internal transcribed spacer (ITS1/ITS4) primers then ...
Mayra I. Grano-Maldonado +6 more
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Microorganisms, 2022 Infectious diseases are still a major problem worldwide. This includes microbial infections, with a constant increase in resistance to the current anti-infectives employed. Toll-like receptors (TLRs) perform a fundamental role in pathogen recognition and
Helena Merk +8 more
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Sleep-promoting activity of lotus (Nelumbo nucifera) rhizome water extract via GABAA receptors
Pharmaceutical Biology, 2022 Context The sleep-promoting activity of Nelumbo nucifera Gaertn. (Nymphaeaceae) alkaloids in leaves or seeds are well known. However, the sleep-promoting activity of the lotus rhizome (LE), which is used mainly as food, has not yet been evaluated ...
Yejin Ahn +5 more
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Frontiers in Endocrinology, 2016 Adrenocorticotropin (ACTH) acts via a highly selective receptor that is a member of the melanocortin receptor subfamily of type 1 G protein-coupled receptors. The ACTH receptor, also known as the melanocortin 2 receptor (MC2R), is unusual in that it is absolutely dependent on a small accessory protein, melanocortin receptor accessory protein (MRAP) for
Clark, AJ +6 more
openaire +4 more sources
Modern aspects in anesthesia of small laboratory animals
Южно-Российский онкологический журнал, 2022 Experiments with small laboratory animals are required for better understanding of a disease flow, for studying the mechanisms of it’s development and for the development of new therapeutic strategies.
S. V. Gurova +2 more
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Intellectual Capital and Chaos of Innovation: Antagonist Coalition in Organizations
Istanbul Management Journal, 2023 As a critical resource of human capital, employees might be the leading supporters of innovation management considering the integrated intellectual capital.
Asiye Yüksel
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The newly developed CRF1-receptor antagonists, NGD 98-2 and NGD 9002, suppress acute stress-induced stimulation of colonic motor function and visceral hypersensitivity in rats. [PDF]
, 2013 Corticotropin releasing factor receptor 1 (CRF1) is the key receptor that mediates stress-related body responses. However to date there are no CRF1 antagonists that have shown clinical efficacy in stress-related diseases.
Czimmer, József +7 more
core +11 more sources
Pyrrolotriazinone as an Underexplored Scaffold in Drug Discovery
Pharmaceuticals, 2021 Heterocyclic amino derivatives have been extensively synthesized and validated as potent bioactive compounds, and nowadays, numerous marketed drugs share these scaffolds, from very simple structures (monoamino, monocyclic compounds) to much more complex ...
Tony Ge, Jean-Christophe Cintrat
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Cells, 2020 Prostate cancer (PCa) is the most frequently diagnosed cancer in men, causing considerable morbidity and mortality. The P2X4 receptor (P2X4R) is the most ubiquitously expressed P2X receptor in mammals and is positively associated with tumorigenesis in ...
Jiepei He +9 more
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Frontiers in Endocrinology, 2023 Prolactin (PRL) is a peptide hormone mainly secreted from the anterior pituitary gland. PRL is reported to play a role in pregnancy, mammary gland development, immune modulation, reproduction, and differentiation of islet cells. PRL binds to its receptor
David Standing +2 more
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