Results 31 to 40 of about 1,056,606 (342)

Role of dopamine D1-like receptors in methamphetamine locomotor responses of D2 receptor knockout mice [PDF]

, 2008
Behavioral sensitization to psychostimulants manifests as an increased locomotor response with repeated administration. Dopamine systems are accepted to play a fundamental role in sensitization, but the role of specific dopamine receptor subtypes has not
Atkins, Baik, Battisti, Battisti, Boileau, Cador, Chiang, Crabbe, Crawford, de Wit, Down, Fleckenstein, Gabbay, Glickstein, Hamamura, Jones, Kalivas, Kamens, Karler, Karper, Kelly, Kelly, Kilty, Kuczenski, Kuribara, Kuribara, Kuribara, McDougall, Neve, Palmer, Phillips, Phillips, Pierce, Robinson, Ron, Rubinstein, Sax, Schmauss, Shen, Tanabe, Ujike, Vezina, Vezina, Xu, Xu, Xu, Xu, Yates   +47 more
core   +1 more source

Structural basis for the antiviral activity of BST-2/tetherin and its viral antagonism

Frontiers in Microbiology, 2011
The interferon-inducible host restriction factor bone marrow stromal antigen 2 (BST-2/tetherin) blocks the release of HIV-1 and other enveloped viruses.
Juan F. eArias, Yukie eIwabu, Kenzo eTokunaga   +2 more
doaj   +1 more source

Generation of KS-133 as a Novel Bicyclic Peptide with a Potent and Selective VIPR2 Antagonist Activity that Counteracts Cognitive Decline in a Mouse Model of Psychiatric Disorders

Frontiers in Pharmacology, 2021
Worldwide, more than 20 million people suffer from schizophrenia, but effective and definitive new therapeutic drugs/treatments have not been established.
Kotaro Sakamoto, Lu Chen, Tatsunori Miyaoka, Mei Yamada, Teruaki Masutani, Kenji Ishimoto, Kenji Ishimoto, Kenji Ishimoto, Nobumasa Hino, Shinsaku Nakagawa, Shinsaku Nakagawa, Shinsaku Nakagawa, Satoshi Asano, Yukio Ago, Yukio Ago, Yukio Ago, Yukio Ago   +16 more
doaj   +1 more source

Seminal plasma and prostaglandin E2 up-regulate fibroblast growth factor 2 expression in endometrial adenocarcinoma cells via E-series prostanoid-2 receptor-mediated transactivation of the epidermal growth factor receptor and extracellular signal-regulated kinase pathway [PDF]

, 2006
We report a multiwavelength (X-ray, ultraviolet/optical/infrared, radio) analysis of the relativistic tidal disruption event candidate Sw J2058+05 from 3 months to 3 yr post-discovery in order to study its properties and compare its behavior with that of
Bower, Geoffrey C., Brown, Gregory C., Cenko, S. Bradley, Dolan, Stephen, Filippenko, Alexei V., Fruchter, Andrew S., Greiner, Jochen, Horesh, Assaf, Hounsell, Rebekah A., Levan, Andrew J., O'Brien, Paul T., Page, Kim L., Pasham, Dheeraj R., Rau, Arne, Tanvir, Nial R., Wiersema, Klaas   +15 more
core   +2 more sources

Microbes vs. Nematodes: Insights into Biocontrol through Antagonistic Organisms to Control Root-Knot Nematodes

Plants, 2023
Root-knot nematodes (Meloidogyne spp.) are sedentary endoparasites that cause severe economic losses to agricultural crops globally. Due to the regulations of the European Union on the application of nematicides, it is crucial now to discover eco ...
Adil Ameen Bhat, Adnan Shakeel, Sonia Waqar, Zafar Ahmad Handoo, Abrar Ahmed Khan   +4 more
doaj   +1 more source

Efektivitas Isolat Bakteri dari Rizosfer dan Bahan Organik Terhadap Ralstonia solanacearum dan Fusarium oxysporum pada Tanaman Kentang

Jurnal Fitopatologi Indonesia, 2014
Rhizosphere is an ideal area for growth and development of microbial antagonists, because it is a nutrition rich area. Nutrients that secreted in the rhizosphere are influenced by many environmental factors which in turn effect the diversity and ...
Tutik Kuswinanti, Baharuddin Baharuddin, Sri Sukmawati   +2 more
doaj   +1 more source

Emergence of an Auxin Sensing Domain in Plant-Associated Bacteria

mBio, 2023
Bacteria have evolved a sophisticated array of signal transduction systems that allow them to adapt their physiology and metabolism to changing environmental conditions. Typically, these systems recognize signals through dedicated ligand binding domains (
José A. Gavira, Miriam Rico-Jiménez, Álvaro Ortega, Natalia V. Petukhova, Dmitrii S. Bug, Albert Castellví, Yuri B. Porozov, Igor B. Zhulin, Tino Krell, Miguel A. Matilla   +9 more
doaj   +1 more source

Micro-RNA family that modulates fibrosis and uses thereof [PDF]

, 2017
The present invention relates to the identification of a microRNA family, designated miR-29a-c, that is a key regulator of fibrosis in cardiac tissue. The inventors show that members of the miR-29 family are down-regulated in the heart tissue in response
Olson, Eric N., van Rooij, Eva
core   +1 more source

Endemic Jeffrey Pine Beetle Associates: Beetle/Mite Fungal Dissemination Strategies and Interactions That May Influence Beetle Population Levels

Microorganisms, 2021
Fungal and mite associates may drive changes in bark beetle populations, and mechanisms constraining beetle irruptions may be hidden in endemic populations.
Javier E. Mercado, Beatriz Ortiz-Santana, Shannon L. Kay   +2 more
doaj   +1 more source

Design, synthesis and biological evaluation of novel biphenylsulfonamide derivatives as selective AT2 receptor antagonists

Frontiers in Chemistry, 2022
A novel series of benzenesulfonamide derivatives that selectively act on the AT2 receptor have been designed and synthesized. The binding affinity and functional activity were evaluated by radio-ligand binding analysis and cell neurite outgrowth assay ...
Danhui Wang, Wenjie Zhao, Zuzhi Zhang, Yanchun Zhang, Yanchun Zhang, Jiaming Li, Jiaming Li, Weijun Huang   +7 more
doaj   +1 more source