Results 31 to 40 of about 1,481,945 (415)
Kinin-B1 receptors in ischaemia-induced pancreatitis: Functional importance and cellular localisation [PDF]
, 2003 In this study we compare the role of kininB1 and B2 receptors during ischaemia/reperfusion of rat pancreas. Our investigations were prompted by the observation that infusion of a kininB2 receptor antagonist produced significant improvement in acute ...
Ahluwalia A. +9 more
core +1 more source
Jurnal Fitopatologi Indonesia, 2014 Rhizosphere is an ideal area for growth and development of microbial antagonists, because it is a nutrition rich area. Nutrients that secreted in the rhizosphere are influenced by many environmental factors which in turn effect the diversity and ...
Tutik Kuswinanti +2 more
doaj +1 more source
Percolation on interdependent networks with a fraction of antagonistic interactions [PDF]
Journal of Statistical Physics, 152,1069 (2013), 2013 Recently, the percolation transition has been characterized on interacting networks both in presence of interdependent and antagonistic interactions. Here we characterize the phase diagram of the percolation transition in two Poisson interdependent networks with a percentage q of antagonistic nodes. We show that this system can present a bistability of
arxiv +1 more source
Predicted Structures and Dynamics for Agonists and Antagonists Bound to Serotonin 5-HT2B and 5-HT2C Receptors [PDF]
, 2011 Subtype 2 serotonin (5-hydroxytryptamine, 5-HT) receptors are major drug targets for schizophrenia, feeding disorders, perception, depression, migraines, hypertension, anxiety, hallucinogens, and gastrointestinal dysfunctions.' We report here ...
Abrol, Ravinder +4 more
core +2 more sources
Frontiers in Pharmacology, 2011 Receptors for sphingosine-1-phosphate (S1P) have been identified only recently. Their medicinal chemistry is therefore still in its infancy, and few selective agonists or antagonists are available. Furthermore, the selectivity of S1P receptor agonists or
Christian eWaeber, Salvatore eSalomone
doaj +1 more source
Crystal structure of the μ-opioid receptor bound to a morphinan antagonist
Nature, 2012 Opium is one of the world’s oldest drugs, and its derivatives morphine and codeine are among the most used clinical drugs to relieve severe pain. These prototypical opioids produce analgesia as well as many undesirable side effects (sedation, apnoea and ...
A. Manglik +9 more
semanticscholar +1 more source
The Histamine H3 Receptor Antagonist DL77 Ameliorates MK801-Induced Memory Deficits in Rats
Frontiers in Neuroscience, 2018 The role of Histamine H3 receptors (H3Rs) in memory, and the prospective of H3R antagonists in pharmacological control of neurodegenerative disorders, e.g., Alzheimer disease (AD) is well-accepted.
Nermin Eissa +5 more
doaj +1 more source
Frontiers in Endocrinology, 2013 The stimulatory effects of ghrelin, a 28-AA acylated peptide originally isolated from stomach, on GH secretion and feeding are exclusively mediated through the growth hormone secretagogue 1a receptor (GHS-R1a), the only ghrelin receptor described so far.
Rim eHassouna +6 more
doaj +1 more source
Applicability of the National Comprehensive Cancer Network/Multinational Association of Supportive Care in Cancer Guidelines for Prevention and Management of Chemotherapy-Induced Nausea and Vomiting in Southeast Asia: A Consensus Statement. [PDF]
, 2017 A meeting of regional experts was convened in Manila, Philippines, to develop a resource-stratified chemotherapy-induced nausea and vomiting (CINV) management guideline. In patients treated with highly emetogenic chemotherapy in general clinical settings,
Abdullah, Matin M +5 more
core +2 more sources
Cells, 2020 Prostate cancer (PCa) is the most frequently diagnosed cancer in men, causing considerable morbidity and mortality. The P2X4 receptor (P2X4R) is the most ubiquitously expressed P2X receptor in mammals and is positively associated with tumorigenesis in ...
Jiepei He +9 more
doaj +1 more source