Results 41 to 50 of about 1,519,714 (391)

Actinobacteria from avocado rhizosphere: antagonistic activity against Colletotrichum gloeosporioides and Xanthomonas sp.

open access: yesTerra Latinoamericana, 2021
Actinobacteria from the rhizosphere of agricultural crops are a potential source of antagonists against phytopathogenic microorganisms. Thus, the objective of this study was to characterize the antagonistic activity in vitro of actinobacteria from the ...
Jesús Rafael Trinidad-Cruz   +6 more
doaj   +1 more source

Involvement of Noradrenergic Neurotransmission in the Stress- but not Cocaine-Induced Reinstatement of Extinguished Cocaine-Induced Conditioned Place Preference in Mice: Role for β-2 Adrenergic Receptors [PDF]

open access: yes, 2010
The responsiveness of central noradrenergic systems to stressors and cocaine poses norepinephrine as a potential common mechanism through which drug re-exposure and stressful stimuli promote relapse.
A Dzung Lê   +86 more
core   +3 more sources

Antagonist targeting microRNA-155 protects against lithium-pilocarpine-induced status epilepticus in C57BL/6 mice by activating brain-derived neurotrophic factor

open access: yesFrontiers in Pharmacology, 2016
Epilepsy is a severe brain disorder affecting numerous patients. Recently, it is inferred that modulation of microRNA-155 (miR-155) could serve as a promising treatment of mesial temporal lobe epilepsy (MTLE).
Zhengxu eCai   +11 more
doaj   +1 more source

Broader Estimates of Gastrocnemius Activity Generated a More Representative Cocontraction Index: A Study in Pediatric Population

open access: yesIEEE Transactions on Neural Systems and Rehabilitation Engineering, 2023
The electromyography (EMG) cocontraction index (CCI) given by the antagonistic/agonistic Root Mean Square (RMS) amplitude ratio of the same muscle is a qualified biomarker used for spastic cocontraction quantification and management in cerebral palsy ...
Maria Vinti   +5 more
doaj   +1 more source

Non-equivalence of key positively charged residues of the free fatty acid 2 receptor in the recognition and function of agonist versus antagonist ligands [PDF]

open access: yes, 2015
Short chain fatty acids (SCFAs) are produced in the gut by bacterial fermentation of poorly digested carbohydrates. A key mediator of their actions is the G protein-coupled Free Fatty Acid 2 (FFA2) receptor and this has been suggested as a therapeutic ...
Hansen, Anders Højgaard   +6 more
core   +1 more source

Pharmacological characterization of rat paw edema induced by Cerastes gasperettii (cerastes) venom

open access: yesJournal of Venomous Animals and Toxins including Tropical Diseases, 2006
Inflammatory response induced by the venom of the Arabian sand viper Cerastes gasperettii was studied by measuring rat hind-paw edema. Cerastes gasperettii venom (CgV, 3.75-240 µg/paw), heated for 30s at 97°C, caused a marked dose and time-dependent ...
A. K. Al-Asmari, N. M. Abdo
doaj   +1 more source

Interactions of narcotic antagonists and antagonist-analgesics

open access: yesJournal of Pharmacy and Pharmacology, 1968
Abstract In the rat the potent narcotic antagonist N-cyclopropylmethyl-6,14-endoethano-7α- (1-hydroxy-1-methylethyl)-tetrahydronororipavine (M5050, Reckitt), which itself lacks analgesic activity, resembled naloxone in its capacity to reverse the antinociceptive effects of morphine antagonist-analgesics. The nociceptive stimulus employed
G F Blane, D Dugdall
openaire   +3 more sources

Antagonists to the rescue [PDF]

open access: yesJournal of Clinical Investigation, 2000
Errors in protein folding represent the underlying basis for a large number of genetically inherited diseases. Point mutations, deletions, and in some cases, expanded sequences of amino acids give rise to protein products that fail to reach their native folded state.
Marybeth Howard, William J. Welch
openaire   +3 more sources

Discovery and Structure-Based Optimization of 6-Bromotryptamine Derivatives as Potential 5-HT2A Receptor Antagonists

open access: yesMolecules, 2015
5-Hydroxytryptamine type 2A (5-HT2A) receptor is an important target for developing innovative antipsychotic agents in neuropsychiatric disorder therapies.
Lijian Ding   +8 more
doaj   +1 more source

Receptor modulators associated with the hypothalamus -pituitary-thyroid axis

open access: yesFrontiers in Pharmacology, 2023
The hypothalamus-pituitary-thyroid (HPT) axis maintains normal metabolic balance and homeostasis in the human body through positive and negative feedback regulation.
Xianbin Cheng   +7 more
doaj   +1 more source

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