Results 41 to 50 of about 910,715 (290)

Antagonists of Evil in the Works of J. R. R. Tolkien and Nato Davitashvili

open access: yesNalans, 2021
The article deals with the main characteristics of the antagonists in Fantasy literature. Evil characters have always existed in different literary works. However, in fantasy literature the main antagonist is definitely evil.
Tamar Katamadze
doaj  

Emergence of an Auxin Sensing Domain in Plant-Associated Bacteria

open access: yesmBio, 2023
Bacteria have evolved a sophisticated array of signal transduction systems that allow them to adapt their physiology and metabolism to changing environmental conditions. Typically, these systems recognize signals through dedicated ligand binding domains (
José A. Gavira   +9 more
doaj   +1 more source

Viewpoint on handling anti-TNF failure in psoriasis [PDF]

open access: yes, 2013
An association among the occurrence of antidrug antibodies (ADAs), diminished trough serum drug levels (TSDLs) and non-response or loss of response has been described for several tumor necrosis factor alpha (TNF) blocking agents in a variety of diseases,
BRACKE, STEFANIE, Lambert, Jo
core   +1 more source

THE ANTIFUNGAL ACTIVITY OF ENDOPHYTE FUNGUS FROM RUBBER LEAVES IN VITRO AND ITS ANTAGONIST MECHANISM OF COLLETOTRICHUM GLOEOSPORIOIDES

open access: yesRussian Journal of Agricultural and Socio-Economic Sciences, 2021
Rubber tree disease is the most important disturbing factor compared to other disorders. There have been found 25 types of diseases in rubber estate, and the most important one is Colletotrichum leaf spot caused by Colletotrichum gloesporioides. Recently,
Syamsafitri   +3 more
doaj   +1 more source

Endemic Jeffrey Pine Beetle Associates: Beetle/Mite Fungal Dissemination Strategies and Interactions That May Influence Beetle Population Levels

open access: yesMicroorganisms, 2021
Fungal and mite associates may drive changes in bark beetle populations, and mechanisms constraining beetle irruptions may be hidden in endemic populations.
Javier E. Mercado   +2 more
doaj   +1 more source

Effect of the glucocorticoid receptor antagonist Org 34850 on fast and delayed feedback of corticosterone release [PDF]

open access: yes, 2007
We investigated the effect of the glucocorticoid receptor (GR) antagonist Org 34850 on fast and delayed inhibition of corticosterone secretion in response to the synthetic glucocorticoid methylprednisolone (MPL).
Craighead, Mark   +7 more
core   +1 more source

Alveolar Soft Part Sarcoma in Pediatric and Young Adult Patients: A Report From the Children's Oncology Group Study ARST0332

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Alveolar soft part sarcoma (ASPS) is a rare soft tissue sarcoma occurring most commonly in adolescence and young adulthood. Methods We present the clinical characteristics, treatments, and outcomes of patients with newly diagnosed ASPS enrolled on the Children's Oncology Group study ARST0332.
Jacquelyn N. Crane   +11 more
wiley   +1 more source

Design, synthesis and biological evaluation of novel biphenylsulfonamide derivatives as selective AT2 receptor antagonists

open access: yesFrontiers in Chemistry, 2022
A novel series of benzenesulfonamide derivatives that selectively act on the AT2 receptor have been designed and synthesized. The binding affinity and functional activity were evaluated by radio-ligand binding analysis and cell neurite outgrowth assay ...
Danhui Wang   +7 more
doaj   +1 more source

Cannabinoid Receptor Involvement in Stress-Induced Cocaine Reinstatement: Potential Interaction with Noradrenergic Pathways [PDF]

open access: yes, 2012
This study examined the role of endocannabinoid signaling in stress-induced reinstatement of cocaine seeking and explored the interaction between noradrenergic and endocannabinergic systems in the process.
Hillard, Cecilia J.   +6 more
core   +2 more sources

A PRSZT Registry Analysis of Prognostic Factors Influencing Survival and Relapse Rates After Second Allogeneic Hematopoietic Stem Cell Transplantation in Pediatric Acute Lymphoblastic Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT A second allogeneic (allo‐)hematopoietic stem cell transplantation (HSCT2) is a potential curative option for pediatric patients with acute lymphoblastic leukemia (ALL) following relapse after first allogeneic transplantation (HSCT1), but its efficacy is limited by high relapse rates and transplant‐related toxicity in highly pretreated ...
Ava Momm   +10 more
wiley   +1 more source

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