Results 61 to 70 of about 1,012,981 (340)
Intellectual Capital and Chaos of Innovation: Antagonist Coalition in Organizations
Istanbul Management Journal, 2023 As a critical resource of human capital, employees might be the leading supporters of innovation management considering the integrated intellectual capital.
Asiye Yüksel
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Making tau amyloid models in vitro: a crucial and underestimated challenge
FEBS Letters, EarlyView.This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
Structure-based analysis of the ultraspiracle protein and docking studies of putative ligands
Journal of Insect Science, 2002 The ultraspiracle protein (USP) is the insect ortholog of the mammalian retinoid X receptor (RXR). Fundamental questions concern the functional role of USP as the heterodimerization partner of insect nuclear receptors such as the ecdysone receptor.
Souphatta Sasorith +4 more
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AgricultureSustainable plant production requires less use of synthetic chemicals in plant nutrition and protection. Microbial products are among the most promising substitutes for chemicals.
Alaa Abdulkadhim A. Almuslimawi +4 more
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Galanin receptor 2 modifies neuropeptide Y Y1 receptor internalization and β-Arrestin recruitment [PDF]
, 2015 We have recently described a Galanin receptor 2(GALR2) and Neuropeptide Y Y1 receptor(NPYY1R) interaction at behavioural, cellular and receptor levels through GALR2/NPYY1R heterodimers.
Borroto-Escuela, Dasiel +8 more
core
FEBS Letters, EarlyView.In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
Pyrrolotriazinone as an Underexplored Scaffold in Drug Discovery
Pharmaceuticals, 2021 Heterocyclic amino derivatives have been extensively synthesized and validated as potent bioactive compounds, and nowadays, numerous marketed drugs share these scaffolds, from very simple structures (monoamino, monocyclic compounds) to much more complex ...
Tony Ge, Jean-Christophe Cintrat
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Indomethacin-antihistamine combination for gastric ulceration control [PDF]
, 1981 An anti-inflammatory and analgesic composition containing indomethacin and an H sub 1 or an H sub 2 histamine receptor antagonist in an amount sufficient to reduce gastric distress caused by the indomethacin is described.
Brown, P. A., Danellis, J. V.
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A stepwise emergence of evolution in the RNA world
FEBS Letters, EarlyView.How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley +1 more source
Russian Journal of Agricultural and Socio-Economic Sciences, 2021 Rubber tree disease is the most important disturbing factor compared to other disorders. There have been found 25 types of diseases in rubber estate, and the most important one is Colletotrichum leaf spot caused by Colletotrichum gloesporioides. Recently,
Syamsafitri +3 more
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