Results 81 to 90 of about 1,056,606 (342)

Inhibitory effects of antagonistic bacteria inhabiting the rhizosphere of the sugarbeet plants, on Cercospora beticola Sacc., the causal agent of Cercospora leaf spot disease on sugarbeet

Journal of Plant Protection Research, 2016
In the present study, the antagonistic capability of bacterial agents inhabiting the rhizosphere of sugarbeet plants were evaluated against Cercospora beticola Sacc. under laboratory and greenhouse conditions.
Arzanlou Mahdi, Mousavi Somayeh, Bakhshi Mounes, Khakvar Reza, Bandehagh Ali   +4 more
doaj   +1 more source

Endothelin receptor B antagonists decrease glioma cell viability independently of their cognate receptor [PDF]

, 2008
Background: Endothelin receptor antagonists inhibit the progression of many cancers, but research into their influence on glioma has been limited. Methods: We treated glioma cell lines, LN-229 and SW1088, and melanoma cell lines, A375 and WM35 ...
A Bagnato, A Bagnato, AV Budanov, D Salani, ER Levin, F Spinella, G Egidy, G Pan, H Peeters, H Walczak, HT Adler, J Eberle, J Nelson, JB Nelson, JD Stiles, Jennifer P Montgomery, JP Sheridan, JR Wu-Wong, K Ishikawa, K Kikuchi, K Takahashi, L Rosano, L Rosano, M Matsumoto, M Nagane, M Sone, M Takekawa, MC Hollander, N Kitagawa, Paul H Patterson, Q Zhan, Q Zhan, R Lahav, R Lahav, S He, S Jin, S Jin, S Velasco-Miguel, SP Harland, U Pagotto, V Naidoo, XW Wang, Y Berger   +42 more
core   +3 more sources

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Functional selectivity of GPCR-directed drug action through location bias. [PDF]

, 2017
G-protein-coupled receptors (GPCRs) are increasingly recognized to operate from intracellular membranes as well as the plasma membrane. The β 2 -adrenergic GPCR can activate G s -linked cyclic AMP (G s -cAMP) signaling from endosomes.
Conti, Marco, Huang, Bo, Irannejad, Roshanak, Mika, Delphine, Pessino, Veronica, von Zastrow, Mark, Wedegaertner, Philip B.   +6 more
core   +3 more sources

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Biological control potential of worrisome wheat blast disease by the seed endophytic bacilli

Frontiers in Microbiology
Crop production often faces challenges from plant diseases, and biological control emerges as an effective, environmentally friendly, cost-effective, and sustainable alternative to chemical control.
Musrat Zahan Surovy, Sudipta Dutta, Nur Uddin Mahmud, Dipali Rani Gupta, Tarin Farhana, Sanjay Kumar Paul, Joe Win, Christopher Dunlap, Ricardo Oliva, Mahfuzur Rahman, Andrew G. Sharpe, Tofazzal Islam   +11 more
doaj   +1 more source

Antagonists of Evil in the Works of J. R. R. Tolkien and Nato Davitashvili

Nalans, 2021
The article deals with the main characteristics of the antagonists in Fantasy literature. Evil characters have always existed in different literary works. However, in fantasy literature the main antagonist is definitely evil.
Tamar Katamadze
doaj  

A Novel Small-Molecule Inhibitor of Endosomal TLRs Reduces Inflammation and Alleviates Autoimmune Disease Symptoms in Murine Models

Cells, 2020
Toll-like receptors (TLRs) play a fundamental role in the inflammatory response against invading pathogens. However, the dysregulation of TLR-signaling pathways is implicated in several autoimmune/inflammatory diseases.
Mahesh Chandra Patra, Asma Achek, Gi-Young Kim, Suresh Panneerselvam, Hyeon-Jun Shin, Wook-Yong Baek, Wang Hee Lee, June Sung, Uisuk Jeong, Eun-Young Cho, Wook Kim, Eunha Kim, Chang-Hee Suh, Sangdun Choi   +13 more
doaj   +1 more source

Galanin receptor 2 modifies neuropeptide Y Y1 receptor internalization and β-Arrestin recruitment [PDF]

, 2015
We have recently described a Galanin receptor 2(GALR2) and Neuropeptide Y Y1 receptor(NPYY1R) interaction at behavioural, cellular and receptor levels through GALR2/NPYY1R heterodimers.
Borroto-Escuela, Dasiel, Díaz-Cabiale, Zaida, Flores-Burgess, Antonio, Fuxe, Kjell, Gago, Belén, Millón, Carmelo, Narváez, José Ángel, Narváez, Manuel, Santin-Nuñez, Luis Javier   +8 more
core  

Communication over the network of binary switches regulates the activation of A$_{2A}$ adenosine receptor

, 2014
Dynamics and functions of G-protein coupled receptors (GPCRs) are accurately regulated by the type of ligands that bind to the orthosteric or allosteric binding sites.
Choi, Sun, Hyeon, Changbong, Lee, Yoonji
core   +3 more sources