Results 131 to 140 of about 1,151,656 (283)

Therapeutic Prospects of Ketamine for Cataplexy in Narcolepsy Type 1: Evidence from a Human Case and a Murine Model

Annals of Neurology, EarlyView.
Narcolepsy type 1 is characterized by cataplexy, for which current treatments targeting monoaminergic, histaminergic, and GABAergic pathways may be ineffective or poorly tolerated. We report the case of a 34‐year‐old man with narcolepsy type 1, intolerant to standard therapies, who experienced marked and sustained cataplexy reduction with morning ...
Francois Ricordeau, Sebastien Arthaud, Leila Langbour, Silvia Melzi, Aurelie Richard‐Mornas, Hannah Doudoux, Benjamin Rolland, Laure Peter‐Derex, Christelle Peyron   +8 more
wiley   +1 more source

Post-mortem molecular profiling of three psychiatric disorders

Genome Medicine, 2017
Background Psychiatric disorders are multigenic diseases with complex etiology that contribute significantly to human morbidity and mortality. Although clinically distinct, several disorders share many symptoms, suggesting common underlying molecular ...
Ryne C. Ramaker, Kevin M. Bowling, Brittany N. Lasseigne, Megan H. Hagenauer, Andrew A. Hardigan, Nicholas S. Davis, Jason Gertz, Preston M. Cartagena, David M. Walsh, Marquis P. Vawter, Edward G. Jones, Alan F. Schatzberg, Jack D. Barchas, Stanley J. Watson, Blynn G. Bunney, Huda Akil, William E. Bunney, Jun Z. Li, Sara J. Cooper, Richard M. Myers   +19 more
doaj   +1 more source

SpartanAnatomy.org: Evaluating a new interactive neuroradiology tool for early medical education

Anatomical Sciences Education, EarlyView.
Abstract Teaching neuroanatomy through the lens of magnetic resonance imaging (MRI) offers medical students a strong foundation for success. However, many existing MRI learning resources lack interactivity and user‐friendliness, require payment, or include an overwhelming number of labeled structures.
Halie Kerver, Cody Lee, Danielle Keller, Ruxin Shi   +3 more
wiley   +1 more source

Neural activity dissociation between thought-based and perception-based response conflict [PDF]

, 2007
Based on the idea that intentions have different penetrability to perception and thought (Fodor, 1983), four Stroop-like tasks, AA, AW, WA, and WW are used, where the A represents an arrow and the CPPR (closest processing prior to response) is perception,
Dezhong Yao, Qiang Liu, Hong Li, Antao Chen, Qinglin Zhang, Xu Lei, Yongxiu Lai, Xiting Huang   +7 more
core  

Context, not conflict, drives cognitive control [PDF]

, 2012
Theories of cognitive control generally assume that perceived conflict acts as a signal to engage inhibitory mechanisms that suppress subsequent conflicting information.
Schlaghecken, Friederike, Martini, Paolo, Paolo Martini, Friederike Schlaghecken   +3 more
core   +1 more source

Effects of Cannabidiol‐Rich Cannabis Oil on Facial Expression Recognition and Theory of Mind in Children With Autism Spectrum Disorder: A Randomized Clinical Trial

Autism Research, EarlyView.
ABSTRACT To evaluate, in a post hoc subanalysis, the effects of cannabidiol (CBD)‐rich cannabis oil on facial expression recognition and theory of mind in children with autism spectrum disorder (ASD). This post hoc subanalysis included children from a double‐blind, randomized, placebo‐controlled trial who completed social cognition assessments at ...
Wandersonia Moreira Brito Medeiros, Estácio Amaro da Silva Junior, Katy Lísias Gondim Dias de Albuquerque, Marine Diniz da Rosa, Amanda Gleiciane de Lima Oliveira, Maycon Jônatas da Silva, João Vitor Andrade Fernandes, Emily Caroline Costa Vieira, João Paulo Mendes dos Santos, Thais Cavalcanti Borges, Ana Hermínia Andrade e Silva, Carlos Espínola Neto Segundo, Nelson Torro‐Alves   +12 more
wiley   +1 more source

Illusory Obesity Triggers Body Dissatisfaction Responses in the Insula and Anterior Cingulate Cortex

Cerebral Cortex, 2016
In today's Western society, concerns regarding body size and negative feelings toward one's body are all too common. However, little is known about the neural mechanisms underlying negative feelings toward the body and how they relate to body perception ...
C. Preston, H. H. Ehrsson
semanticscholar   +1 more source

Anterior insular cortex is necessary for empathetic pain perception

, 2012
Empathy refers to the ability to perceive and share another person's affective state. Much neuroimaging evidence suggests that observing others' suffering and pain elicits activations of the anterior insular and the anterior cingulate cortices associated
Fan, J (reprint author), CUNY Queens Coll, Dept Psychol, 65-30 Kissena Blvd, Flushing, NY 11367 USA., Wang, Xingchao, Gao, Zhixian, Gu, Xiaosi, Fan, Jin, Hof, Patrick R., Liu, Xun, Knight, Robert T.   +7 more
core   +1 more source

Animal empathy reconsidered: a multidimensional profile account

Biological Reviews, EarlyView.
ABSTRACT Empathy is the glue that holds societies together and yet several fundamental questions about empathy persist. What is empathy (the definitional question)? Is it uniquely human and, if not, which nonhuman animals possess empathy (the distribution question)? Which type or quality of empathy is realized in different species (the quality question)
Albert Newen, Maja Griem, Ludwig Huber, Thomas Bugnyar, Aaron Blaisdell, Simone Pika   +5 more
wiley   +1 more source

Observational learning computations in neurons of the human anterior cingulate cortex

Nature Communications, 2016
When learning from direct experience, neurons in the primate brain have been shown to encode a teaching signal used by algorithms in artificial intelligence: the reward prediction error (PE)—the difference between how rewarding an event is, and how ...
Michael R. H. Hill, E. Boorman, I. Fried
semanticscholar   +1 more source