Results 111 to 120 of about 172,666 (300)

Optimal decision making and the anterior cingulate cortex

Nature Neuroscience, 2006
Learning the value of options in an uncertain environment is central to optimal decision making. The anterior cingulate cortex (ACC) has been implicated in using reinforcement information to control behavior. Here we demonstrate that the ACC's critical role in reinforcement-guided behavior is neither in detecting nor in correcting errors, but in ...
Kennerley, S, Walton, M, Behrens, T, Buckley, M, Rushworth, M   +4 more
openaire   +2 more sources

Foreign Language Learning in Older Adults Modifies Resting‐State Functional Connectivity Between the Subcortical Structures and the Cortex

AGING MEDICINE, EarlyView.
Foreign language learning in older adults reorganizes thalamic and caudate connectivity, in a process topographically overlapping with the expression of receptors and genes related to neuroplasticity. ABSTRACT Objectives Neuroimaging studies suggest that Foreign Language Learning (FLL) influences resting‐state functional connectivity (rs‐FC) within the
Giovanna Bubbico, Federica Tomaiuolo, Carlo Sestieri, Golnoush Akhlaghipour, Alberto Granzotto, Antonio Ferretti, Mauro Gianni Perrucci, Stefano L. Sensi, Stefano Delli Pizzi   +8 more
wiley   +1 more source

Reduced CB1 Cannabinoid Receptor Expression in Alzheimer's Disease and Transgenic Mouse Models

AGING MEDICINE, EarlyView.
CB1 receptor (CB1R) expression was significantly reduced in the hippocampus, medial frontal gyrus, and superior temporal gyrus of Alzheimer's patients. CB1R levels negatively correlated with amyloid‐β and tau pathology. In addition, CB1R expression was also reduced in the cortex of 5xFAD mice and in the hippocampus of Tg4‐42 mice.
Nike von Borcke, Amrei Vivian Purwien, Annik Steiert, Henrike Hasecke, Yvonne Bouter   +4 more
wiley   +1 more source

Neural correlates of processing valence and arousal in affective words [PDF]

, 2007
Psychological frameworks conceptualize emotion along 2 dimensions, "valence" and "arousal." Arousal invokes a single axis of intensity increasing from neutral to maximally arousing.
Critchley, H.D., Dolan, R.J., Lewis, P.A., Rotshtein, P.   +3 more
core  

Where does brain neural activation in aesthetic responses to visual art occur? Meta-analytic evidence from neuroimaging studies [PDF]

, 2016
Here we aimed at finding the neural correlates of the general aspect of visual aesthetic experience (VAE) and those more strictly correlated with the content of the artworks. We applied a general activation likelihood estimation (ALE) meta-analysis to 47
Barbetti, S., Boccia, Maddalena, Ferlazzo, Fabio, Giannini, Anna Maria, Guariglia, Cecilia, Piccardi, Laura, Zaidel, D. W.   +6 more
core   +1 more source

Cytosolic Phosphoenoylpyruvate Carboxykinase Deficiency: Clinical, Biochemical, and Genetic Features of Five Non‐Finnish Patients

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Cytosolic phosphoenoylpyruvate carboxykinase (PEPCK‐C) is an essential, rate‐limiting enzyme in the gluconeogenesis pathway. PEPCK‐C deficiency presents with hypoglycaemia, hyperlactataemia and hepatopathy, and was first reported in association with bi‐allelic PCK1 variants in 2014.
Isaac Bernhardt, Polona Le Quesne Stabej, Claire Hart, Mark De Hora, Sarah Hulley, Mark Anderson, Harry G. Leitch, Hugh Lemonde, Bryony Ryder, James Davison   +9 more
wiley   +1 more source

Resting-state coupling between core regions within the central-executive and salience networks contributes to working memory performance

Frontiers in Behavioral Neuroscience, 2016
Previous studies investigated the distinct roles played by different cognitive regions and suggested that the patterns of connectivity of these regions are associated with working memory.
Xiaojing eFang, Yuanchao eZhang, Yuan eZhou, Luqi eCheng, Jin eLi, Yulin eWang, Karl eFriston, Tianzi eJiang, Tianzi eJiang, Tianzi eJiang, Tianzi eJiang, Tianzi eJiang   +11 more
doaj   +1 more source

Implementation of error-processing in the human anterior cingulate cortex : a source analysis of the magnetic equivalent of the error-related negativity

, 2003
A
Coles, Michael G.H., Holroyd, Clay, Lemke, Ulrike, Miltner, Wolfgang H.R., Scheffers, Marten K., Weiss, Thomas   +5 more
core   +2 more sources

State-dependent changes of connectivity patterns and functional brain network topology in Autism Spectrum Disorder [PDF]

, 2012
Anatomical and functional brain studies have converged to the hypothesis that Autism Spectrum Disorders (ASD) are associated with atypical connectivity.
Barttfeld, Pablo, Cukier, Sebastián, Leiguarda, Ramón, Lew, Sergio, Navarta, Silvana, Sigman, Mariano, Wicker, Bruno   +6 more
core   +2 more sources

Auditory Hyperresponsivity in Chronic Back Pain: A Randomized Controlled Trial of Pain Reprocessing Therapy

Annals of Neurology, EarlyView.
Objective Heightened sensitivity to noxious stimulation is a hallmark of chronic pain. Emerging evidence suggests heightened unpleasantness to non‐noxious (eg, auditory) aversive stimulation also characterizes chronic pain, but its magnitude, neural mechanisms, and treatment modifiability remain unknown.
Alina E. C. Panzel, Christian Büchel, Andrew Leroux, Tor D. Wager, Yoni K. Ashar   +4 more
wiley   +1 more source