Results 141 to 150 of about 2,661,021 (354)

Dynamic imaging of accommodation by swept-source anterior-segment optical coherence tomography

Journal of cataract and refractive surgery, 2015
Purpose To study the accommodation process in normal eyes using a commercially available clinical system based on swept‐source anterior segment optical coherence tomography (AS‐OCT). Setting Ophthalmology Department, University of Parma, Italy.
A. Neri, M. Ruggeri, A. Protti, R. Leaci, S. Gandolfi, C. Macaluso   +5 more
semanticscholar   +1 more source

The Involutional Change of the Anterior Segment Morphology, Intraocular Pressure and Ocular Pulse Amplitude and the Effect of Glaucoma on this Change [PDF]

, 2013
Pur po se: To assess the involutional change of the anterior segment morphology, intraocular pressure, ocular pulse amplitude and the effect of glaucoma on these parameters.
Ebru Cömert, Barış Sönmez, Volkan Yeter, İhsan Öge, Ümit Beden, Seda Kuruoğlu,, Mehtap Özarslan   +6 more
core   +1 more source

Immediate Versus Delayed Sequential Bilateral Cataract Surgery: A Systematic Review

Clinical Ophthalmology
Samar Al-Swailem,1 Khabir Ahmad,2 Abdulaziz Jabr AlJbreen,3 Sara AlHilali1 1Anterior Segment Division, King Khaled Eye Specialist Hospital and Research Center, Riyadh, Saudi Arabia; 2Research Department, King Khaled Eye Specialist Hospital and Research ...
Al-Swailem S, Ahmad K, AlJbreen AJ, AlHilali S   +3 more
doaj  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Surgical management of chronic Stevens-Johnson syndrome

Frontiers in Medicine
Stevens-Johnson Syndrome (SJS) is a rare but severe mucocutaneous disorder that often leads to chronic ocular complications, requiring a comprehensive and multidisciplinary approach to management.
Aastha Garg, Abha Gour, Nidhi Chauhan, Mehak Sapra, Virender Singh Sangwan   +4 more
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Anterior Segment Vessels Filter [PDF]

<p>Anterior Segment Vessels Filter: This is a filter to enhance the binary visibility and measurability of the conjunctival and scleral vessels in images taken with an anterior segment camera, fixing the thickness and sharpness of branching ...
Arath A., Alejandro-Rodríguez
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

A case of optic-nerve hypoplasia and anterior segment abnormality associated with facial cleft [PDF]

, 2016
Tomoko Miyake,1 Shota Kojima,1 Tetsuya Sugiyama,2 Mari Ueki,1 Jun Sugasawa,1 Hidehiro Oku,1 Kensuke Tajiri,1 Yuka Shigemura,3 Koichi Ueda,3 Atsuko Harada,4 Mami Yamasaki,4 Takumi Yamanaka,4 Hidetsuna Utsunomiya,5 Tsunehiko Ikeda1 1Department of ...
Shigemura Y, Kojima S, Yamanaka T, Sugasawa J, Oku H, Yamasaki M, Ikeda T, Ueda K, Tajiri K, Sugiyama T, Ueki M, Utsunomiya H, Harada A, Miyake T   +13 more
core