Results 121 to 130 of about 247,139 (266)

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Anterior Segment Eye Diseases and Quality of Life: An Updated Comprehensive Narrative Review. [PDF]

J Ophthalmic Vis Res
Khorrami-Nejad M, Narooie-Noori F, Al-Khafaji Q, Hashemian H, Dhubhghaill SN, Daya S.   +5 more
europepmc   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Comparison of anterior segment parameter measurements between Sirius Plus and Pentacam AXL. [PDF]

Front Med (Lausanne)
Ning J, Zhang L.
europepmc   +1 more source

Evaluation of a New Algorithm-Based Approach in Subjective Refraction

Journal of Ophthalmology
Imene Salah-Mabed, Vincent Péan, Damien Gatinel   +2 more
doaj   +1 more source

Surgical Outcomes of Lens Removal with or Without Intraocular Lens Implantation in Marfan Syndrome: A Retrospective Cohort Study

Clinical Ophthalmology
Halah Bin Helayel,1 Moustafa S Magliyah,2 Raed Alnutaifi,3 Abdulrahman H Badawi2 1Anterior Segment Division, King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia; 2Vitreoretinal Division, King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia ...
Bin Helayel H, Magliyah MS, Alnutaifi R, Badawi AH   +3 more
doaj  

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

High-Resolution Anterior Segment Optical Coherence Tomography Characteristics of Conjunctival Tumors. [PDF]

J Clin Pract Res
Ocaktan O, Horozoglu F, Sener H, Özer F.   +3 more
europepmc   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Recent Achievements and Perspectives in Nebulization Devices for Anterior Segment Disease Treatment. [PDF]

Pharmaceutics
Liu H, Deng Q, Cao J, Wang T, Chen J, Xiong K.   +5 more
europepmc   +1 more source