Results 111 to 120 of about 247,139 (266)

THE SIGNIFICANCE OF THE ANTERIOR SEGMENT IN BRONCHIECTASIS

Journal of Thoracic Surgery, 1955
R H, OVERHOLT, W B, NEPTUNE
openaire   +2 more sources

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

A Datasheet for the INSIGHT Moorfields Cornea Anterior Segment Dataset (CADMUS). [PDF]

Ophthalmol Sci
Balal S, Alsafi Z, Leucci M, Keane PA, Gore D, Pontikos N, Allan BD.   +6 more
europepmc   +1 more source

Occupationally Acquired Polymicrobial Keratitis Caused by Acanthamoeba and Rare Enteric Bacteria Following Gastrointestinal Splash Exposure: A Case Report

Case Reports in Infectious Diseases
Fatma Elnaggar, Heba AlSharif, Muhammad Haris Mazhar, Danya Aldahan, Halah Bin Helayel   +4 more
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Normative Values for Anterior Segment Parameters Associated with Glaucoma in "At-Risk" Ghanaian Clinical Population. [PDF]

Clin Ophthalmol
Nelson-Ayifah D, Munsamy AJ, Mashige KP.
europepmc   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Cytomegalovirus Infection of the Anterior Segment: Corneal Endotheliitis and Secondary Glaucoma. [PDF]

Pathogens
Liu F, Zou Y, Yang M, Zhang J, Ohno-Matsui K, Kamoi K.   +5 more
europepmc   +1 more source

Fungal Keratitis Following Application of Dehydrated Amniotic Membrane (Omnigen) With (OmniLenz) Bandage Contact Lens

Case Reports in Ophthalmological Medicine
Bayan Ali Alsaif, Albaraa T. Alfaraidi, Rawan Alshabeeb   +2 more
doaj   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source