Results 101 to 110 of about 2,661,021 (354)

Secretory Leukoprotease Inhibitor: A Native Antimicrobial Protein in the Innate Immune Response in a Rat Model of S. aureus Keratitis

Journal of Ophthalmology, 2009
Purpose. To describe the presence of secretory leukocyte protease inhibitor (SLPI), a cationic peptide with antimicrobial and antiprotease activity in the innate immune reaction in a rat model of Staphylococcus aureus keratitis. Methods.
Victor E. Reviglio, Andres Grenat, Federico Pegoraro, Ruben H. Sambuelli, Tayyib Rana, Irene C. Kuo   +5 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Performance and Safety of a Sodium Hyaluronate, Xanthan Gum, and Osmoprotectants Ophthalmic Solution in the Treatment of Dry Eye Disease: An Observational Clinical Investigation

Ophthalmology and Therapy
Introduction Dry eye disease (DED) is characterized by an imbalance in the tear film, resulting in symptoms such as dryness, redness, and discomfort. The management of DED involves tear supplements, medications, or surgery in severe cases.
Mercedes Molero Senosiaín, Barbara Burgos-Blasco, Pilar Perez-García, Álvaro Sánchez-Ventosa, Marta Villalba-González, María Dolores López Pérez, José Carlos Díaz, Vanesa Díaz-Mesa, Alberto Villarrubia Cuadrado, Enrique Artiaga Elordi, Jose Manuel Larrosa Poves, Alejandro Blasco, Antonio Mateo, Claudine Civiale, Laura Bonino, Antonio Cano-Ortiz   +15 more
doaj   +1 more source

Self-inflicted eye injury

Annals of Saudi Medicine, 2017
Individuals with a factitious ocular disorder feign or exaggerate having an eye injury or intentionally produce an eye injury so as to assume the role of a sick person.
Mohammed A. Gogandy, Abdulqader Aljarad, Sabah S. Jastaneiah, Abdullah M. Alfawaz   +3 more
doaj   +1 more source

Mutations in CPAMD8 Cause a Unique Form of Autosomal-Recessive Anterior Segment Dysgenesis

American Journal of Human Genetics, 2016
Anterior segment dysgeneses (ASDs) comprise a spectrum of developmental disorders affecting the anterior segment of the eye. Here, we describe three unrelated families affected by a previously unclassified form of ASD.
Sek-Shir Cheong, Lisa-Henrike Hentschel, A. Davidson, D. Gerrelli, Rebecca Davie, Roberta Rizzo, Nikolas Pontikos, V. Plagnol, A. Moore, J. Sowden, M. Michaelides, M. Snead, S. Tuft, A. Hardcastle   +13 more
semanticscholar   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

Anterior segment findings. [PDF]

, 2019
Anterior segment findings.
Langis Michaud (6889433)
core   +1 more source

α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates

FEBS Letters, EarlyView.
Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino, Giuliana Fusco, Alfonso De Simone   +2 more
wiley   +1 more source

Mild toxic anterior segment syndrome mimicking delayed onset toxic anterior segment syndrome after cataract surgery [PDF]

, 2014
Toxic anterior segment syndrome (TASS) is an acute sterile postoperative anterior segment inflammation that may occur after anterior segment surgery. I report herein a case that developed mild TASS in one eye after bilateral uneventful cataract surgery ...
Su-Na Lee
core   +1 more source

Changing Strategies in Keratoplasty After Corneal Hydrops: From Penetrating to Lamellar Approaches – A Narrative Review

Clinical Ophthalmology
Rafah Fairaq,1 Omar Kirat,1 Mohammed AlMutlak,1 Muhammad A Ahad,1 Omar Khan,1,2 Ahmed AlDayel,1 Saud Abdulbadie Khan,2 Mozon Alshareef,3 Wejdan Saeed Alghamdi,1 Halah Bin Helayel1 1Anterior Segment Division, King Khalid Eye Specialist Hospital, Riyadh ...
Fairaq R, Kirat O, AlMutlak M, Ahad MA, Khan O, AlDayel A, Khan SA, Alshareef M, Alghamdi WS, Bin Helayel H   +9 more
doaj