Results 51 to 60 of about 2,733,104 (305)

Anterior Segment OCT: High-Resolution Tomography of Corneal and Conjunctival Lesions

, 2020
Anterior segment high-resolution optical coherence tomography (HR-OCT) plays a pivotal role in the diagnosis of corneal and conjunctival lesions. Ocular surface squamous neoplasia (OSSN), the most common non-pigmented neoplasia of squamous cell origin ...
Asaf Friehmann, Theotoka, Despoina, Karp, Carol L., Despoina Theotoka, Sarah Wall, Friehmann, Asaf, Carol L. Karp, Wall, Sarah   +7 more
core   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Primary congenital glaucoma: An iridotrabeculodysgenesis?

Indian Journal of Ophthalmology
Purpose: To analyze primary congenital glaucoma (PCG) anterior chamber and angle anomalies over 360° as possible biomarkers of severity and prognosis. Methods: A cross-sectional observational study was conducted analyzing anterior segment anomalies of ...
Ramanjit Sihota, Karthikeyan Mahalingam, Ashok Kumar Maurya, Ajay Sharma, Anand Naik Bukke, Tanuj Dada   +5 more
doaj   +1 more source

Evaluation of Epithelial Downgrowth Using Anterior Segment Optical Coherence Tomography: A Case Report

, 2013
Epithelial downgrowth is a rare, sight-threatening complication which can develop following anterior segment surgeries with corneal incisions. However, due to translucent nature of epithelial membrane and diversity of clinical signs, epithelial ...
Alime Güneş, Tahir Kansu Bozkurt, Banu Torun Acar, Hüseyin Bayramlar, Alev Kahya Kochkarov, Ayşe Ebru Bahadır   +5 more
core   +1 more source

Repeatability of Orbscan III for anterior segment parameters in normal eyes

Indian Journal of Ophthalmology, 2020
Assessment of repeatability of Orbscan III in measuring steep keratometry (sKm), flat keratometry (fKm), thinnest corneal thickness (TCT), anterior chamber depth (ACD), white-to-white diameter (WTW) and 3 mm and 5 mm zonal irregularity in healthy eyes.In this prospective observatioanl study 100 eyes of 50 participants underwent three consecutive scans ...
Sharma, Mohita, Jain, Neha, Koshy, Ann S, Arora, Vishal, Lalgudi, Vaitheeswaran G   +4 more
openaire   +2 more sources

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Association between blink-related anterior segment dynamics and intraocular pressure

Scientific Reports
Intraocular pressure (IOP) is a key parameter for diagnosing and managing glaucoma. This study introduces a novel, non-contact method for evaluating blink-induced anterior segment dynamics, as observed through corneal profile motion during natural ...
Vito Ivano D’Alessandro, Filippo Attivissimo, Attilio Di Nisio, Anna Lanzolla, Amal Isaiah, Giuliano Scarcelli   +5 more
doaj   +1 more source

Visualization of hyaluronic acid in the anterior segment of rabbit and monkey eyes [PDF]

, 1990
Hyaluronic acid was visualized using a new histochemical technique: the hyaluronic acid-binding region of the cartilage proteoglycan was isolated, linked with biotin and used in histological sections as a ligand for hyaluronic acid.
Tengblad, A., Tamm, Ernst R., Schenholm, M., Lütjen-Drecoll, E.   +3 more
core   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Bimanual anterior segment revision surgery for anterior capsule contraction syndrome associated with anterior flexion of intraocular lens haptics

, 2013
PURPOSE To report the incidence of anterior capsule contraction syndrome (ACCS) and to present a novel minimally invasive bimanual technique for anterior segment revision surgery associated with ACCS with anterior flexion of the intraocular lens ...
Zinkernagel, Martin, Papazoglou, A., C K Patel, M Zinkernagel, Patel, C. K., A Papazoglou   +5 more
core   +1 more source