Results 41 to 50 of about 41,351 (280)

ANTHELMINTIC DRUGS EFFICACY AGAINST BOVINE FASCIOLIASIS

Ветеринарная патология, 2022
Parasitic diseases in cattle are widespread in the territory of the Russian Federation. At the farms of Udmurtia various kinds of ruminants parasitic fauna are represented and therefore the vast use of antiparasitic drugs entails a range of problems ...
E. S. Klimova
doaj   +1 more source

Identification of small molecule enzyme inhibitors as broad-spectrum anthelmintics

Scientific Reports, 2019
Targeting chokepoint enzymes in metabolic pathways has led to new drugs for cancers, autoimmune disorders and infectious diseases. This is also a cornerstone approach for discovery and development of anthelmintics against nematode and flatworm parasites.
R. Tyagi, M. Elfawal, S. Wildman, Jonathan D. M. Helander, Christina A. Bulman, J. Sakanari, B. Rosa, P. Brindley, J. Janetka, R. Aroian, M. Mitreva   +10 more
semanticscholar   +1 more source

Small Molecule Inhibitors of Metabolic Enzymes Repurposed as a New Class of Anthelmintics.

ACS Infectious Diseases, 2018
The enormous prevalence of infections caused by parasitic nematodes worldwide, coupled to the rapid emergence of their resistance to commonly used anthelmintic drugs, presents an urgent need for the discovery of new drugs.
R. Tyagi, A. R. Maddirala, M. Elfawal, Chelsea Fischer, Christina A. Bulman, B. Rosa, Xin Gao, Ryan Chugani, Mingzhou Zhou, Jonathan D. M. Helander, P. Brindley, C. Tseng, I. Greig, J. Sakanari, S. Wildman, R. Aroian, J. Janetka, M. Mitreva   +17 more
semanticscholar   +1 more source

Optimal schemes for the use of anthelmintics at gastrointestinal strongylatosis of young cattle

Российский паразитологический журнал, 2023
The purpose of the research is to study the rational terms for the use of anthelmintics in case of gastrointestinal strongylatoses of young cattle in Nonchernozem zone of the Russian Federation.Materials and methods.
I. A. Arkhipov, A. I. Varlamova, E. O. Kachanova   +2 more
doaj   +1 more source

ChemInform Abstract: Piperazinoarylthiocarbamides and Anthelmintics.

Chemischer Informationsdienst, 1986
AbstractDie auf dem angegebenen Weg hergestellten Thiocarbamate (IV) zeigen Wirkung als Anthelmintica.
Karuna Shanker, Anil K. Saxena, R. Yasmeen, S. Ahmad, K. P. Bhargava   +4 more
openaire   +2 more sources

Field evaluation of the efficacy of common anthelmintics used in the control of gastrointestinal nematodes of sheep in Dabat district, Northwest Ethiopia

Irish Veterinary Journal, 2017
BackgroundGastrointestinal nematode (GIN) infections are the main impediments that restrict the welfare and productivity of small ruminant in the world.
Z. Seyoum, Yitayew Demessie, Basazinew Bogale, A. Melaku   +3 more
semanticscholar   +1 more source

Reprofiled anthelmintics abate hypervirulent stationary-phase Clostridium difficile

Scientific Reports, 2016
Prolonged use of broad-spectrum antibiotics disrupts the indigenous gut microbiota, which consequently enables toxigenic Clostridium difficile species to proliferate and cause infection. The burden of C.
Major Gooyit, K. Janda
semanticscholar   +1 more source

Green Synthesis of Silver Nanoparticles: A Review of Polymer and Antimicrobial Drug Combinations for Enhanced Antimicrobial Applications

Advanced NanoBiomed Research, EarlyView.
Silver nanoparticles (AgNPs) synthesized using eco‐friendly green synthesis approaches exhibit remarkable antimicrobial activity and enhanced drug delivery potential. Polymer‐AgNPs conjugates further improve drug stability and targeted delivery, offering a multifunctional platform for biomedical applications.
Mukil Madhusudanan, Jian Zhang, Santosh Pandit, Priyanka Singh, Geum‐Jae Jeong, Fazlurrahman Khan, Ivan Mijakovic   +6 more
wiley   +1 more source

Host pharmacokinetics and drug accumulation of anthelmintics within target helminth parasites of ruminants

New Zealand Veterinary Journal, 2017
Anthelmintic drugs require effective concentrations to be attained at the site of parasite location for a certain period to assure their efficacy. The processes of absorption, distribution, metabolism and excretion (pharmacokinetic phase) directly ...
A. Lifschitz, C. Lanusse, L. Alvarez
semanticscholar   +1 more source

First Report on some N2O2‐Donor Sets Tetradentate Schiff Base and Its Metal Complexes: Characterization and Antimicrobial Investigation

Chemistry &Biodiversity, EarlyView.
Mass spectrometry, UV‐Vis. spectra, thermal analysis and antimicrobial evaluation were done for a novel tetradentate Schiff base ligand (H2L) and its metal complexes. ABSTRACT The new Schiff base ligand N,N′‐thiophene‐(bis‐1‐ethyl‐6,8‐difluoro‐7‐(3‐methylpiperazin‐1‐yl)‐4‐oxo‐1,4‐dihydroquinoline‐3‐carboxylic acid) (H2L) was synthesized via ...
Amira A. Mohamed, Mohammed S. El‐Gedamy, Sadeek A. Sadeek, Hazem S. Elshafie   +3 more
wiley   +1 more source