Non-Natural Linker Configuration in 2,6-Dipeptidyl-Anthraquinones Enhances the Inhibition of TAR RNA Binding/Annealing Activities by HIV-1 NC and Tat Proteins [PDF]
, 2018 The HIV-1 nucleocapsid (NC) protein represents an excellent molecular target for the development of antiretrovirals by virtue of its well-characterized chaperone activities, which play pivotal roles in essential steps of the viral life cycle. Our ongoing
Caliendo, Giuseppe +16 more
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Natural Products and Their Derivatives against Human Herpesvirus Infection
Molecules, 2021 Herpesviruses establish long-term latent infection for the life of the host and are known to cause numerous diseases. The prevalence of viral infection is significantly increased and causes a worldwide challenge in terms of health issues due to drug ...
Chattarin Ruchawapol +4 more
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Anthraquinones tautomerism: VII. Hydroxy-substituted anthraquinones
Russian Journal of Organic Chemistry, 2007 Tautomerism of β-mono-, β,β'-dihydroxyanthraquinones, and their anions was studied for the first time by quantum-chemical and correlation methods. 2-Hydroxyanthraquinone exists exclusively in 9,10-quinoid form, and its ionization involves a tautomeric transformation into 10-oxido-2,9- anthraquinone.
Fain V.Ya., Zaitsev B.E., Ryabov M.A.
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Comparative density functional theory study on the relative gas phase enthalpies and free energies of formation for the mono- through hepta-halogenated (X=F, Cl, Br) anthraquinones [PDF]
, 2010 Gas phase standard state (298.15 K, 1 atmosphere) relative enthalpies and free energies of formation were calculated for all mono- through hepta-halogenated (X=F, Cl, Br) anthraquinone congeners using the B3LYP, BHandHLYP, M062X, PBE0, and B97D density ...
Kaya Forest, Sierra Rayne
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Saudi Pharmaceutical Journal, 2019 Rhei rhizome (Rheum officinale Baill.) (RR) contains a large number of anthraquinone bioactive, yet little is known of the combined effect of these anthraquinones in a mixture.
Zeyad Alehaideb +3 more
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Antiglycation activity and HT-29 cellular uptake of aloe-emodin, aloin, and aloe arborescens leaf extracts [PDF]
, 2019 Aloe arborescens is a relevant species largely used in traditional medicine of several countries. In particular, the decoction of leaves is prepared for various medicinal purposes including antidiabetic care. The aim of this research was the study of the
Baronchelli, F. +3 more
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Molecules, 2023 Emodin-8-O-glucoside (E-8-O-G) is a glycosylated derivative of emodin that exhibits numerous biological activities, including immunomodulatory, anti-inflammatory, antioxidant, hepatoprotective, or anticancer activities.
Estera Okon +7 more
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Anthraquinones as Inhibitors of SOS RAS-GEF Activity
Biomolecules, 2021 Recent breakthroughs have reignited interest in RAS GEFs as direct therapeutic targets. To search for new inhibitors of SOS GEF activity, a repository of known/approved compounds (NIH-NACTS) and a library of new marine compounds (Biomar Microbial ...
Alberto Fernández-Medarde +6 more
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Preparative isolation of anthraquinones from the fungus Dermocybe sanguinea using enzymatic hydrolysis by the endogenous beta-glucosidase [PDF]
, 2000 Peer ...
Elovaara, Pia +3 more
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Anthracene and Anthraquinone [PDF]
Nature, 1921 THE history of anthracene is long and vivid. Discovered amongst the products of coal-tar distillation in 1832, the hydrocarbon played a modest and somewhat commonplace part in the development of structural theory, suddenly blossoming into prominence in 1868, when it was found that alizarin, the twin monarch with indigo of natural colouring matters, is ...
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